Zobrazeno 1 - 10
of 17
pro vyhledávání: '"cerebrospinal fluid [Lewy Body Disease]"'
Autor:
Kathrin Brockmann, Corinne Quadalti, Stefanie Lerche, Marcello Rossi, Isabel Wurster, Simone Baiardi, Benjamin Roeben, Angela Mammana, Milan Zimmermann, Ann-Kathrin Hauser, Christian Deuschle, Claudia Schulte, Katharina Waniek, Ingolf Lachmann, Simon Sjödin, Ann Brinkmalm, Kaj Blennow, Henrik Zetterberg, Thomas Gasser, Piero Parchi
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications 9(1), 175 (2021). doi:10.1186/s40478-021-01276-6
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-11 (2021)
Acta Neuropathologica Communications 9(1), 175 (2021). doi:10.1186/s40478-021-01276-6
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-11 (2021)
The clinicopathological heterogeneity in Lewy-body diseases (LBD) highlights the need for pathology-driven biomarkers in-vivo. Misfolded alpha-synuclein (α-Syn) is a lead candidate based on its crucial role in disease pathophysiology. Real-time quak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2d1d53c06c19af096e6db752e03de26d
http://hdl.handle.net/11585/870280
http://hdl.handle.net/11585/870280
Autor:
Daniela Varges, Saima Zafar, Fabian Maass, Karin Gmitterová, Matthias Schmitz, Paul Lingor, Inga Zerr
Publikováno v:
Journal of Alzheimer's disease 73(4), 1355-1361 (2020). doi:10.3233/JAD-191153
BACKGROUND Chromogranin A (CgA) is a general marker of gut endocrine cells, which are part of the "gut-brain axis" in Parkinson's disease (PD). OBJECTIVE We analyzed CgA as a marker of synaptic dysfunction to assess its role in the differential diagn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab26c5d71ffd0606ded6ff38058c015
https://pub.dzne.de/record/151671
https://pub.dzne.de/record/151671
Publikováno v:
European archives of psychiatry and clinical neuroscience 270(4), 461-470 (2018). doi:10.1007/s00406-018-0928-9
Dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD) share a couple of clinical similarities that is often a source of diagnostic pitfalls. We evaluated the discriminatory potential of brain-derived CSF markers [tau, p-tau (181P),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c0358c3094e2ed72e6992c01e20cef0
https://doi.org/10.1007/s00406-018-0928-9
https://doi.org/10.1007/s00406-018-0928-9
Autor:
Maria Carmona-Iragui, Marc Suárez-Calvet, Christian Haass, Marta Querol-Vilaseca, Roser Ribosa-Nogué, Ignacio Illán-Gala, Estrella Morenas-Rodríguez, Rafael Blesa, Laia Muñoz-Llahuna, Juan Fortea, Alberto Lleó, Andrea Subirana, Eduard Vilaplana, Isabel Sala, Daniel Alcolea
Publikováno v:
Scientific Reports
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Scientific reports 9(1), 7803 (2019). doi:10.1038/s41598-019-44173-8
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Scientific reports 9(1), 7803 (2019). doi:10.1038/s41598-019-44173-8
The role of innate immunity in dementia with Lewy bodies (DLB) has been little studied. We investigated the levels in cerebrospinal fluid (CSF) of glial proteins YKL-40, soluble TREM2 (sTREM2) and progranulin in DLB and their relationship with Alzhei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f8ff7e48df62554319e98ddf82d2cb0
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2319
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2319
Autor:
Daniela Varges, Sara Friederike Gloeckner, Christian Schmidt, Peter Hermann, Franc Llorens, Matthias Schmitz, Lisa Kaerst, Inga Zerr
Publikováno v:
Journal of the neurological sciences 358(1-2), 398-403 (2015). doi:10.1016/j.jns.2015.10.011
Background Alterations in the CSF/serum albumin ratio (Qalb) is currently recognized as one of the most reliable markers of blood–brain barrier impairment and blood-CSF barrier permeability, but its potential role as a biomarker in the differential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5cf135e383406b8acf2bcc5cd62944
