Zobrazeno 1 - 10
of 543
pro vyhledávání: '"channel conductance"'
Autor:
Ishan Ghai
Publikováno v:
Membranes, Vol 14, Iss 7, p 161 (2024)
The alarming rise of antibiotic resistance in Gram-negative bacteria has emerged as a major global health challenge. A key factor contributing to this crisis is the low permeability of the bacterial outer membrane, which acts as a barrier that preven
Externí odkaz:
https://doaj.org/article/39fddd93592041438a7fd0bf69cf821b
Autor:
David Naranjo, Ignacio Diaz-Franulic
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Because they enable for the modification of both viscosity and osmolarity, sugars have been used as a biophysical probe of voltage-gated K-channels for a while. Viscosity variations made it possible to measure the pore sizes in large and small conduc
Externí odkaz:
https://doaj.org/article/494b129423904c0eac80801d51b0b1de
Autor:
Federico Miguez-Cabello, Nuria Sánchez-Fernández, Natalia Yefimenko, Xavier Gasull, Esther Gratacòs-Batlle, David Soto
Publikováno v:
eLife, Vol 9 (2020)
AMPARs control fast synaptic communication between neurons and their function relies on auxiliary subunits, which importantly modulate channel properties. Although it has been suggested that AMPARs can bind to TARPs with variable stoichiometry, littl
Externí odkaz:
https://doaj.org/article/93bff999dbfe4032ba9add5b43108de9
Autor:
Pippel, Anja, Stolz, Michaela, Woltersdorf, Ronja, Kless, Achim, Schmalzing, Günther, Markwardt, Fritz
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2017 Mar . 114(11), E2156-E2165.
Externí odkaz:
https://www.jstor.org/stable/26480292
Autor:
Phale, Prashant S., Schirmer, Tilman, Prilipov, Alexej, Lou, Kuo-Long, Hardmeyer, Ariane, Rosenbusch, Jurg P.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1997 Jun . 94(13), 6741-6745.
Externí odkaz:
https://www.jstor.org/stable/42222
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 20; Pages: 12124
We describe genetic and molecular-level functional alterations in the α4β2 neuronal nicotinic acetylcholine receptor (nAChR) from a patient with sleep-related hyperkinetic epilepsy and a family history of epilepsy. Genetic sequencing revealed a het
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11605
Lens gap junctions (GJs) formed by Cx46 and Cx50 are important to keep lens transparency. Functional studies on Cx46 and Cx50 GJs showed that the Vj-gating, single channel conductance (γj), gating polarity, and/or channel open stability could be mod
Akademický článek
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Akademický článek
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Autor:
Vardha Ismail, Linda G. Zachariassen, Annie Godwin, Mane Sahakian, Sian Ellard, Karen L. Stals, Emma Baple, Kate Tatton Brown, Nicola Foulds, Gabrielle Wheway, Matthew O. Parker, Signe M. Lyngby, Miriam G. Pedersen, Julie Desir, Allan Bayat, Maria Musgaard, Matthew Guille, Anders S. Kristensen, Diana Baralle
Publikováno v:
Ismail, V, Zachariassen, L G, Godwin, A, Sahakian, M, Ellard, S, Stals, K L, Baple, E, Brown, K T, Foulds, N, Wheway, G, Parker, M O, Lyngby, S M, Pedersen, M G, Desir, J, Bayat, A, Musgaard, M, Guille, M, Kristensen, A S & Baralle, D 2022, ' Identification and functional evaluation of GRIA1 missense and truncation variants in individuals with ID : An emerging neurodevelopmental syndrome ', American Journal of Human Genetics, vol. 109, no. 7, pp. 1217-1241 . https://doi.org/10.1016/j.ajhg.2022.05.009
GRIA1 encodes the GluA1 subunit of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors, which are ligand-gated ion channels that act as excitatory receptors for the neurotransmitter L-glutamate (Glu). AMPA receptors (AMPARs) are ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2447239acb651f58a52c081710ba7e50
https://curis.ku.dk/portal/da/publications/identification-and-functional-evaluation-of-gria1-missense-and-truncation-variants-in-individuals-with-id(9576e283-94cc-4daf-91c3-e74d23a8b35f).html
https://curis.ku.dk/portal/da/publications/identification-and-functional-evaluation-of-gria1-missense-and-truncation-variants-in-individuals-with-id(9576e283-94cc-4daf-91c3-e74d23a8b35f).html