Zobrazeno 1 - 10
of 774
pro vyhledávání: '"chromatin conformation"'
Autor:
Min He, Xiaoli Li, Bingxiang Xu, Yinbo Lu, Jingyi Lai, Yiming Ling, Huakai Liu, Ziyang An, Wenqing Zhang, Feifei Li
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Background Development of hematopoietic stem and progenitor cells (HSPC) is a multi-staged complex process that conserved between zebrafish and mammals. Understanding the mechanism underlying HSPC development is a holy grail of hematopoietic
Externí odkaz:
https://doaj.org/article/ba26b2da1390471e9b19d42ebc495a25
Autor:
Tavallaee, Ghazaleh, Orouji, Elias ⁎
Publikováno v:
In Computational and Structural Biotechnology Journal 2025 27:89-101
Autor:
Da Lin, Yanyan Zou, Xinyu Li, Jinyue Wang, Qin Xiao, Xiaochen Gao, Fei Lin, Ningyuan Zhang, Ming Jiao, Yu Guo, Zhaowei Teng, Shiyi Li, Yongchang Wei, Fuling Zhou, Rong Yin, Siheng Zhang, Lingyu Xing, Weize Xu, Xiaofeng Wu, Bing Yang, Ke Xiao, Chengchao Wu, Yingfeng Tao, Xiaoqing Yang, Jing Zhang, Sheng Hu, Shuang Dong, Xiaoyu Li, Shengwei Ye, Zhidan Hong, Yihang Pan, Yuqin Yang, Haixiang Sun, Gang Cao
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-20 (2023)
Abstract Genomic abnormalities are strongly associated with cancer and infertility. In this study, we develop a simple and efficient method — multiple genetic abnormality sequencing (MGA-Seq) — to simultaneously detect structural variation, copy
Externí odkaz:
https://doaj.org/article/d9c5fa520aa246c38fef6c8ce42ffe6c
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-14 (2023)
Abstract Background Gene expression has long been known to be influenced by the relative proximity of DNA regulatory elements. Topologically associating domains (TADs) are self-interacting genomic regions involved in regulating gene expression by con
Externí odkaz:
https://doaj.org/article/046a9fe6b9d3493fa641d2f4de3db3db
Autor:
Matthew C. Pahl, Lin Liu, James A. Pippin, Yadav Wagley, Keith Boehm, Kurt D. Hankenson, Andrew D. Wells, Wenli Yang, Struan F.A. Grant
Publikováno v:
EBioMedicine, Vol 101, Iss , Pp 105038- (2024)
Summary: Background: Carpal tunnel syndrome (CTS) is a common disorder caused by compression of the median nerve in the wrist, resulting in pain and numbness throughout the hand and forearm. While multiple behavioural and physiological factors influe
Externí odkaz:
https://doaj.org/article/936e1d8008fc4156b7c5db74b867d0b6
Autor:
Liora S. Katz, Gabriel Brill, Peng Wang, Luca Lambertini, Pili Zhang, Jonathan M. Haldeman, Hongtao Liu, Christopher B. Newgard, Andrew F. Stewart, Adolfo Garcia-Ocaña, Donald K. Scott
Publikováno v:
Molecular Metabolism, Vol 79, Iss , Pp 101848- (2024)
Objective: All forms of diabetes result from insufficient functional β-cell mass. Thus, achieving the therapeutic goal of expanding β-cell mass requires a better mechanistic understanding of how β-cells proliferate. Glucose is a natural β-cell mi
Externí odkaz:
https://doaj.org/article/ca3bb72876334491840e4095754b390d
Publikováno v:
Cellular & Molecular Biology Letters, Vol 28, Iss 1, Pp 1-26 (2023)
Abstract Three-dimensional (3D) genomics is an emerging discipline that studies the three-dimensional structure of chromatin and the three-dimensional and functions of genomes. It mainly studies the three-dimensional conformation and functional regul
Externí odkaz:
https://doaj.org/article/8a47760717be4532b5fbc600b97f043b
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1728-1737 (2023)
Gene regulatory networks are now at the forefront of precision biology, which can help researchers better understand how genes and regulatory elements interact to control cellular gene expression, offering a more promising molecular mechanism in biol
Externí odkaz:
https://doaj.org/article/3003f8564ac6466381350960da82dea5
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Akademický článek
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