https://doi.org/10.1016/j.jns.2015.10.011
https://doi.org/10.1016/j.jns.2015.10.011
Autor:
Christian Deuschle, Stephan Theiss, Henner Koch, Walter Maetzler, Marcel Dihné, Holger Lerche
Publikováno v:
Neuroreport 28(16), 1061-1065 (2017). doi:10.1097/WNR.0000000000000890
One of the core clinical criteria of Dementia with Lewy bodies (DLB) are fluctuations of cognition. Underlying processes may be rather functional than neurodegenerative, reflected by, for example, factors present in cerebrospinal fluid (CSF). The aim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::107f1b4032178acf83966b772b8425d7
https://pub.dzne.de/record/139535
https://pub.dzne.de/record/139535
Autor:
Niels Kruse, Inga Zerr, Nadine Gotzmann, Franc Llorens, Daniela Varges, Karin Gmitterová, Matthias Schmitz, Brit Mollenhauer
Publikováno v:
Journal of neurology 263(11), 2271-2277 (2016). doi:10.1007/s00415-016-8259-0
Several studies have addressed the utility of cerebrospinal (CSF) α-synuclein levels as a potential biomarker of α-synuclein aggregation disorders. However, its relevance in the differential diagnostic context of neurodegenerative and movement diso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84544ad531d19edfbc0b6ff23ab3ea3c
https://pubmed.ncbi.nlm.nih.gov/27544498
https://pubmed.ncbi.nlm.nih.gov/27544498
Autor:
Walter Maetzler, Willy Deleersnijder, Valérie Hanssens, Alice Bernard, Kathrin Brockmann, Justus Marquetand, Isabel Wurster, Tim W Rattay, Lorenzo Roncoroni, Eva Schaeffer, Stefanie Lerche, Anja Apel, Christian Deuschle, Daniela Berg
Publikováno v:
PLoS ONE
PLOS ONE.-San Francisco : PloS one; 2016.-S.e0149349:1-e0149349:12.
PLOS ONE 11(3), e0149349 (2016). doi:10.1371/journal.pone.0149349
PLoS ONE, Vol 11, Iss 3, p e0149349 (2016)
PLOS ONE.-San Francisco : PloS one; 2016.-S.e0149349:1-e0149349:12.
PLOS ONE 11(3), e0149349 (2016). doi:10.1371/journal.pone.0149349
PLoS ONE, Vol 11, Iss 3, p e0149349 (2016)
Based on animal and ex-vivo experiments, Growth/Differentiation Factor-15 (GDF15, also called Macrophage Inhibitory Cytokine-1, MIC1), a member of the transforming growth factor-beta family, and Matrix Metalloproteinase-9 (MMP9), a member of the matr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::adadc07b26ec5a02a57a10d8dd84c957
http://europepmc.org/articles/PMC4777571
http://europepmc.org/articles/PMC4777571
Autor:
Anne Stuendl, Anja Schneider, Niels Kruse, Karin M Danzer, Claudia Bartels, Wiebke Moebius, Brit Mollenhauer, Marcel Kunadt
Publikováno v:
Brain 139(2), 481-494 (2016). doi:10.1093/brain/awv346
Brain
Brain
Stuendl et al. show that CSF exosomes of patients with Parkinson’s disease or dementia with Lewy bodies contain α-synuclein and induce α-synuclein aggregation in a reporter cell line. Thus, exosomes may support inter-neuronal transmission of α-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f883839ae4e15e0783f3cb449e91ae
https://pub.dzne.de/record/138377
https://pub.dzne.de/record/138377
Autor:
Markus Langkamp, Daniela Berg, Thomas Gasser, Jana Godau, Stephanie C. Hörnig, Kathrin Brockmann, Matthis Synofzik, Walter Maetzler, Arthur Melms
Publikováno v:
Journal of Alzheimer's disease 26(1), 171-179 (2011). doi:10.3233/JAD-2011-110221
There is increasing evidence that in Lewy body-associated dementias (encompassing Parkinson's disease with dementia (PDD) and dementia with Lewy bodies (DLB)), the adaptive immune system is altered and the degenerative process includes glial cells in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf0fbfc898e4c853a930d5061eb50e70
https://doi.org/10.3233/jad-2011-110221
https://doi.org/10.3233/jad-2011-110221