Zobrazeno 1 - 4
of 4
pro vyhledávání: '"cerebrospinal fluid [Aspartic Acid Endopeptidases]"'
An optimized quantitative proteomics method establishes the cell type-resolved mouse brain secretome
Autor:
Johanna Tüshaus, Dmitrij Frishman, Minhui Su, Gökhan Güner, Stefan F. Lichtenthaler, Mikael Simons, Georg Jocher, Sabina Tahirovic, Jan Zaucha, Laura Sebastian Monasor, Stephan A. Müller, Evans Kataka
Publikováno v:
The EMBO journal 39(20), e105693 (2020). doi:10.15252/embj.2020105693
The EMBO Journal
The EMBO Journal
To understand how cells communicate in the nervous system, it is essential to define their secretome, which is challenging for primary cells because of large cell numbers being required. Here, we miniaturized secretome analysis by developing the “h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e431959c6cfdf27737f316819ef48ffc
https://pub.dzne.de/record/154360
https://pub.dzne.de/record/154360
Autor:
Alexopoulos, Panagiotis, Thierjung, Nathalie, Grimmer, Timo, Ortner, Marion, Economou, Polychronis, Assimakopoulos, Konstantinos, Gourzis, Philippos, Politis, Antonios, Perneczky, Robert, Initiative, The Alzheimer’s Disease Neuroimaging
Publikováno v:
Dementia and geriatric cognitive disorders 45(3-4), 152-161 (2018). doi:10.1159/000488481
Background/Aims: The utility of β-site amyloid-β precursor protein (AβPP) cleaving enzyme 1 (BACE1) activity and soluble AβPP β (sAβPPβ) levels in cerebrospinal fluid (CSF) in detecting Alzheimer’s disease (AD) is still elusive. Methods: BAC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd3cc65ea397403855052df8c426e88c
http://hdl.handle.net/10044/1/59716
http://hdl.handle.net/10044/1/59716
Autor:
Amalia Tsolakidou, Christian Sorg, Gjermund Henriksen, Robert Perneczky, Alexander Kurz, Panagiotis Alexopoulos, Timo Grimmer, Liang-Hao Guo, Behrooz H. Yousefi, Hans Förstl, Alexander Drzezga
Publikováno v:
The Scientific World Journal, Vol 2012 (2012)
The Scientific World Journal
The Scientific World Journal
The secretase BACE1 is fundamentally involved in the development of cerebral amyloid pathology in Alzheimer's disease (AD). It has not been studied so far to what extent BACE1 activity in cerebrospinal fluid (CSF) mirrors in vivo amyloid load in AD.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bce79fa75cf6b7938804cf7026de26a2
http://hdl.handle.net/10044/1/60380
http://hdl.handle.net/10044/1/60380
Autor:
Ping He, Cathal Walsh, Harald Hampel, Thomas Meindl, Hikmet Nural, Katharina Buerger, Zhenyu Zhong, Yong Shen, Xin Cheng, Michael Ewers, Stefan J. Teipel
Publikováno v:
Journal of Alzheimer's disease 25(2), 373-381 (2011). doi:10.3233/JAD-2011-091153
The enzyme β-secretase (BACE1) is essentially involved in the production of cerebral amyloidogenic pathology in Alzheimer's disease (AD). The measurement of BACE1 activity in cerebrospinal fluid (CSF) has been reported, which may render CSF measurem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::accaa31cdccadf1a9de3228fd161d0b9
https://pubmed.ncbi.nlm.nih.gov/21460439
https://pubmed.ncbi.nlm.nih.gov/21460439
