Zobrazeno 1 - 10
of 903
pro vyhledávání: '"chromatin architecture"'
Publikováno v:
Epigenetics & Chromatin, Vol 17, Iss 1, Pp 1-13 (2024)
Abstract Background Insulator-binding proteins (IBPs) play a critical role in genome architecture by forming and maintaining contact domains. While the involvement of several IBPs in organising chromatin architecture in Drosophila has been described,
Externí odkaz:
https://doaj.org/article/2603cbab3c9243ada237a07846d5c50f
Autor:
Samuel Rosean, Eric A. Sosa, Dónal O’Shea, Srilakshmi M. Raj, Cathal Seoighe, John M. Greally
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-18 (2024)
Abstract Background As genomic studies continue to implicate non-coding sequences in disease, testing the roles of these variants requires insights into the cell type(s) in which they are likely to be mediating their effects. Prior methods for associ
Externí odkaz:
https://doaj.org/article/4060e01f1a0740f48e1cf9011cdeebb1
Publikováno v:
PeerJ, Vol 12, p e18240 (2024)
The zinc finger protein CTCF is ubiquitously expressed and is integral to the regulation of chromatin architecture through its interaction with cohesin. Conversely, CTCFL expression is predominantly restricted to the adult male testis but is aberrant
Externí odkaz:
https://doaj.org/article/a7a8aac687414a9fb6b07c194921e671
Autor:
Bahaar Chawla, Györgyi Csankovszki
Publikováno v:
DNA, Vol 4, Iss 1, Pp 84-103 (2024)
Chromatin is the complex of DNA and associated proteins found in the nuclei of living organisms. How it is organized is a major research field as it has implications for replication, repair, and gene expression. This review summarizes the current sta
Externí odkaz:
https://doaj.org/article/66064a7107f04ec98978d8e496938d4e
Autor:
Yanli Liu, Zhuqing Zheng, Chaohui Wang, Yumeng Wang, Xi Sun, Zhouzheng Ren, Xin Yang, Xiaojun Yang
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Background Fatty liver disease causes huge economic losses in the poultry industry due to its high occurrence and lethality rate. Three-dimensional (3D) chromatin architecture takes part in disease processing by regulating transcriptional re
Externí odkaz:
https://doaj.org/article/6d04ce502b264b3d9340bbe64eb2e355
Publikováno v:
Nucleus, Vol 15, Iss 1 (2024)
ABSTRACTMost of the genome is transcribed into RNA but only 2% of the sequence codes for proteins. Non-coding RNA transcripts include a very large number of long noncoding RNAs (lncRNAs). A growing number of identified lncRNAs operate in cellular str
Externí odkaz:
https://doaj.org/article/8acae4493f48405193dc0c3f98af9457
Autor:
Atiqur Rahman, Md. Hasan Sofiur Rahman, Md. Shakil Uddin, Naima Sultana, Shirin Akhter, Ujjal Kumar Nath, Shamsun Nahar Begum, Md. Mazadul Islam, Afroz Naznin, Md. Nurul Amin, Sharif Ahmed, Akbar Hossain
Publikováno v:
Journal of Integrative Agriculture, Vol 23, Iss 1, Pp 1-19 (2024)
The impact of epigenetic modifications like DNA methylation on plant phenotypes has expanded the possibilities for crop development. DNA methylation plays a part in the regulation of both the chromatin structure and gene expression, and the enzyme in
Externí odkaz:
https://doaj.org/article/003cb37f7c0a48e9846b6dfab1afcdd2
Autor:
Aria Baniahmad, Mustafa Ozen
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/133d9961bf8c40ab9575d91ced90c712
Autor:
Li Deng, Qiangwei Zhou, Jie Zhou, Qing Zhang, Zhibo Jia, Guangfeng Zhu, Sheng Cheng, Lulu Cheng, Caijun Yin, Chao Yang, Jinxiong Shen, Junwei Nie, Jian-Kang Zhu, Guoliang Li, Lun Zhao
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-30 (2023)
Abstract Background Although spatial organization of compartments and topologically associating domains at large scale is relatively well studied, the spatial organization of regulatory elements at fine scale is poorly understood in plants. Results H
Externí odkaz:
https://doaj.org/article/04c34c22e5ed4651874c861dc3f57f10
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Genomic imprinting is an epigenetic process whereby genes are monoallelically expressed in a parent-of-origin-specific manner. Imprinted genes are frequently found clustered in the genome, likely illustrating their need for both shared regulatory con
Externí odkaz:
https://doaj.org/article/830e3195b57543f98f3c604b36e574b8