Zobrazeno 1 - 10
of 3 637
pro vyhledávání: '"cfDNA"'
Autor:
Alessandro Mannucci, Ajay Goel
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-25 (2024)
Abstract Background Biomarkers have revolutionized the management of colorectal cancer (CRC), facilitating early detection, prevention, personalized treatment, and minimal residual disease (MRD) monitoring. This review explores current CRC screening
Externí odkaz:
https://doaj.org/article/2a37f2631a18496b881921b3381f7032
Autor:
Guochao Zhao, Ruijingfang Jiang, Ying Shi, Suizhi Gao, Dansong Wang, Zhilong Li, Yuhong Zhou, Jianlong Sun, Wenchuan Wu, Jiaxi Peng, Tiantao Kuang, Yefei Rong, Jie Yuan, Shida Zhu, Gang Jin, Yuying Wang, Wenhui Lou
Publikováno v:
Molecular Oncology, Vol 18, Iss 11, Pp 2801-2813 (2024)
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with a 5‐year survival rate of 7.2% in China. However, effective approaches for diagnosis of PDAC are limited. Tumor‐originating genomic and epigenomic aberration in circulatin
Externí odkaz:
https://doaj.org/article/b094acad6c084888b80b80a3f9b3b75d
Autor:
Kerstin Clasen, Cihan Gani, Leon Schuetz, Stephan Clasen, Nadja Ballin, Irina Bonzheim, Michael Orth, Stephan Ossowski, Olaf Riess, Maximilian Niyazi, Christopher Schroeder, Olga Kelemen
Publikováno v:
Radiation Oncology, Vol 19, Iss 1, Pp 1-9 (2024)
Abstract Background In locally advanced rectal cancer, the prediction of tumor response during and after neoadjuvant treatment remains challenging. In terms of organ preservation, adaptive radiotherapy, and intensified (total) neoadjuvant therapies,
Externí odkaz:
https://doaj.org/article/b87efb56e9eb484882e6753ca92a7eed
Autor:
Valeria Pessei, Marco Macagno, Elisa Mariella, Noemi Congiusta, Vittorio Battaglieri, Paolo Battuello, Marco Viviani, Giulia Gionfriddo, Simona Lamba, Annalisa Lorenzato, Daniele Oddo, Fariha Idrees, Alessandro Cavaliere, Alice Bartolini, Simonetta Guarrera, Michael Linnebacher, Laura Monteonofrio, Luca Cardone, Michele Milella, Andrea Bertotti, Silvia Soddu, Elena Grassi, Giovanni Crisafulli, Alberto Bardelli, Ludovic Barault, Federica Di Nicolantonio
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background Liquid biopsy based on cell-free DNA (cfDNA) analysis holds significant promise as a minimally invasive approach for the diagnosis, genotyping, and monitoring of solid malignancies. Human tumors release cfDNA in the bloodstream th
Externí odkaz:
https://doaj.org/article/769e6f9e67d94058a19f60e264b16a42
Autor:
Haiqiang Zhang, Lingguo Li, Yuxue Luo, Fang Zheng, Yan Zhang, Rong Xie, Rijing Ou, Yilin Chen, Yu Lin, Yeqin Wang, Yan Jin, Jinjin Xu, Ye Tao, Ruokai Qu, Wenwen Zhou, Yong Bai, Fanjun Cheng, Xin Jin
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-13 (2024)
Abstract Background The mortality rate of COVID-19 patients with critical symptoms is reported to be 40.5%. Early identification of patients with poor progression in the critical cohort is essential to timely clinical intervention and reduction of mo
Externí odkaz:
https://doaj.org/article/d322779e308341feb43d5899e6cc1fb2
Publikováno v:
Медицинская иммунология, Vol 26, Iss 5, Pp 1025-1030 (2024)
Schizophrenia is a mental illness of complex etiology. Recently, there has been increased interest in the role of the immune system in the pathophysiology of mental disorders. The concept of neuroinflammation in neurodevelopmental disorders is gainin
Externí odkaz:
https://doaj.org/article/c47c5264e16846c68071ef77db79e212
Autor:
Hongchao Du, Wenfeng Liu, Yunfei Li, Lijuan Zhang, Fangfang Jiang, Dandan Zhu, Jingshuai Li, Pan Hu, Ningning Yan, Mao Mao, Shiyong Li
Publikováno v:
BMC Research Notes, Vol 17, Iss 1, Pp 1-7 (2024)
Abstract Objective Cancer is currently the most common cause of death in adult dogs. Like humans, dogs have a one-third chance of developing cancer in their lifetime. We used shallow whole-genome sequencing (sWGS) to analyze blood cell-free DNA (cfDN
Externí odkaz:
https://doaj.org/article/aef2f4e8c20f451cb58153809a56d8e6
Publikováno v:
Indian Journal of Pathology and Microbiology, Vol 67, Iss 3, Pp 492-501 (2024)
Current advances in the understanding of the lung cancer landscape have drastically changed the approach to treating a patient with lung carcinoma. The field has progressed from analyzing single gene to using advanced techniques like next-generation
Externí odkaz:
https://doaj.org/article/7eec3fbec96f48c9a529e43f3d558b5e
Autor:
Jing Liu, Dan Hu, Yibin Lin, Xiaoxi Chen, Ruowei Yang, Li Li, Yanyan Zhan, Hua Bao, LeLe Zang, Mingxuan Zhu, Fei Zhu, Junrong Yan, Dongqin Zhu, Huiqi Zhang, Benhua Xu, Qin Xu
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Uterine corpus endometrial carcinoma (UCEC) is a prevalent gynecologic malignancy with a favorable prognosis if detected early. However, there is a lack of accurate and reliable early detection tests for UCEC. This study aims to d
Externí odkaz:
https://doaj.org/article/0c6edec07a89463fa804f34ffe429ca8
Autor:
Dalin Xiong, Tiancheng Han, Yulong Li, Yuanyuan Hong, Suxing Li, Xi Li, Wenhui Tao, Yu S. Huang, Weizhi Chen, Chunguang Li
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Detection of cancer and identification of tumor origin at an early stage improve the survival and prognosis of patients. Herein, we proposed a plasma cfDNA-based approach called TOTEM to detect and trace the cancer signal origin (
Externí odkaz:
https://doaj.org/article/8d6589fa390641a9a252fde9aec24d33