Zobrazeno 1 - 10
of 310
pro vyhledávání: '"chaperone system"'
Autor:
Charbel A. Basset, Inaya Hajj Hussein, Abdo R. Jurjus, Francesco Cappello, Everly Conway de Macario, Alberto J. L. Macario, Angelo Leone
Publikováno v:
Applied Biosciences, Vol 2, Iss 4, Pp 607-616 (2023)
The chaperone system (CS) is emerging as a key multistage participant in carcinogenesis. The CS chief components are the molecular chaperones (some of which are named heat shock proteins or Hsp), which are typically cytoprotective but if abnormal in
Externí odkaz:
https://doaj.org/article/90adff64b78b468a8aa2dff30115eb3a
Autor:
Giuseppa D’Amico, Radha Santonocito, Godfrey Grech, Giuseppa Graceffa, Calogero Cipolla, Federica Scalia, Samuele Raccosta, Mauro Manno, Everly Conway de Macario, Alberto J. L. Macario, Francesco Cappello, Francesca Rappa, Celeste Caruso Bavisotto, Claudia Campanella
Publikováno v:
Biology, Vol 13, Iss 9, p 743 (2024)
Background: The incidence of various types of cancer, for example, papillary thyroid carcinoma (PTC), is on the rise. Since therapeutic success depends greatly on early diagnosis, reliable diagnostic biomarkers must be identified, and easy-to-apply t
Externí odkaz:
https://doaj.org/article/11d8219f73944c1fa34e59a432591f56
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-20 (2023)
Abstract Background Unidirectional regeneration in the basal chordate Ciona intestinalis involves the proliferation of adult stem cells residing in the branchial sac vasculature and the migration of progenitor cells to the site of distal injury. Howe
Externí odkaz:
https://doaj.org/article/32bba2fa0937484aaaa486bdd89bfe37
Autor:
Leila Noori, Vahid Saqagandomabadi, Valentina Di Felice, Sabrina David, Celeste Caruso Bavisotto, Fabio Bucchieri, Francesco Cappello, Everly Conway de Macario, Alberto J. L. Macario, Federica Scalia
Publikováno v:
Cells, Vol 13, Iss 3, p 217 (2024)
The putative pathogenic roles and therapeutic potential of the chaperone system (CS) in amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS) are reviewed to provide a bibliographic and conceptual platform for launching research on the diag
Externí odkaz:
https://doaj.org/article/45e2a572e6844b43bb791f1b6cbbab34
Autor:
Alessandro Pitruzzella, Alberto Fucarino, Michele Domenico Modica, Vincenzo Luca Lentini, Claudio Vella, Stefano Burgio, Federica Calabrò, Giorgia Intili, Francesca Rappa
Publikováno v:
Applied Sciences, Vol 14, Iss 2, p 722 (2024)
Laryngeal squamous cell carcinoma (LSCC) constitutes a noteworthy subset of head and neck cancers, contributing to about 4.5% of all malignancies. Its clinical behavior and characteristics exhibit variations contingent upon the specific anatomical si
Externí odkaz:
https://doaj.org/article/6e995936c3a04f8e908015c059ed3e3f
Autor:
Letizia Paladino, Francesca Rappa, Rosario Barone, Filippo Macaluso, Francesco Paolo Zummo, Sabrina David, Marta Anna Szychlinska, Fabio Bucchieri, Everly Conway de Macario, Alberto J. L. Macario, Francesco Cappello, Antonella Marino Gammazza
Publikováno v:
Biology, Vol 12, Iss 11, p 1394 (2023)
Probiotics are live microorganisms that yield health benefits when consumed, generally by improving or restoring the intestinal flora (microbiota) as part of the muco-microbiotic layer of the bowel. In this work, mice were fed with ethanol alone or i
Externí odkaz:
https://doaj.org/article/2ab33950ab874359b77ffc9aa1916d1c
Akademický článek
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Autor:
Federica Scalia, Rosario Barone, Francesca Rappa, Antonella Marino Gammazza, Fabrizio Lo Celso, Giosuè Lo Bosco, Giampaolo Barone, Vincenzo Antona, Maria Vadalà, Alessandra Maria Vitale, Giuseppe Donato Mangano, Domenico Amato, Giusy Sentiero, Filippo Macaluso, Kathryn H. Myburgh, Everly Conway de Macario, Alberto J. L. Macario, Mario Giuffrè, Francesco Cappello
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Recognition of diseases associated with mutations of the chaperone system genes, e.g., chaperonopathies, is on the rise. Hereditary and clinical aspects are established, but the impact of the mutation on the chaperone molecule and the mechanisms unde
Externí odkaz:
https://doaj.org/article/cd1625c7ed9143f88ed56f2839b5078d
Autor:
Federica Scalia, Everly Conway de Macario, Giuseppe Bonaventura, Francesco Cappello, Alberto J. L. Macario
Publikováno v:
Biology, Vol 12, Iss 5, p 641 (2023)
Genetic chaperonopathies are rare but, because of misdiagnosis, there are probably more cases than those that are recorded in the literature and databases. This occurs because practitioners are generally unaware of the existence and/or the symptoms a
Externí odkaz:
https://doaj.org/article/1ca4a0982f5c47229e61efc5a8e6a408
Akademický článek
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