Zobrazeno 1 - 10
of 4 680
pro vyhledávání: '"chondrogenic differentiation"'
Publikováno v:
Collagen and Leather, Vol 6, Iss 1, Pp 1-15 (2024)
Abstract The purpose of this study was to investigate the influence of the advanced structure of collagen on the chondrogenic differentiation of BMSCs encapsulated in collagen hydrogels, with an emphasis on MMPs which might affect the cell-material i
Externí odkaz:
https://doaj.org/article/00c2262f46b44271884c56725d691cdd
Autor:
Chen Yijie, Sha Wenqi, Zhang Yifan, Kou Wanyi, Yang Liu, Guo Ruixin, Li Chenyang, Zhao Junjie, Wang Zhenghui
Publikováno v:
Open Medicine, Vol 19, Iss 1, Pp 2041731420943839-73 (2024)
Dysregulation of chondrogenic differentiation is associated with osteoarthritis (OA). The myokine irisin is beneficial in OA treatment; yet, the underlying mechanism is not fully understood. Long noncoding RNAs (lncRNAs) act as important regulators o
Externí odkaz:
https://doaj.org/article/624bdb1b83bf462597faedd180e60c5e
Autor:
Ahreum Baek, Dawoon Baek, Sung Hoon Kim, Jinyoung Kim, Geneva Rose Notario, Do‑Won Lee, Hyun Jung Kim, Sung-Rae Cho
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Osteoarthritis (OA) is a degenerative disease of the joints, prevalent worldwide. Polydeoxyribonucleotide (PDRN) is used for treating knee OA. However, the role of PDRN in IL-1β-induced inflammatory responses in human bone marrow-derived me
Externí odkaz:
https://doaj.org/article/a7e9699ce37440078bd8a02638fd66d3
Publikováno v:
Bioactive Materials, Vol 44, Iss , Pp 220-235 (2025)
Articular cartilage repair and regeneration is still a significant challenge despite years of research. Although microfracture techniques are commonly used in clinical practice, the newborn cartilage is usually fibrocartilage rather than hyaline cart
Externí odkaz:
https://doaj.org/article/2f17f04a1e2f4085967390aaf39b3bb9
Autor:
Ghada Nour Eldeen, Tarek A. Elkhooly, Gehan T. El Bassyouni, Tamer M. Hamdy, Ahmed R. Hawash, Riham M. Aly
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Most of the conditions involving cartilaginous tissues are irreversible and involve degenerative processes. The aim of the present study was to fabricate a biocompatible fibrous and film scaffolds using electrospinning and casting techniques
Externí odkaz:
https://doaj.org/article/a04e934279494f53a7c18be87ac07a3a
Autor:
Xin Wang, Junjun Yang, Rong Wang, Yumengfei Huang, Zu Wan, Zhi Wang, Zhenlan Fu, Cheng Chen, Guangxing Chen, Xiaoyuan Gong
Publikováno v:
Journal of Natural Fibers, Vol 21, Iss 1 (2024)
Mesenchymal stem cells (MSCs) with multipotential differentiation ability are main cell source for cartilage tissue engineering, but its application is restricted by the difficulty in regulating committed chondrogenic differentiation. Study revealed
Externí odkaz:
https://doaj.org/article/a4129e02e0134b269813f74036aeff90
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Background Cartilage is a kind of avascular tissue, and it is difficult to repair itself when it is damaged. In this study, we investigated the regulation of chondrogenic differentiation and vascular formation in human jaw bone marrow mesenc
Externí odkaz:
https://doaj.org/article/720ede090bab4ee6b0927d9e33be5fde
Autor:
Xinyue Zhang, Xue Zhan, Haojin Cheng, Zuqin Dong, Chen Hu, Chenxin Liu, Jie Liang, Yafang Chen, Yujiang Fan, Xingdong Zhang
Publikováno v:
Collagen and Leather, Vol 6, Iss 1, Pp 1-12 (2024)
Abstract The regeneration of articular cartilage posed a formidable challenge due to the restricted treatment efficacy of existing therapies. Scaffold-based tissue engineering emerges as a promising avenue for cartilage reconstitution. However, most
Externí odkaz:
https://doaj.org/article/d2216b0b08a040738ed7ed123c938220
Autor:
Yaylacı Seher
Publikováno v:
Türk Biyokimya Dergisi, Vol 48, Iss 6, Pp 659-667 (2023)
Owing to its avascular nature, cartilage tissue has a restricted capacity for regeneration. These structural features make it difficult for a fully functional tissue to regenerate after damage. Therefore, studies aiming at cartilage tissue regenerati
Externí odkaz:
https://doaj.org/article/76e9158daa6244099353ba955e320fc9
Autor:
Sahar Khajeh, Vahid Razban, Yasaman Naeimzadeh, Elham Nadimi, Reza Asadi-Golshan, Zahra Heidari, Tahereh Talaei-Khozani, Farzaneh Dehghani, Zohreh Mostafavi-Pour, Masoud Shirali
Publikováno v:
Biology, Vol 13, Iss 8, p 560 (2024)
The limited self-repair capacity of articular cartilage is a challenge for healing injuries. While mesenchymal stem/stromal cells (MSCs) are a promising approach for tissue regeneration, the criteria for selecting a suitable cell source remain undefi
Externí odkaz:
https://doaj.org/article/9c75f32932c446f6b51946f2e2e366e9