Zobrazeno 1 - 10
of 226
pro vyhledávání: '"cholinergic signaling"'
Autor:
Lucie Hejnova, Zdenka Drastichova, Almos Boroš, Jaroslav Hrdlicka, Michal Behuliak, Jan Neckar, Josef Zicha, Jiri Novotny
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
BackgroundThe consequences at the molecular level and the mechanisms involved in a possible cardioprotective effect of antihypertensive treatment are not yet fully understood. Here, the efficacy of pyridostigmine (PYR) and trandolapril (TRA) as antih
Externí odkaz:
https://doaj.org/article/4f179291797b43a19147cb6a315b3409
Autor:
Samuel Martínez-Meza, Bhavya Singh, Douglas F. Nixon, Nicholas Dopkins, Louie Mar A. Gangcuangco
Publikováno v:
Bioelectronic Medicine, Vol 9, Iss 1, Pp 1-7 (2023)
Abstract Efferent cholinergic signaling is a critical and targetable source of immunoregulation. The vagus nerve (VN) is the primary source of cholinergic signaling in the body, and partially innervates hepatic functionality through the liver-brain a
Externí odkaz:
https://doaj.org/article/fcd725400adf4e02a782fc6c7a34142b
Autor:
Peter J. Hanley
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Prostatic acid phosphatase (PAP) exists as two splice variants, secreted PAP and transmembrane PAP, the latter of which is implicated in antinociceptive signaling in dorsal root ganglia. However, PAP is predominantly expressed in the prostate gland a
Externí odkaz:
https://doaj.org/article/56b792daa04148988909fdaecc997887
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Karo Talvio, Rimante Minkeviciene, Kayla G. Townsley, Venkat Swaroop Achuta, Laura M. Huckins, Padraic Corcoran, Kristen J. Brennand, Maija L. Castrén
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Lack of FMR1 protein results in fragile X syndrome (FXS), which is the most common inherited intellectual disability syndrome and serves as an excellent model disease to study molecular mechanisms resulting in neuropsychiatric comorbidities. We compa
Externí odkaz:
https://doaj.org/article/5ab2cd00fc1c454d9370f27e857477e5
Autor:
Farbod Amirghasemi, Ali Soleimani, Shahd Bawarith, Asna Tabassum, Alayne Morrel, Maral P. S. Mousavi
Publikováno v:
Bioengineering, Vol 10, Iss 6, p 655 (2023)
Acetylcholine (ACh) is involved in memory and learning and has implications in neurodegenerative diseases; it is therefore important to study the dynamics of ACh in the brain. This work creates a flexible solid-contact potentiometric sensor for in vi
Externí odkaz:
https://doaj.org/article/7971d3dfb19244159f66c1215687da07
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 19, Iss , Pp 100401- (2022)
Inflammatory bowel diseases (IBD) are chronic intestinal disorders characterized by dysregulated immune responses to resident microbiota in genetically susceptible hosts. The activation of the cholinergic system has been proposed for the treatment of
Externí odkaz:
https://doaj.org/article/3e188b7179b94fdaa27417499dee18bd
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-15 (2019)
Abstract Background Nicotinic acetylcholine receptors (nAChRs) are among the oldest and most conserved transmembrane receptors involved in signal transduction. Despite the prevalence and significance of cholinergic signaling, the diversity and evolut
Externí odkaz:
https://doaj.org/article/8a44c02443bb4048a3d9abd09daf7cf5
Autor:
Yasmine Sherafat, Edison Chen, Valeria Lallai, Malia Bautista, James P. Fowler, Yen-Chu Chen, Julie Miwa, Christie D. Fowler
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 15 (2021)
Negative allosteric modulators, such as lynx1 and lynx2, directly interact with nicotinic acetylcholine receptors (nAChRs). The nAChRs are integral to cholinergic signaling in the brain and have been shown to mediate different aspects of cognitive fu
Externí odkaz:
https://doaj.org/article/edc6c13e90ec4498a279928d2d066bb1