Zobrazeno 1 - 2
of 2
pro vyhledávání: '"cerebrospinal fluid [Huntington Disease]"'
Autor:
Peggy Barschke, Samir Abu-Rumeileh, M. H. D. Rami Al Shweiki, Lorenzo Barba, Federico Paolini Paoletti, Patrick Oeckl, Petra Steinacker, Steffen Halbgebauer, Lorenzo Gaetani, Jan Lewerenz, Albert Christian Ludolph, Georg Bernhard Landwehrmeyer, Lucilla Parnetti, Markus Otto
Publikováno v:
Journal of neurology 269(9), 5136-5143 (2022). doi:10.1007/s00415-022-11187-8
Background Proenkephalin (PENK) and prodynorphin (PDYN) are peptides mainly produced by the striatal medium spiny projection neurons (MSNs) under dopaminergic signaling. Therefore, they may represent candidate biomarkers in Huntington’s disease (HD
Autor:
Rebecca Schüle, Kina Höglund, Jens Kuhle, Christian Barro, Kaj Blennow, Fani Pujol-Calderón, Christian Deuschle, Matthis Synofzik, Elke Stransky, Zuzanna Michalak, Henrik Zetterberg, Andreas Jeromin, Carlo Wilke
Publikováno v:
Clinical chemistry and laboratory medicine 57(10), 1556-1564 (2019). doi:10.1515/cclm-2019-0015
Background Phosphorylated neurofilament heavy (pNfH), a neuronal cytoskeleton protein, might provide a promising blood biomarker of neuronal damage in neurodegenerative diseases (NDDs). The best analytical approaches to measure pNfH levels and whethe