Zobrazeno 1 - 10
of 937
pro vyhledávání: '"chrebp"'
Publikováno v:
Animal Cells and Systems, Vol 28, Iss 1, Pp 15-24 (2024)
ABSTRACTGlucose transporter 5 (GLUT5), the main fructose transporter in mammals, is primarily responsible for absorbing dietary fructose in the small intestine. The expression of this intestinal gene significantly increases in response to development
Externí odkaz:
https://doaj.org/article/c7122540d11f487bb98a9cdc28cb8c31
Autor:
Yingying Gong, Meilin Wei, Xiaopei Cao, Changliu Xu, Jiewen Jin, Ling Pei, Yanbing Li, Haipeng Xiao, Liting Wu
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-19 (2024)
Abstract Background Diabetes, a global epidemic, is the leading cause of mortality globally. The aim of this study is to get better understanding of pathophysiology of diabetes. Methods Palmitic acid (PA)-treated β-cells, db/db mice and high fat die
Externí odkaz:
https://doaj.org/article/dd360c6577a842159bec172353d5fa4a
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-18 (2024)
Abstract Objectives Delirium is a prominent symptom of sepsis-associated encephalopathy (SAE) and is highly prevalent in septic patients hospitalized in the intensive care unit, being closely connected with raised mortality rates. Acute hyperglycemia
Externí odkaz:
https://doaj.org/article/71fd1b172929496490ff7f8254c89678
Publikováno v:
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-14 (2024)
Abstract Background Intrahepatic lipid accumulation (IHL), a hallmark of metabolic disorders, is closely associated with de novo lipogenesis (DNL). Notably, fructose feeding increased the DNL. Lifestyle modifications resulting from dietary changes an
Externí odkaz:
https://doaj.org/article/0b7b5284fc514c16b1f331125e192a1e
Publikováno v:
FEBS Open Bio, Vol 14, Iss 11, Pp 1864-1872 (2024)
SNAP25 plays an essential role in the glucose‐stimulated insulin secretion (GSIS) of pancreatic β‐cells. Carbohydrate response element‐binding protein (ChREBP) is an important transcription factor in β‐cells and, in this study, we aimed to
Externí odkaz:
https://doaj.org/article/cc5e687ea1ac43ba97b26fb00930f915
Publikováno v:
Molecular Oncology, Vol 18, Iss 9, Pp 2107-2110 (2024)
Rewiring of cellular metabolism is now fully recognized as a hallmark of cancer. Tumor cells reprogram metabolic pathways to meet the energetic and macromolecular demands to support unrestricted growth and survival under unfavorable conditions. It is
Externí odkaz:
https://doaj.org/article/4357e0c3e3124af3bb2300de6cdfa96b
Akademický článek
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Autor:
Amée M. Buziau, Maaike H. Oosterveer, Kristiaan Wouters, Trijnie Bos, Dean R. Tolan, Loranne Agius, Brian E. Ford, David Cassiman, Coen D.A. Stehouwer, Casper G. Schalkwijk, Martijn C.G.J. Brouwers
Publikováno v:
Molecular Metabolism, Vol 87, Iss , Pp 101984- (2024)
Objective: Stable isotope studies have shown that hepatic de novo lipogenesis (DNL) plays an important role in the pathogenesis of intrahepatic lipid (IHL) deposition. Furthermore, previous research has demonstrated that fructose 1-phosphate (F1P) no
Externí odkaz:
https://doaj.org/article/f788e7cbbd6b437a8180795a7483cdf6
Autor:
Deqiang Zhang, Yuee Zhao, Gary Zhang, Daniel Lank, Sarah Cooke, Sujuan Wang, Alli Nuotio-Antar, Xin Tong, Lei Yin
Publikováno v:
Molecular Metabolism, Vol 85, Iss , Pp 101957- (2024)
Objectives: Compromised hepatic fatty acid oxidation (FAO) has been observed in human MASH patients and animal models of MASLD/MASH. It remains poorly understood how and when the hepatic FAO pathway is suppressed during the progression of MASLD towar
Externí odkaz:
https://doaj.org/article/238fe995bb784466a22f4e4cd8aa092e
Akademický článek
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