Zobrazeno 1 - 10
of 3 403
pro vyhledávání: '"cerebral ischemia-reperfusion injury"'
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-13 (2024)
Abstract Ischemic stroke (IS) is a severe cerebrovascular disease with high disability and mortality rates, where the inflammatory response is crucial to its progression and prognosis. Efferocytosis, the prompt removal of dead cells, can reduce exces
Externí odkaz:
https://doaj.org/article/769d6931c6be404c9c5c9f9dd43d1d1d
Autor:
Ma CS, Ma YP, Han B, Duan WL, Meng SC, Bai M, Dong H, Zhang LY, Duan MY, Liu J, Deng AJ, He MT
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 9175-9193 (2024)
Chang-Sheng Ma,1,2,* Ya-Ping Ma,1,3,* Bo Han,1,2,* Wan-Li Duan,1 Shu-Chen Meng,1 Min Bai,1 Hao Dong,1 Li-Ying Zhang,1 Meng-Yuan Duan,1,2 Jing Liu,1 Ai-Jun Deng,2 Mao-Tao He1,2 1Department of Basic Medical Sciences, Shandong Second Medical
Externí odkaz:
https://doaj.org/article/975d0280385a4f92b32020435134c93a
Autor:
Qi Liu, Jianye Xie, Runxue Zhou, Jin Deng, Weihong Nie, Shuwei Sun, Haiping Wang, Chunying Shi
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 2, Pp 503-517 (2025)
Vascular endothelial growth factor and its mimic peptide KLTWQELYQLKYKGI (QK) are widely used as the most potent angiogenic factors for the treatment of multiple ischemic diseases. However, conventional topical drug delivery often results in a burst
Externí odkaz:
https://doaj.org/article/b696d74a84de4640b5f070b531a23ce4
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 5741-5762 (2024)
Peijie Zhou,* Shangshang Yu,* Xuan Wang,* Xiaofei Zhang, Dongyan Guo, Chongbo Zhao, Jiangxue Cheng, Jing Wang, Jing Sun Department of Pharmaceutics, College of Pharmacy, The Key Laboratory of Basic and New Drug Research of Traditional Chi
Externí odkaz:
https://doaj.org/article/2876ded7d73146e6a7261f3ed160a24b
Autor:
Weijie Yang, Xiuxing Lei, Fengying Liu, Xin Sui, Yi Yang, Zhenyu Xiao, Ziqi cui, Yangyang Sun, Jun Yang, Xinyi Yang, Xueyang Lin, Zhenghao Bao, Weidong Li, Yingkai Ma, Yongan Wang, Yuan Luo
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Stroke is a globally dangerous disease capable of causing irreversible neuronal damage with limited therapeutic options. Meldonium, an inhibitor of carnitine-dependent metabolism, is considered an anti-ischemic drug. However, the
Externí odkaz:
https://doaj.org/article/3696dff9a8ac4c46b00bdc53c0012fb9
Autor:
Xiaobing Lan, Qing Wang, Yue Liu, Qing You, Wei Wei, Chunhao Zhu, Dongmei Hai, Zhenyu Cai, Jianqiang Yu, Jian Zhang, Ning Liu
Publikováno v:
Redox Biology, Vol 77, Iss , Pp 103406- (2024)
Cerebral ischemia-reperfusion injury (CIRI) refers to a secondary brain injury that occurs when blood supply is restored to ischemic brain tissue and is one of the leading causes of adult disability and mortality. Multiple pathological mechanisms are
Externí odkaz:
https://doaj.org/article/8a82f93d358f4334843dcfc85b474cf3
Publikováno v:
Immunity, Inflammation and Disease, Vol 12, Iss 10, Pp n/a-n/a (2024)
Abstract Background Cerebral ischemic disease is a common cerebrovascular disease, especially ischemic stroke. Exercise has protective functions on brain tissues following cerebral ischemia‐reperfusion injury (CIRI), but its preventive effects and
Externí odkaz:
https://doaj.org/article/91b2a1e3aa494cf79b6fd2f7f5224094
Publikováno v:
Brain Research Bulletin, Vol 216, Iss , Pp 111043- (2024)
Objective: This study aimed to further elucidate the mechanism of ginsenoside Rg1 in the treatment of cerebral ischemia-reperfusion. Methods: In this study, we observed the apoptosis of RM cells (microglia) after oxygen-glucose deprivation/reoxygenat
Externí odkaz:
https://doaj.org/article/735cc12c362d4f7ead0b4c85189d83d3
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Copper is an important mineral, and moderate copper is required to maintain physiological processes in nervous system including cerebral ischemia/reperfusion (I/R) injury. Over the past few decades, copper induced cell death, named cuprotosis, has at
Externí odkaz:
https://doaj.org/article/bd28bc4c0bb74a2186ecaf1970484654
Publikováno v:
Brain Research Bulletin, Vol 215, Iss , Pp 111025- (2024)
Objective: Research has shown that cerebral ischemia-reperfusion injury (CIRI) involves a series of physiological and pathological mechanisms, including inflammation, oxidative stress, and cell apoptosis. The cannabinoid receptor 2 agonist AM1241 has
Externí odkaz:
https://doaj.org/article/28088b5a362546b895b22c505ee65ebd