Zobrazeno 1 - 10
of 5 081
pro vyhledávání: '"chimeric antigen receptor T"'
Autor:
Jingjing Zhu, Jing Zhang, Ping Wang, Xiuying Liu, Jingjing Liu, Yichao Feng, Mary Yue Jiang, Zhiqiao Feng, Xiaoqing Yao, Jianxun Wang
Publikováno v:
Journal of Traditional Chinese Medical Sciences, Vol 11, Iss 4, Pp 466-475 (2024)
Objective: To investigate the effects and mechanisms of Xuebijing injection (XBJ) on Chimeric antigen receptor-T (CAR-T) cell function and its therapeutic potential against CAR-T therapy-associated cytokine storms (CRS). Methods: Anti-CD19 CAR-T cell
Externí odkaz:
https://doaj.org/article/b9c83cd6dbe04007b856294ef058069a
Autor:
Songnan Sui, Mengjun Zhong, Shuxin Zhong, Xueting Peng, Lipeng Mao, Cunte Chen, Chengwu Zeng, Oscar Junhong Luo, Yangqiu Li
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract Background Exhaustion is a key factor that influences the efficacy of chimeric antigen receptor T (CAR-T) cells. Our previous study demonstrated that a bromodomain protein 4 (BRD4) inhibitor can revise the phenotype and function of exhausted
Externí odkaz:
https://doaj.org/article/4ffb6b26b2d74680b653b6d87757a4c9
Publikováno v:
Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-21 (2024)
Abstract Ovarian cancer, often referred to as the “silent killer,” is notoriously difficult to detect in its early stages, leading to a poor prognosis for many patients. Diagnosis is often delayed until the cancer has advanced, primarily due to i
Externí odkaz:
https://doaj.org/article/27ce0c22a5cb4ddc8eb5304d7b6146e5
Autor:
Orla McCourt, Paul Maciocia, Claire Roddie, Angela Hwang, Leigh Wood, Aikaterini Panopoulou, Deborah Ann Springell, Maise Al Bakir, Maeve O'Reilly
Publikováno v:
eJHaem, Vol 5, Iss 5, Pp 1033-1037 (2024)
Abstract Introduction This report outlines the evaluation of physiotherapist‐led prehabilitation/rehabilitation for recipients of chimeric antigen receptor T (CAR‐T) cell therapy. Methods A hybrid approach was used, incorporating in‐person asse
Externí odkaz:
https://doaj.org/article/6bd3cfb7d68a4538b79ef361cacaa10c
Autor:
Esther Choi, BS, Cuong V. Nguyen, MD
Publikováno v:
JAAD Case Reports, Vol 52, Iss , Pp 42-45 (2024)
Externí odkaz:
https://doaj.org/article/c328054274a048bab92adc7b39b774c4
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Background Chimeric antigen receptor (CAR)-T therapy has emerged as a promising treatment for hematologic malignancies. However, cytopenia remains one of the most frequent and challenging adverse effects of this therapy. Methods We conducted
Externí odkaz:
https://doaj.org/article/d3c85e66332f47c3b2f0ba5e50178e89
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-19 (2024)
Abstract Given its nearly ubiquitous expression on plasma cells and limited expression on essential normal tissue, the G protein-coupled receptor class C group 5 member D (GPRC5D) presents a promising opportunity for utilization as an immunotherapy t
Externí odkaz:
https://doaj.org/article/b4b2d848e2a5405c903b6328a7211437
Autor:
Angela C. Court, Eliseo Parra-Crisóstomo, Pablo Castro-Córdova, Luiza Abdo, Emmanuel Arthur Albuquerque Aragão, Rocío Lorca, Fernando E. Figueroa, Martín Hernán Bonamino, Maroun Khoury
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Apoptosis, a form of programmed cell death, is critical for the development and homeostasis of the immune system. Chimeric antigen receptor T (CAR-T) cell therapy, approved for hematologic cancers, retains several limitations and
Externí odkaz:
https://doaj.org/article/d0d64939ef1b4ab188402484e84e7de2
Publikováno v:
陆军军医大学学报, Vol 46, Iss 17, Pp 1951-1958 (2024)
Objective To use superparamagnetic iron oxide nanoparticles (SPIONs) to label chimeric antigen receptor (CAR) T cells targeting carcinoembryonic antigen (CEA), and perform magnetic resonance imaging (MRI) to real time trace CEA CAR-T cells in vivo. M
Externí odkaz:
https://doaj.org/article/82f0ee9c17b44669b1d55df548b5b1a5
Publikováno v:
陆军军医大学学报, Vol 46, Iss 17, Pp 1959-1968 (2024)
Objective To investigate the feasibility of granzyme B (GB) promoter-controlled ferritin heavy chain (FTH1) reporter gene expression for monitoring the activation status of chimeric antigen receptor T cells (CAR-T) by magnetic resonance imaging (MRI)
Externí odkaz:
https://doaj.org/article/b92548c2f9ce47429828cc255be42a20