Zobrazeno 1 - 10
of 39
pro vyhledávání: '"chemokine signalling"'
Autor:
Eveline M. Ibeagha-Awemu, Nathalie Bissonnette, Duy N. Do, Pier-Luc Dudemaine, Mengqi Wang, Antonio Facciuolo, Philip Griebel
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Mycobacterium avium subsp. paratuberculosis (MAP) is the causative infectious agent of Johne’s disease (JD), an incurable granulomatous enteritis affecting domestic livestock and other ruminants around the world. Chronic MAP infections usually begi
Externí odkaz:
https://doaj.org/article/0743af879b1a478b9e0a98374cf09ccd
Autor:
Yoko Tsukita, Naoya Fujino, Eisaku Miyauchi, Ryoko Saito, Fumiyoshi Fujishima, Koji Itakura, Yorihiko Kyogoku, Koji Okutomo, Mitsuhiro Yamada, Tatsuma Okazaki, Hisatoshi Sugiura, Akira Inoue, Yoshinori Okada, Masakazu Ichinose
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-6 (2019)
Abstract Axl receptor tyrosine kinase is involved in the growth and metastasis and is an indicator of poor prognosis in several cancers including lung cancers. Although a mitogen-activated protein kinase (MAPK) pathway and an epithelial-to-mesenchyma
Externí odkaz:
https://doaj.org/article/93e14b7c7c854a09bfda1b3a7027591b
Publikováno v:
eLife, Vol 7 (2018)
Chemokines are secreted proteins that regulate a range of processes in eukaryotic organisms. Interestingly, different chemokine receptors control distinct biological processes, and the same receptor can direct different cellular responses, but the ba
Externí odkaz:
https://doaj.org/article/6e470326b85645bd9ab4eba9d760fa76
Autor:
Jonna Alanko, Michael Sixt
Publikováno v:
eLife, Vol 7 (2018)
In zebrafish larvae, it is the cell type that determines how the cell responds to a chemokine signal.
Externí odkaz:
https://doaj.org/article/557257af5df44608a4c168074fd99404
Autor:
Monica Varela, Annemarie H. Meijer
Publikováno v:
Molecular Microbiology
Molecular Microbiology, 117(3), 661-669. Wiley
Molecular Microbiology, 117(3), 661-669. Wiley
The zebrafish has earned its place among animal models to study tuberculosis and other infections caused by pathogenic mycobacteria. This model host is especially useful to study the role of granulomas, the inflammatory lesions characteristic of myco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09f5f2126f1ae27c0bed56c051b3d9d8
http://hdl.handle.net/1887/3256818
http://hdl.handle.net/1887/3256818
Autor:
Graham K Sheridan, Anita eWdowicz, Mark ePickering, Orla eWatters, Paul eHalley, Niamh eO'Sullivan, Claire eMooney, David J O'Connell, John J O'Connor, Keith J Murphy
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 8 (2014)
Several cytokines and chemokines are now known to play normal physiological roles in the brain where they act as key regulators of communication between neurons, glia and microglia. In particular, cytokines and chemokines can affect cardinal cellular
Externí odkaz:
https://doaj.org/article/69472af6fba742ddb8429bfdcbe8880a
Akademický článek
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Autor:
Yorihiko Kyogoku, Ryoko Saito, Yoshinori Okada, Koji Okutomo, Yoko Tsukita, Akira Inoue, Tatsuma Okazaki, Hisatoshi Sugiura, Naoya Fujino, Masakazu Ichinose, Eisaku Miyauchi, Mitsuhiro Yamada, Fumiyoshi Fujishima, Koji Itakura
Publikováno v:
Molecular Cancer
Molecular Cancer, Vol 18, Iss 1, Pp 1-6 (2019)
Molecular Cancer, Vol 18, Iss 1, Pp 1-6 (2019)
Axl receptor tyrosine kinase is involved in the growth and metastasis and is an indicator of poor prognosis in several cancers including lung cancers. Although a mitogen-activated protein kinase (MAPK) pathway and an epithelial-to-mesenchymal transit
Autor:
Klaus Kallenbach, Bernd Timmermann, Peter N. Robinson, Yunxiang Zhu, Lukas Altinbas, Georgios Kararigas, Nicholas P. Clayton, Daniel Lehmann, Marcin Zaradzki, Marten Jäger, Raghu Bhushan
Publikováno v:
Journal of Cellular and Molecular Medicine
Marfan syndrome (MFS) is an autosomal dominant genetic disorder caused by mutations in the FBN1 gene. Although many peripheral tissues are affected, aortic complications, such as dilation, dissection and rupture, are the leading causes of MFS‐relat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57401563790c9b6a43fc71517dd8cd4d
https://hdl.handle.net/21.11116/0000-0003-7950-B21.11116/0000-0003-7952-9
https://hdl.handle.net/21.11116/0000-0003-7950-B21.11116/0000-0003-7952-9
Autor:
Kelly, Christopher James
Publikováno v:
IndraStra Global.
Inflammatory chemokine signalling is implicated in a broad range of pathologies and has been intensely researched. However, chemokine receptors remain poorly druggable. This may be due to the complexity of chemokine signalling; multiple chemokines ca