Zobrazeno 1 - 10
of 6 846
pro vyhledávání: '"cerebral ischemia reperfusion"'
Publikováno v:
Zhongguo cuzhong zazhi, Vol 19, Iss 11, Pp 1321-1332 (2024)
目的 探究肉苁蓉总苷通过激活PI3K-Akt信号通路对大鼠脑缺血再灌注损伤（cerebral ischemia-reperfusion injury，CIRI）的保护作用及机制。 方法 60只雄性Wistar大鼠随机分为假手术组、模型组、肉苁蓉
Externí odkaz:
https://doaj.org/article/332232472c094973acc7554f25889f85
Autor:
Jiahui Li, Xiaolei Liu, Zengze Wang, Pengyun Xie, Min Zhu, Hanhui Zhong, Sirui Luo, Jing Tang, Guixi Mo
Publikováno v:
Biological Research, Vol 57, Iss 1, Pp 1-14 (2024)
Abstract Background Stroke is a leading cause of death worldwide, with oxidative stress and calcium overload playing significant roles in the pathophysiology of the disease. Ozone, renowned for its potent antioxidant properties, is commonly employed
Externí odkaz:
https://doaj.org/article/1be8fa83c0804210be284b8aee7ddefa
Autor:
Lin-Yan Huang, Yi-De Zhang, Jie Chen, Hai-Di Fan, Wan Wang, Bin Wang, Ju-Yun Ma, Peng-Peng Li, Hai-Wei Pu, Xin-Yian Guo, Jian-Gang Shen, Su-Hua Qi
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 3, Pp 845-857 (2025)
It has been shown clinically that continuous removal of ischemia/reperfusion-induced reactive oxygen species is not conducive to the recovery of late stroke. Indeed, previous studies have shown that excessive increases in hypochlorous acid after stro
Externí odkaz:
https://doaj.org/article/08ee337d90284669a878ac0b5ed188cd
Autor:
Qi Liu, Jianye Xie, Runxue Zhou, Jin Deng, Weihong Nie, Shuwei Sun, Haiping Wang, Chunying Shi
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 2, Pp 503-517 (2025)
Vascular endothelial growth factor and its mimic peptide KLTWQELYQLKYKGI (QK) are widely used as the most potent angiogenic factors for the treatment of multiple ischemic diseases. However, conventional topical drug delivery often results in a burst
Externí odkaz:
https://doaj.org/article/b696d74a84de4640b5f070b531a23ce4
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-13 (2024)
Abstract Ischemic stroke (IS) is a severe cerebrovascular disease with high disability and mortality rates, where the inflammatory response is crucial to its progression and prognosis. Efferocytosis, the prompt removal of dead cells, can reduce exces
Externí odkaz:
https://doaj.org/article/769d6931c6be404c9c5c9f9dd43d1d1d
Autor:
Ma CS, Ma YP, Han B, Duan WL, Meng SC, Bai M, Dong H, Zhang LY, Duan MY, Liu J, Deng AJ, He MT
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 9175-9193 (2024)
Chang-Sheng Ma,1,2,* Ya-Ping Ma,1,3,* Bo Han,1,2,* Wan-Li Duan,1 Shu-Chen Meng,1 Min Bai,1 Hao Dong,1 Li-Ying Zhang,1 Meng-Yuan Duan,1,2 Jing Liu,1 Ai-Jun Deng,2 Mao-Tao He1,2 1Department of Basic Medical Sciences, Shandong Second Medical
Externí odkaz:
https://doaj.org/article/975d0280385a4f92b32020435134c93a
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 5741-5762 (2024)
Peijie Zhou,* Shangshang Yu,* Xuan Wang,* Xiaofei Zhang, Dongyan Guo, Chongbo Zhao, Jiangxue Cheng, Jing Wang, Jing Sun Department of Pharmaceutics, College of Pharmacy, The Key Laboratory of Basic and New Drug Research of Traditional Chi
Externí odkaz:
https://doaj.org/article/2876ded7d73146e6a7261f3ed160a24b
Autor:
Weijie Yang, Xiuxing Lei, Fengying Liu, Xin Sui, Yi Yang, Zhenyu Xiao, Ziqi cui, Yangyang Sun, Jun Yang, Xinyi Yang, Xueyang Lin, Zhenghao Bao, Weidong Li, Yingkai Ma, Yongan Wang, Yuan Luo
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Stroke is a globally dangerous disease capable of causing irreversible neuronal damage with limited therapeutic options. Meldonium, an inhibitor of carnitine-dependent metabolism, is considered an anti-ischemic drug. However, the
Externí odkaz:
https://doaj.org/article/3696dff9a8ac4c46b00bdc53c0012fb9
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Salidroside is the major bioactive and pharmacological active substance in Rhodiola rosea L. It has been reported to have neuroprotective effects on cerebral ischemia/reperfusion (I/R). However, whether salidroside can enhance neu
Externí odkaz:
https://doaj.org/article/7c033ee4e5ed40dca5ea6ddb3f5d28c4
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-18 (2024)
Abstract Background Investigating immune cell infiltration in the brain post-ischemia-reperfusion (I/R) injury is crucial for understanding and managing the resultant inflammatory responses. This study aims to unravel the role of the RPS27A-mediated
Externí odkaz:
https://doaj.org/article/615060b9ff634c2a9ccef33f7ab68b35