Zobrazeno 1 - 10
of 141
pro vyhledávání: '"christina christoffersen"'
Autor:
Laurie Frances, Mikael Croyal, Soline Pittet, Léa Da Costa Fernandes, Milan Boulaire, Laurent Monbrun, Ellen E. Blaak, Christina Christoffersen, Cédric Moro, Geneviève Tavernier, Nathalie Viguerie
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 10, Pp 100648- (2024)
Obesity is associated with the development of local adipose tissue (AT) and systemic inflammation. Most adipokines are upregulated with obesity and have pro-inflammatory properties. Few are downregulated and possess beneficial anti-inflammatory effec
Externí odkaz:
https://doaj.org/article/dfd513eb38d64fbba5685588168af0de
Autor:
Line S. Bisgaard, Pernille M. Christensen, Jeongah Oh, Federico Torta, Ernst-Martin Füchtbauer, Lars Bo Nielsen, Christina Christoffersen
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Aim: Apolipoprotein M (apoM) is mainly expressed in liver and in proximal tubular epithelial cells in the kidney. In plasma, apoM associates with HDL particles via a retained signal peptide and carries sphingosine-1-phosphate (S1P), a small bioactive
Externí odkaz:
https://doaj.org/article/c632fbff3ec14753b65f60b578dc6773
Autor:
Anna Borup, Ida Donkin, Mariëtte R. Boon, Martin Frydland, Borja Martinez-Tellez, Annika Loft, Sune H. Keller, Andreas Kjaer, Jesper Kjaergaard, Christian Hassager, Romain Barrès, Patrick C. N. Rensen, Christina Christoffersen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract The HDL-associated apolipoprotein M (apoM) and its ligand sphingosine-1-phosphate (S1P) may control energy metabolism. ApoM deficiency in mice is associated with increased vascular permeability, brown adipose tissue (BAT) mass and activity,
Externí odkaz:
https://doaj.org/article/ac928242ef3141f18c4d97ecb075955f
Autor:
Stinne Byrholdt Søgaard, Sofie Bech Andersen, Iman Taghavi, Mikkel Schou, Christina Christoffersen, Jens Christian Brings Jacobsen, Hans Martin Kjer, Carsten Gundlach, Amy McDermott, Jørgen Arendt Jensen, Michael Bachmann Nielsen, Charlotte Mehlin Sørensen
Publikováno v:
Diagnostics, Vol 13, Iss 20, p 3197 (2023)
Individuals with diabetes at risk of developing diabetic kidney disease (DKD) are challenging to identify using currently available clinical methods. Prognostic accuracy and initiation of treatment could be improved by a quantification of the renal m
Externí odkaz:
https://doaj.org/article/3fbb7d0ab6b649e0a015aff6a11fde49
Autor:
Katrine D. Galsgaard, Emilie Elmelund, Christian D. Johansen, Anna B. Bomholt, Hüsün S. Kizilkaya, Frederik Ceutz, Jenna E. Hunt, Hannelouise Kissow, Marie Winther-Sørensen, Charlotte M. Sørensen, Thomas Kruse, Jesper F. Lau, Mette M. Rosenkilde, Cathrine Ørskov, Christina Christoffersen, Jens J. Holst, Nicolai J. Wewer Albrechtsen
Publikováno v:
Molecular Metabolism, Vol 66, Iss , Pp 101639- (2022)
Objective: Treatment with glucagon receptor antagonists (GRAs) reduces blood glucose but causes dyslipidemia and accumulation of fat in the liver. We investigated the acute and chronic effects of glucagon on lipid metabolism in mice. Methods: Chronic
Externí odkaz:
https://doaj.org/article/a7ae536eaac7430393a76a080bee5d30
Autor:
Luke Hall, Chaouri Guo, Sarah Tandy, Kathryn Broadhouse, Anthony C. Dona, Ernst Malle, Emil D. Bartels, Christina Christoffersen, Stuart M. Grieve, Gemma Figtree, Clare L. Hawkins, Michael J. Davies
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract Despite improvements in revascularization after a myocardial infarction, coronary disease remains a major contributor to global mortality. Neutrophil infiltration and activation contributes to tissue damage, via the release of myeloperoxidas
Externí odkaz:
https://doaj.org/article/24ee8bc94a0d461ab1c4070bbfe250ce
Autor:
Ida Maria Hjelm Sørensen, Sasha Asbøll Kepler Saurbrey, Henrik Øder Hjortkjær, Philip Brainin, Nicholas Carlson, Ellen Linnea Freese Ballegaard, Anne-Lise Kamper, Christina Christoffersen, Bo Feldt-Rasmussen, Klaus Fuglsang Kofoed, Susanne Bro
Publikováno v:
BMC Nephrology, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background Patients with chronic kidney disease (CKD) and arterial calcification are considered at increased risk of adverse cardiovascular outcomes. However, the optimal site for measurement of arterial calcification has not been determined
Externí odkaz:
https://doaj.org/article/ee2d1f084ff3413b817b381c8fb21fa2
Autor:
Maria Nicoline Baandrup Kristiansen, Sanne Skovgård Veidal, Christina Christoffersen, Michael Feigh, Niels Vrang, Jonathan David Roth, Mary Erickson, Luciano Adorini, Jacob Jelsing
Publikováno v:
BMC Gastroenterology, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background Compounds in clinical development for nonalcoholic steatohepatitis (NASH) improve liver histopathology in diet-induced obese mouse models of biopsy-confirmed NASH. Since the biopsy section used for histopathological evaluation rep
Externí odkaz:
https://doaj.org/article/e44142f92aa546f5bc09dfe64650bb25
Autor:
Julia T. Stadler, M. N. M. van Poppel, Christina Christoffersen, David Hill, Christian Wadsack, David Simmons, Gernot Desoye, Gunther Marsche, DALI Core Investigator Group
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 68 (2022)
Gestational hypertension (GHTN) is associated with an increased cardiovascular risk for mothers and their offspring later in life. High-density lipoproteins (HDL) are anti-atherogenic by promoting efflux of cholesterol from macrophages and suppressio
Externí odkaz:
https://doaj.org/article/eae7cd87a4db4fe99943d1b33fc9faac
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Kidney disease affects more than 10% of the population, can be both acute and chronic, and is linked to other diseases such as cardiovascular disease, diabetes, and sepsis. Despite the detrimental consequences for patients, no good treatment options
Externí odkaz:
https://doaj.org/article/eb2d508cf59e4f039d4c34a511c46955