Zobrazeno 1 - 10
of 306
pro vyhledávání: '"cholinergic dysfunction"'
Publikováno v:
Heliyon, Vol 10, Iss 20, Pp e39217- (2024)
Alzheimer's disease (AD) is a severe neurodegenerative disorder characterized by the accumulation of β-amyloid (Aβ) plaques and tau phosphorylation-induced neurofibrillary tangles. This review comprehensively summarizes AD pathogenesis and related
Externí odkaz:
https://doaj.org/article/fc7efd181b3f4dce861376b3ba715058
Autor:
Sumin Jeong, Kyu Hwan Shim, Danyeong Kim, Heewon Bae, Da-Eun Jeong, Min Ju Kang, Seong Soo A. An
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
IntroductionParkinson’s disease (PD) is a neurodegenerative disorder characterized by dopaminergic dysfunction and associated with abnormalities in the cholinergic system. However, the relationship between PD and cholinergic dysfunction, particular
Externí odkaz:
https://doaj.org/article/e2b46e49284a4e2d99da1c32898918c2
Autor:
Changjun Lv, Minghui Sun, Yilei Guo, Wenxin Xia, Simiao Qiao, Yu Tao, Yulai Fang, Qin Zhang, Yanrong Zhu, Yusufu Yalikun, Yufeng Xia, Zhifeng Wei, Yue Dai
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 4, Pp 1600-1615 (2023)
Both cholinergic dysfunction and protein citrullination are the hallmarks of rheumatoid arthritis (RA), but the relationship between the two phenomena remains unclear. We explored whether and how cholinergic dysfunction accelerates protein citrullina
Externí odkaz:
https://doaj.org/article/0ae1839ec71e40beb6c5aa11f8d0a80c
Autor:
Ahmed Zubaida Rasheed, Uddin Zaheer, Shah Syed Wadood Ali, Zahoor Muhammad, Alotaibi Amal, Shoaib Mohammad, Ghias Mehreen, Bari Wasim Ul
Publikováno v:
Open Chemistry, Vol 20, Iss 1, Pp 1171-1186 (2022)
In this study, Chenopodium murale Linn. extracts have been evaluated for its in vitro antioxidant, enzyme inhibition, and in vivo neuropharmacological properties in streptozotocin (STZ)-induced memory impairment in rat model. First, the plant was sub
Externí odkaz:
https://doaj.org/article/6d55917beed84ddab332ec7130d2a084
Publikováno v:
BMC Anesthesiology, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Up to 70% of septic patients develop a diffuse brain dysfunction named “septic associated encephalopathy” which is often solely based on clinical impressions. However, the diagnosis of septic associated encephalopathy is outco
Externí odkaz:
https://doaj.org/article/9a4ce8b8c2fd488d966b30571b95eb09
Autor:
Tiantian Qiu, Qingze Zeng, Xiao Luo, Tongcheng Xu, Zhujing Shen, Xiaopei Xu, Chao Wang, Kaicheng Li, Peiyu Huang, Xiaodong Li, Fei Xie, Shouping Dai, Minming Zhang
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Background: Mild cognitive impairment (MCI) is the prodromal phase of Alzheimer’s disease (AD) and has a high risk of progression to AD. Cigarette smoking is one of the important modifiable risk factors in AD progression. Cholinergic dysfunction, e
Externí odkaz:
https://doaj.org/article/c39da36991484a72b5e09bed88231b55
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
The basal forebrain cholinergic system relies on trophic support by nerve growth factor (NGF) to maintain its phenotype and function. In Alzheimer’s disease (AD), basal forebrain cholinergic neurons (BFCNs) undergo progressive atrophy, suggesting a
Externí odkaz:
https://doaj.org/article/06aaa2ea010547b7ae49398e420feaf1
Autor:
Patricia Fernanda Rocha-Dias, Daiane Priscila Simao-Silva, Saritha Suellen Lopes da Silva, Mauro Roberto Piovezan, Ricardo Krause M. Souza, Taher. Darreh-Shori, Lupe Furtado-Alle, Ricardo Lehtonen Rodrigues Souza
Publikováno v:
Genetics and Molecular Biology, Vol 43, Iss 4 (2020)
Abstract The choline acetyltransferase (ChAT) and vesicular acetylcholine transporter (VAChT) are fundamental to neurophysiological functions of the central cholinergic system. We confirmed and quantified the presence of extracellular ChAT protein in
Externí odkaz:
https://doaj.org/article/0322ed7b75cf46bd9bdb58988e88cce5
Autor:
Atiqul Bari, Syed Muhammad Mukarram Shah, Fakhria A. Al-Joufi, Syed Wadood Ali Shah, Mohammad Shoaib, Ismail Shah, Muhammad Zahoor, Muhammad Naeem Ahmed, Mehreen Ghias, Syed Muhammad Hassan Shah, Atif Ali Khan Khalil
Publikováno v:
Molecules, Vol 27, Iss 8, p 2399 (2022)
Different species of Artemisia have been reported to have therapeutic potential in treating various health disorders, including diabetes and memory dysfunction. The present study was planned to evaluate the effects of Artemisia macrocephala Jacquem c
Externí odkaz:
https://doaj.org/article/38d9913d38ad44eb9c4844dd4b67d809
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