Zobrazeno 1 - 10
of 779
pro vyhledávání: '"challenge model"'
Autor:
Kurhaluk Natalia, Grudniewska Joanna, Pękala-Safińska Agnieszka, Pajdak-Czaus Joanna, Terech-Majewska Elżbieta, Platt-Samoraj Aleksandra, Tkaczenko Halina
Publikováno v:
Journal of Veterinary Research, Vol 68, Iss 3, Pp 325-336 (2024)
This study aimed to evaluate biomarkers of oxidative stress (2-thiobarbituric acid reactive substances, aldehyde and ketone derivatives of oxidatively modified proteins and total antioxidant capacity), the activity of antioxidant enzymes (superoxide
Externí odkaz:
https://doaj.org/article/b402b34759674097a581921ab4b70b67
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Controlled human infection model (CHIM) studies, which involve deliberate exposure of healthy human volunteers to an infectious agent, are recognised as important tools to advance vaccine development. These studies not only facilitate estimates of va
Externí odkaz:
https://doaj.org/article/32cc227c4dfb4ad986ac304aa2939c23
Autor:
Xiaohui Wei, Jing Wu, Wanjun Peng, Xin Chen, Lihong Zhang, Na Rong, Hekai Yang, Gengxin Zhang, Gaoying Zhang, Binbin Zhao, Jiangning Liu
Publikováno v:
Vaccines, Vol 12, Iss 6, p 570 (2024)
Hand, foot, and mouth disease (HFMD) is a contagious viral infection predominantly affecting infants and young children, caused by multiple enteroviruses, including Enterovirus 71 (EV71), Coxsackievirus A16 (CA16), Coxsackievirus A10 (CA10), and Coxs
Externí odkaz:
https://doaj.org/article/dd1f44f69d4a4d2db4807a2c418a087d
Publikováno v:
Berliner und Münchener Tierärztliche Wochenschrift, Vol 136 (2023)
The objective of the trials was to test the efficacy of a Clostridium perfringens type A toxoid vaccine with a toxin challenge model and under field conditions according to Regulation (EU) 2019/6.15 gilts were vaccinated twice at 5 and 2 weeks before
Externí odkaz:
https://doaj.org/article/1978f8e6171a4749a8e4bbd1e48d4c3d
Autor:
James E. Meiring, Emma Smith, Peter W.S. Hill, Malick M. Gibani, Megan E. Carey, Christopher Chiu, Melita Gordon, Graham Cooke, Thomas C. Darton, Jay Hinton, Christopher Smith, Robert K.M. Choy, Blanca Perez Sepulveda
Publikováno v:
Wellcome Open Research, Vol 8 (2023)
Invasive non-typhoidal Salmonella disease (iNTS) is a major cause of morbidity and mortality globally, particularly as a cause of bloodstream infection in children and immunocompromised adults in sub-Saharan Africa. Vaccines to prevent non-typhoidal
Externí odkaz:
https://doaj.org/article/1feb40961b6541d49ab39f6dd848833b
Publikováno v:
Journal of Dairy Science, Vol 106, Iss 2, Pp 1453-1463 (2023)
ABSTRACT: Intestinal hyperpermeability and subsequent immune activation alters nutrient partitioning and thus, decreases productivity. Developing experimental models of intestinal barrier dysfunction in heathy cows is a prerequisite in identifying nu
Externí odkaz:
https://doaj.org/article/017f7029f5d240099a171fbf24d3156b
Autor:
Danielle Graham, Victor M. Petrone-Garcia, Xochitl Hernandez-Velasco, Makenly E. Coles, Marco A. Juarez-Estrada, Juan D. Latorre, Jianmin Chai, Stephanie Shouse, Jiangchao Zhao, Aaron J. Forga, Roberto Senas-Cuesta, Lauren Laverty, Kristen Martin, Carolina Trujillo-Peralta, Ileana Loeza, Latasha S. Gray, Billy M. Hargis, Guillermo Tellez-Isaias
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
A mixed Eimeria spp. challenge model was designed to assess the effects of challenge on broiler chicken performance, intestinal integrity, and the gut microbiome for future use to evaluate alternative strategies for controlling coccidiosis in broiler
Externí odkaz:
https://doaj.org/article/83390a32ea354a0294ac863b224cad9c
Autor:
Gry Persson, Katherine H. Restori, Julie Hincheli Emdrup, Sophie Schussek, Michael Schantz Klausen, McKayla J. Nicol, Bhuvana Katkere, Birgitte Rønø, Girish Kirimanjeswara, Anders Bundgaard Sørensen
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The global SARS-CoV-2 pandemic caused significant social and economic disruption worldwide, despite highly effective vaccines being developed at an unprecedented speed. Because the first licensed vaccines target only single B-cell antigens, antigenic
Externí odkaz:
https://doaj.org/article/7c3ec6d2deec481cb87d29f2d08db6ea
Autor:
Shimeng Bai, Tianhan Yang, Cuisong Zhu, Meiqi Feng, Li Zhang, Ziling Zhang, Xiang Wang, Rui Yu, Xinghao Pan, Chen Zhao, Jianqing Xu, Xiaoyan Zhang
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/a61f6896e7ec420388a4e82cc0417c58
Autor:
Shimeng Bai, Tianhan Yang, Cuisong Zhu, Meiqi Feng, Li Zhang, Ziling Zhang, Xiang Wang, Rui Yu, Xinghao Pan, Chen Zhao, Jianqing Xu, Xiaoyan Zhang
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
BackgroundRabies is a lethal zoonotic disease that kills approximately 60,000 people each year. Although inactivated rabies vaccines are available, multiple-dose regimensare recommended for pre-exposure prophylaxis or post-exposure prophylaxis,which
Externí odkaz:
https://doaj.org/article/da7f89c5a61e4520aa0f8f689d3fc251