Zobrazeno 1 - 10
of 1 832
pro vyhledávání: '"ceritinib"'
Publikováno v:
Journal of Cancer Research and Practice, Vol 11, Iss 2, Pp 77-80 (2024)
Inflammatory myofibroblastic tumor (IMT) is an intermediate malignant neoplasm, and approximately 50% of patients are anaplastic lymphoma kinase positive (ALK+). Given this unique trait, ALK tyrosine kinase inhibitors (TKIs), initially developed for
Externí odkaz:
https://doaj.org/article/745795b0085b4962a4cabca721e9aef9
Publikováno v:
Tehnički Glasnik, Vol 18, Iss 3, Pp 354-362 (2024)
The development of a quantitative in-line UV spectroscopic method for monitoring of solute concentration during the crystallization process of the active pharmaceutical ingredient (API), ceritinib is described. The method is based on artificial neura
Externí odkaz:
https://doaj.org/article/742cfd49451741d8ac61fcfa43a4d075
Publikováno v:
Crystals, Vol 14, Iss 11, p 975 (2024)
The formulation process for some drugs can be challenging, due to their unfavorable physical and mechanical properties and poor water solubility. Powder technology has made a significant impact in regard to the modification of the particles in active
Externí odkaz:
https://doaj.org/article/ac5a7a40feca437594bf945e8dc08fef
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Lung Cancer: Targets and Therapy, Vol Volume 14, Pp 57-62 (2023)
Alexandria TM Lee,1 Saihong Ignatius Ou1,2 1University of California Irvine School of Medicine, Department of Medicine, Orange, CA, USA; 2Chao Family Comprehensive Cancer Center, Orange, CA, USACorrespondence: Saihong Ignatius Ou, University of Calif
Externí odkaz:
https://doaj.org/article/a4920faea99648adaa4cc549408017c6
Drug interactions between ALK inhibitors and warfarin with concurrent use of bucolome: a case report
Autor:
Takashi Kato, Yusuke Kunimoto, Manabu Kitagawa, Yuichiro Asai, Tomoko Kimyo, Hiromasa Nakata, Mamoru Takahashi, Hirofumi Chiba, Hiroki Takahashi, Atsushi Miyamoto, Masahide Fukudo
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 9, Iss 1, Pp 1-6 (2023)
Abstract Background Alectinib, crizotinib, and ceritinib, are anaplastic lymphoma kinase-tyrosine kinase inhibitors (ALK-TKIs) that exhibit high protein binding, and their metabolism is associated with the cytochrome P450 (CYP) isoenzymes 2C9 or 3A4.
Externí odkaz:
https://doaj.org/article/d67de4a784ab4340b822547803d16150
Publikováno v:
Cancer Medicine, Vol 11, Iss 23, Pp 4491-4500 (2022)
Abstract Background Anaplastic lymphoma kinase (ALK) fusion is a prognostic indicator for patients with non‐small cell lung cancer (NSCLC) receiving tyrosine kinase inhibitors (TKIs). The real‐world data of ALK TKIs remain a major concern. Method
Externí odkaz:
https://doaj.org/article/c41c8d0da1ce4330976c2dfc38f0964d
Publikováno v:
AMB Express, Vol 12, Iss 1, Pp 1-15 (2022)
Key points Ceritinib showed fierce lethality to the planktonic and persistent S. aureus. Ceritinib were highly effective in MRSA biofilm eradication and inhibition. The bactericidal mechanisms of ceritinib were showed by membrane breaking and ROS act
Externí odkaz:
https://doaj.org/article/aa2ac703962c4307b8c03d2b52a3809c
Autor:
Kyaw Zwar Myint, Brinda Balasubramanian, Simran Venkatraman, Suchada Phimsen, Supisara Sripramote, Jeranan Jantra, Chaiwat Choeiphuk, Somkit Mingphruedhi, Paramin Muangkaew, Narongsak Rungsakulkij, Pongsatorn Tangtawee, Wikran Suragul, Watoo Vassanasiri Farquharson, Kanokpan Wongprasert, Somchai Chutipongtanate, Pimtip Sanvarinda, Marisa Ponpuak, Naravat Poungvarin, Tavan Janvilisri, Tuangporn Suthiphongchai, Kiren Yacqub-Usman, Anna M. Grabowska, David O. Bates, Rutaiwan Tohtong
Publikováno v:
Pharmaceuticals, Vol 17, Iss 2, p 197 (2024)
Cholangiocarcinoma (CCA) is a difficult-to-treat cancer, with limited therapeutic options and surgery being the only curative treatment. Standard chemotherapy involves gemcitabine-based therapies combined with cisplatin, oxaliplatin, capecitabine, or
Externí odkaz:
https://doaj.org/article/61c5f9c5650f4995b33765a79df28a4a
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.