Chemotherapy toxicity and activity in patients with pancreatic ductal adenocarcinoma and germline BRCA1-2 pathogenic variants (gBRCA1-2pv): a multicenter survey

Autor: M. Scartozzi, Giampaolo Tortora, Giulia Orsi, Alessandro Cavaliere, Emiliano Tamburini, A.M. Militello, E. Penzo, L.G. Forti, Michele Milella, I. Bernardini, M. Macchini, Silvia Noventa, Michele Reni, M.M. Valente, Monica Niger, Stefano Cascinu, Andrea Spallanzani, K. Bencardino, M. Di Marco, Ingrid Garajová, A. Bittoni, U. Peretti, S. Mosconi, Silvia Bozzarelli, Maria Grazia Rodriquenz, C. Paratore, I.G. Rapposelli, Guido Giordano, S. De Lorenzo, Elisa Giommoni

Publikováno v: ESMO Open

Background Germline BRCA1-2 pathogenic variants (gBRCA1-2pv)-related pancreatic ductal adenocarcinoma (PDAC) showed increased sensitivity to DNA cross-linking agents. This study aimed at exploring safety profile, dose intensity, and activity of diffe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c3d6ecae6dfd5240f9890e44c4b137

Prognostic factors affecting long-term outcomes in patients with resected stage IIIA pN2 non-small-cell lung cancer: 5-year follow-up of a phase II study

Autor: Miklos Pless, R. Stahel, Anastase Spiliopoulos, Markus Furrer, Arnaud Roth, C. Von Briel, James Habicht, M. Wernli, Eva Hansen, Ralph A. Schmid, Martin Tötsch, Christine Joss, Fritz Egli, Hanspeter Honegger, H-B Ris, Thomas Cerny, Daniel C. Betticher, W. Weder, S-F Hsu Schmitz, Roger Stupp

Publikováno v: British journal of cancer, vol. 94, no. 8, pp. 1099-106
British Journal of Cancer, Vol. 94, No 8 (2006) pp. 1099-106
British Journal of Cancer

The aim was to investigate the efficacy of neoadjuvant docetaxel–cisplatin and identify prognostic factors for outcome in locally advanced stage IIIA (pN2 by mediastinoscopy) non-small-cell lung cancer (NSCLC) patients. In all, 75 patients (from 90

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3dc1cf64797ae33965e63698aaee81f
https://doi.org/10.1038/sj.bjc.6603075

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.