Zobrazeno 1 - 10
of 837
pro vyhledávání: '"chromatin interactions"'
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
MotivationThe interaction between DNA motifs (DNA motif pairs) influences gene expression through partnership or competition in the process of gene regulation. Potential chromatin interactions between different DNA motifs have been implicated in vari
Externí odkaz:
https://doaj.org/article/6c36542491944406a0fed1ab92338ace
Publikováno v:
MedComm – Oncology, Vol 2, Iss 3, Pp n/a-n/a (2023)
Abstract Lung cancer is the leading cause of cancer‐related deaths worldwide. DNA methylation has been recognized as a potential biomarker for lung cancer diagnosis. Most reported DNA methylation biomarkers focus on promoter regions, leaving enhanc
Externí odkaz:
https://doaj.org/article/690f4a9867db4b5d8ef80f0477dda7b2
Autor:
Jason M. Torres, Vibe Nylander, Han Sun, Martijn van de Bunt, Damien J. Downes, Mark I. McCarthy, Jim R. Hughes, Anna L. Gloyn
Publikováno v:
Wellcome Open Research, Vol 8 (2023)
Background: Resolving causal genes for type 2 diabetes at loci implicated by genome-wide association studies (GWAS) requires integrating functional genomic data from relevant cell types. Chromatin features in endocrine cells of the pancreatic islet a
Externí odkaz:
https://doaj.org/article/887578fcac7042d7bd19c922142bef24
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
High-throughput chromosome conformation capture (Hi-C) technology has been applied to explore the chromatin interactions and shed light on the biological functions of three-dimensional genomic features. However, it remains challenging to guarantee th
Externí odkaz:
https://doaj.org/article/26c65d45f2e44337a05fc5ed8f27c57f
Autor:
Li Deng, Baibai Gao, Lun Zhao, Ying Zhang, Qing Zhang, Minrong Guo, Yongqing Yang, Shuangqi Wang, Liang Xie, Hao Lou, Meng Ma, Wei Zhang, Zhilin Cao, Qinghua Zhang, C. Robertson McClung, Guoliang Li, Xingwang Li
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-22 (2022)
Abstract Background The daily cycling of plant physiological processes is speculated to arise from the coordinated rhythms of gene expression. However, the dynamics of diurnal 3D genome architecture and their potential functions underlying the rhythm
Externí odkaz:
https://doaj.org/article/30006cc2886d4cddbd3ba01381b5f283
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Fan Cao, Yu Zhang, Yichao Cai, Sambhavi Animesh, Ying Zhang, Semih Can Akincilar, Yan Ping Loh, Xinya Li, Wee Joo Chng, Vinay Tergaonkar, Chee Keong Kwoh, Melissa J. Fullwood
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-25 (2021)
Abstract Chromatin interactions play important roles in regulating gene expression. However, the availability of genome-wide chromatin interaction data is limited. We develop a computational method, chromatin interaction neural network (ChINN), to pr
Externí odkaz:
https://doaj.org/article/aeb54e97cef44add957ca873496cbdf8
Autor:
Huifen Cao, Dongyang Xu, Ye Cai, Xueer Han, Lu Tang, Fan Gao, Yao Qi, DingDing Cai, Huifang Wang, Maxim Ri, Denis Antonets, Yuri Vyatkin, Yue Chen, Xiang You, Fang Wang, Estelle Nicolas, Philipp Kapranov
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-24 (2021)
Abstract Background The majority of the human genome is transcribed in the form of long non-coding (lnc) RNAs. While these transcripts have attracted considerable interest, their molecular mechanisms of function and biological significance remain con
Externí odkaz:
https://doaj.org/article/f8c11f8e08bb498fa81fb30c0f58843e
Autor:
Celina São José, Carla Pereira, Marta Ferreira, Ana André, Hugo Osório, Irene Gullo, Fátima Carneiro, Carla Oliveira
Publikováno v:
Biology, Vol 12, Iss 6, p 803 (2023)
Cadherins are cell–cell adhesion molecules, fundamental for cell architecture and polarity. E-cadherin to P-cadherin switch can rescue adherens junctions in epithelial tumours. Herein, we disclose a mechanism for E-cadherin to P-cadherin switch in
Externí odkaz:
https://doaj.org/article/c19885064bef47109799dff3020fb63c
Autor:
Ekaterina V. Kravchuk, German A. Ashniev, Marina G. Gladkova, Alexey V. Orlov, Anastasiia V. Vasileva, Anna V. Boldyreva, Alexandr G. Burenin, Artemiy M. Skirda, Petr I. Nikitin, Natalia N. Orlova
Publikováno v:
Cells, Vol 12, Iss 8, p 1191 (2023)
Super-enhancers (SEs) are cis-regulatory elements of the human genome that have been widely discussed since the discovery and origin of the term. Super-enhancers have been shown to be strongly associated with the expression of genes crucial for cell
Externí odkaz:
https://doaj.org/article/07b1d99eacdb4cc4a0df4d5037cad9d7