Zobrazeno 1 - 10
of 202
pro vyhledávání: '"chromosome missegregation"'
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
For over 100-years, genomic instability has been investigated as a central player in the pathogenesis of human cancer. Conceptually, genomic instability includes an array of alterations from small deletions/insertions to whole chromosome alterations,
Externí odkaz:
https://doaj.org/article/262af412051243bfb30305460957821a
Autor:
Eva R. Shteinman, James S. Wilmott, Ines Pires da Silva, Georgina V. Long, Richard A. Scolyer, Ismael A. Vergara
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Aneuploidy, the state of the cell in which the number of whole chromosomes or chromosome arms becomes imbalanced, has been recognized as playing a pivotal role in tumor evolution for over 100 years. In melanoma, the extent of aneuploidy, as well as t
Externí odkaz:
https://doaj.org/article/402df30310de447fa50da6bee3d68f22
Akademický článek
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Autor:
Bjerregaard, Victoria A., Garribba, Lorenza, McMurray, Cynthia T., Hickson, Ian D., Liu, Ying
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2018 Dec . 115(51), 13003-13008.
Externí odkaz:
https://www.jstor.org/stable/26574211
Autor:
Arthur R. Gorter de Vries, Ewout Knibbe, Roderick van Roosmalen, Marcel van den Broek, Pilar de la Torre Cortés, Stephanie F. O’Herne, Pascal A. Vijverberg, Anissa el Masoudi, Nick Brouwers, Jack T. Pronk, Jean-Marc G. Daran
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
The lager-brewing yeast Saccharomyces pastorianus is a hybrid between S. cerevisiae and S. eubayanus with an exceptional degree of aneuploidy. While chromosome copy number variation (CCNV) is present in many industrial Saccharomyces strains and has b
Externí odkaz:
https://doaj.org/article/a3fef882dcec4b2f865a9fdd2fe94863
Autor:
Basu, Joydeep, Bousbaa, Hassan, Logarinho, Elsa, Li, ZeXiao, Williams, Byron C., Lopes, Carla, Sunkel, Claudio E., Goldberg, Michael L.
Publikováno v:
The Journal of Cell Biology, 1999 Jul 01. 146(1), 13-28.
Externí odkaz:
https://www.jstor.org/stable/1619415
Autor:
Marco R. Cosenza, Anna Cazzola, Annik Rossberg, Nicole L. Schieber, Gleb Konotop, Elena Bausch, Alla Slynko, Tim Holland-Letz, Marc S. Raab, Taronish Dubash, Hanno Glimm, Sven Poppelreuther, Christel Herold-Mende, Yannick Schwab, Alwin Krämer
Publikováno v:
Cell Reports, Vol 20, Iss 8, Pp 1906-1920 (2017)
Chromosomal instability is a hallmark of cancer and correlates with the presence of extra centrosomes, which originate from centriole overduplication. Overduplicated centrioles lead to the formation of centriole rosettes, which mature into supernumer
Externí odkaz:
https://doaj.org/article/193775385eee40bca446c8e132ca6f3b
Autor:
Ban, Ivana
Dioba stanica složen je proces koji počinje formiranjem diobenog vretena koje razdvaja kromosome u dvije stanice kćeri na kraju mitoze. Diobeno vreteno je mikrostroj, sazdan od mikrotubula, koji pažljivo organizira sile koje generiraju motorni pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3908::075065089f9a22407fc8a30c033cc057
https://repozitorij.pmf.unizg.hr/islandora/object/pmf:11772
https://repozitorij.pmf.unizg.hr/islandora/object/pmf:11772
Publikováno v:
Cell Reports, Vol 17, Iss 6, Pp 1632-1645 (2016)
Pairing of homologous chromosomes is a crucial step in meiosis, which in fission yeast depends on nuclear oscillations. However, how nuclear oscillations help pairing is unknown. Here, we show that homologous loci typically pair when the spindle pole
Externí odkaz:
https://doaj.org/article/630c69d1d2864caa88b643bc7818c0f7
Autor:
Maha Said, Viviana Barra, Elisa Balzano, Ibtissam Talhaoui, Franca Pelliccia, Simona Giunta, Valeria Naim
Replication stress (RS) is a leading cause of genome instability and cancer development. A substantial source of endogenous RS originates from the encounter between the transcription and replication machineries operating on the same DNA template. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94d40fb66deba5f85602f90bb59c35f4
https://hdl.handle.net/10447/592378
https://hdl.handle.net/10447/592378