Zobrazeno 1 - 10
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pro vyhledávání: '"chromanol 293B"'
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Autor:
Young Hoon Jung, Jun Min Jung, Sang-Ho Ma, Pulla Reddy Boggu, Yeon Su Kim, In Su Kim, Seung Chan Kim
Publikováno v:
Tetrahedron Letters. 61:151431
Stereoselective benzylic amination reaction is important for their further application as pharmaceuticals and agrochemicals, and other chemical entities. Herein, we describe the diastereoselective amination of 1,2-anti-dialkoxychromane on chromane fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fcade33849b7f1c65a514da3d9782f6
https://doi.org/10.1016/j.tetlet.2019.151431
https://doi.org/10.1016/j.tetlet.2019.151431
Publikováno v:
Life Sciences. 76:2275-2286
The effects of chromanol 293B on ion currents in rat embryonic heart-derived H9c2 cells were investigated in this study. Chromanol 293B suppressed the amplitude of delayed rectified K+ current (I(K)) in a concentration-dependent manner. The IC50 valu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82ed3792ea16db180d453517d0e822c7
https://doi.org/10.1016/j.lfs.2004.09.036
https://doi.org/10.1016/j.lfs.2004.09.036
Publikováno v:
Journal of Cardiovascular Pharmacology. 44:192-199
The new anti-anginal drug ranolazine causes a slight (10 milliseconds) prolongation of the QT interval, raising the concern that its use may be associated with an increased incidence of torsades de pointes ventricular tachyarrhythmias. The goal of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::805777c21ad6214d778cf69b63dc6283
https://doi.org/10.1097/00005344-200408000-00008
https://doi.org/10.1097/00005344-200408000-00008
Publikováno v:
Journal of Molecular and Cellular Cardiology. 35:293-300
It is unclear whether chromanol 293B, a selective inhibitor of slow component of delayed rectifier K + current (I K s ), may affect other K + currents in human atrium. With whole-cell patch configuration, we evaluated effects of 293B on transient out
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f548e5045b4884f5d93c0befca398f
https://doi.org/10.1016/s0022-2828(03)00007-5
https://doi.org/10.1016/s0022-2828(03)00007-5
Autor:
Julia C. Senges, Alexander Bauer, Wolfgang Schoels, Patricia Kraft, Kirsten D. Freigang, Wolfgang Kuebler, Frederik Voss, Ruediger Becker
Publikováno v:
Basic Research in Cardiology. 95:324-332
Objectives. Aim of the present study was to investigate site- and rate dependent effects of the IKs-blocking agent chromanol 293b on conduction and refractoriness in normal, infarcted, and transitional regions of in-situ canine hearts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0e15347f4cf3cccf17e36549b0da5c5
https://doi.org/10.1007/s003950070052
https://doi.org/10.1007/s003950070052
Autor:
Ismail Adeniran
Publikováno v:
Modelling the Short QT Syndrome Gene Mutations ISBN: 9783319071992
Variant 2 of the SQTS (SQT2) is associated with gain-of-function mutations to the KCNQ1 protein [1, 2], which when co-expressed with KCNE1 (mink; β-subunit) recapitulates the IKs channel [3, 4] that is partly responsible for repolarization of the ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29dd2fc963ea24d166d809022aee3179
https://doi.org/10.1007/978-3-319-07200-5_7
https://doi.org/10.1007/978-3-319-07200-5_7
Autor:
Jürgen Schreieck, Bernhard Zrenner, Michael Korth, Claus Schmitt, Albert Schömig, Viktor Gjini, Yanggan Wang
Publikováno v:
Journal of Cardiovascular Electrophysiology. 8:1420-1430
Class III Antiarrhythmics and β-Adrenergic Stimulation. Introduction: Blockade of the rapid delayed rectifier potassium current (IKr) as an important mechanism for current Class III antiarrhythmics is less effective in action potential prolongation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9cca2cc597e6cd339fb2189753fdd14
https://doi.org/10.1111/j.1540-8167.1997.tb01039.x
https://doi.org/10.1111/j.1540-8167.1997.tb01039.x
Akademický článek
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