Zobrazeno 1 - 2
of 2
pro vyhledávání: '"cerebrospinal fluid [Intercellular Signaling Peptides and Proteins]"'
Autor:
Wilke, Carlo, Gillardon, Frank, Deuschle, Christian, Hobert, Markus A., Jansen, Iris E., Metzger, Florian G., Heutink, Peter, Gasser, Thomas, Maetzler, Walter, Blauwendraat, Cornelis, Synofzik, Matthis
Publikováno v:
Neurodegenerative Diseases, 17(2-3), 83-88. S. Karger AG
Neurodegenerative diseases 17(2-3), 83-88 (2016). doi:10.1159/000448896
Wilke, C, Gillardon, F, Deuschle, C, Hobert, M A, Jansen, I E, Metzger, F G, Heutink, P, Gasser, T, Maetzler, W, Blauwendraat, C & Synofzik, M 2017, ' Cerebrospinal Fluid Progranulin, but Not Serum Progranulin, Is Reduced in GRN-Negative Frontotemporal Dementia ', Neurodegenerative Diseases, vol. 17, no. 2-3, pp. 83-88 . https://doi.org/10.1159/000448896
Neurodegenerative diseases 17(2-3), 83-88 (2016). doi:10.1159/000448896
Wilke, C, Gillardon, F, Deuschle, C, Hobert, M A, Jansen, I E, Metzger, F G, Heutink, P, Gasser, T, Maetzler, W, Blauwendraat, C & Synofzik, M 2017, ' Cerebrospinal Fluid Progranulin, but Not Serum Progranulin, Is Reduced in GRN-Negative Frontotemporal Dementia ', Neurodegenerative Diseases, vol. 17, no. 2-3, pp. 83-88 . https://doi.org/10.1159/000448896
Background and Objective: Reduced progranulin levels are a hallmark of frontotemporal dementia (FTD) caused by loss-of-function (LoF) mutations in the progranulin gene (GRN). However, alterations of central nervous progranulin expression also occur i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ba7f66d06568870d5a3f42ccd82c39a8
https://research.vumc.nl/en/publications/9ed95381-38b5-4de0-b0c0-bcd7f109eb31
https://research.vumc.nl/en/publications/9ed95381-38b5-4de0-b0c0-bcd7f109eb31
Autor:
Carlo Wilke, Frank Gillardon, Christian Deuschle, Evelyn Dubois, Markus A. Hobert, Jennifer Müller vom Hagen, Stefanie Krüger, Saskia Biskup, Cornelis Blauwendraat, Michael Hruscha, Stephan A. Kaeser, Peter Heutink, Walter Maetzler, Matthis Synofzik
Publikováno v:
Current Alzheimer research 13(6), 654-662 (2016). doi:10.2174/1567205013666160314151247
Altered progranulin levels play a major role in neurodegenerative diseases, like Alzheimer's dementia (AD), frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), even in the absence of GRN mutations. Increasing progranulin levels cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::303968570e6dffeaceb83aa2bd94764d
https://pubmed.ncbi.nlm.nih.gov/26971930
https://pubmed.ncbi.nlm.nih.gov/26971930
