Zobrazeno 1 - 10
of 2 356
pro vyhledávání: '"chemoreflex"'
Publikováno v:
Experimental Physiology, Vol 109, Iss 11, Pp 1837-1843 (2024)
Abstract At least four mechanisms have been proposed to elucidate how neurons in the retrotrapezoid (RTN) region sense changes in CO2/H+ to regulate breathing (i.e., function as respiratory chemosensors). These mechanisms include: (1) intrinsic neuro
Externí odkaz:
https://doaj.org/article/103fef083f814eb282d57d762242af60
Autor:
Savannah Lusk, Alexander M. Moushey, Nicholas Iwakoshi, Christopher G. Wilson, Aihua Li, Russell Ray
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
An overactive orexin (OX) system is associated with neurogenic hypertension and an exaggerated chemoreflex in spontaneously hypertensive rats (SHRs). However, the chronology and mechanism of this association is unclear. We hypothesized that increased
Externí odkaz:
https://doaj.org/article/cdf1e4feacbc45ff8801a0c93b1096a8
Autor:
Anna M. Gonsalves, Sarah E. Baker, Dain W. Jacob, Jennifer L. Harper, Camila M. Manrique‐Acevedo, Jacqueline K. Limberg
Publikováno v:
Physiological Reports, Vol 12, Iss 17, Pp n/a-n/a (2024)
Abstract Endothelin‐1 (ET‐1) and its receptors are linked to increases in sensitivity of the chemoreceptors to hypoxic stress and the development of hypertension in preclinical models. We hypothesized ET receptor antagonism would lower resting bl
Externí odkaz:
https://doaj.org/article/e026846d30c449f5a3ad217d52f3d2aa
Chemoreflex sensitization occurs in both male and female rats during recovery from acute lung injury
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
IntroductionSex-specific patterns in respiratory conditions, such as asthma, COPD, cystic fibrosis, obstructive sleep apnea, and idiopathic pulmonary fibrosis, have been previously documented. Animal models of acute lung injury (ALI) have offered ins
Externí odkaz:
https://doaj.org/article/fd7dd7b4eba84004b095f96425f9fb0c
Autor:
Benjamin R. O'Croinin, Desmond A. Young, Lauren E. Maier, Sean vanDiepen, Trevor A. Day, Craig D. Steinback
Publikováno v:
Physiological Reports, Vol 12, Iss 11, Pp n/a-n/a (2024)
Abstract We aimed to determine the relative contribution of hypercapnia and hypoxia to the bradycardic response to apneas. We hypothesized that apneas with hypercapnia would cause greater bradycardia than normoxia, similar to the response seen with h
Externí odkaz:
https://doaj.org/article/e940d6b120a740ba93863be01ae593f2
Autor:
Pablo Alvarez-Araos, Sergio Jiménez, Camila Salazar-Ardiles, Cristian Núñez-Espinosa, Valeria Paez, Maria Rodriguez-Fernandez, Antoine Raberin, Gregoire P. Millet, Rodrigo Iturriaga, David C. Andrade
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
The hypoxic chemoreflex and the arterial baroreflex are implicated in the ventilatory response to exercise. It is well known that long-term exercise training increases parasympathetic and decreases sympathetic tone, both processes influenced by the a
Externí odkaz:
https://doaj.org/article/3c02fe299b584e978abf36e67808bf9a
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Autor:
Esteban Díaz-Jara, Katherine Pereyra, Sinay Vicencio, Margrethe A. Olesen, Karla G. Schwarz, Camilo Toledo, Hugo S. Díaz, Rodrigo A. Quintanilla, Rodrigo Del Rio
Publikováno v:
Redox Biology, Vol 69, Iss , Pp 102992- (2024)
Aims: In mammals, central chemoreception plays a crucial role in the regulation of breathing function in both health and disease conditions. Recently, a correlation between high levels of superoxide anion (O2.-) in the Retrotrapezoid nucleus (RTN), a
Externí odkaz:
https://doaj.org/article/6ba38921a7294a5c9e6a4d0245de337d
Autor:
David C. Andrade, Alexis Arce‐Álvarez, Camila Salazar‐Ardiles, Camilo Toledo, Juan Guerrero‐Henriquez, Cristian Alvarez, Manuel Vasquez‐Muñoz, Mikel Izquierdo, Gregoire P. Millet
Publikováno v:
Physiological Reports, Vol 12, Iss 1, Pp n/a-n/a (2024)
Abstract Swimmer athletes showed a decreased ventilatory response and reduced sympathetic activation during peripheral hypoxic chemoreflex stimulation. Based on these observations, we hypothesized that swimmers develop a diminished cardiorespiratory
Externí odkaz:
https://doaj.org/article/cda8ff8d2fef463098b6e8609cb98a4b
Autor:
Stanislaw Tubek, Piotr Niewinski, Anna Langner-Hetmanczuk, Maksym Jura, Wiktor Kuliczkowski, Krzysztof Reczuch, Piotr Ponikowski
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: The most common side effect of ticagrelor is dyspnea, which leads to premature withdrawal of this life-saving medication in 6.5% of patients. Increased chemoreceptors’ sensitivity was suggested as a possible pathophysiological explana
Externí odkaz:
https://doaj.org/article/1927d4086e0a4d748448c22da4c5c7fa