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IMiD/CELMoD-induced growth suppression of adult T-cell leukemia/lymphoma cells via cereblon through downregulation of target proteins and their downstream effectors.

Autor: Wang Y; Department of Microbiology, Faculty of Medicine, Oita University, Yufu, Japan., Shimosaki S; Division of Tumor and Cellular Biochemistry, Department of Medical Sciences, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan., Ikebe E; Department of Microbiology, Faculty of Medicine, Oita University, Yufu, Japan.; Research Center for Biological Products in the Next Generation, National Institute of Infectious Diseases, Musashi-murayama, Japan., Iha H; Department of Microbiology, Faculty of Medicine, Oita University, Yufu, Japan.; Division of Pathophysiology, The Research Center for GLOBAL and LOCAL Infectious Diseases (RCGLID), Oita University, Yufu, Japan.; Borneo Medical and Health Research Centre, Faculty of Medicine and Health Sciences, University of Malaysia Sabah, Kota Kinabalu, Malaysia., Yamamoto JI; Department of Nanoparticle Translational Research, Tokyo Medical University, Tokyo, Japan., Fife N; Department of Microbiology, Faculty of Medicine, Oita University, Yufu, Japan., Ichikawa T; Division of Tumor and Cellular Biochemistry, Department of Medical Sciences, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan., Hori M; Department of Hematology, Ibaraki Prefectural Central Hospital, Kasama, Japan., Ogata M; Division of Pathophysiology, The Research Center for GLOBAL and LOCAL Infectious Diseases (RCGLID), Oita University, Yufu, Japan.; Department of Hematology and Oncology, Faculty of Medicine, Oita University, Yufu, Japan., Tsukamoto Y; Department of Molecular Pathology, Faculty of Medicine, Oita University, Yufu, Japan., Hijiya N; Department of Molecular Pathology, Faculty of Medicine, Oita University, Yufu, Japan., Moriyama M; Department of Molecular Pathology, Faculty of Medicine, Oita University, Yufu, Japan., Hagiwara S; Mito Center for Regional Medical Education, University of Tsukuba, Ibaraki, Japan., Kusano S; Division of Biological Information Technology, Joint Research Center for Human Retrovirus Infection, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan., Saito M; Research Center for Biological Products in the Next Generation, National Institute of Infectious Diseases, Musashi-murayama, Japan., Ahmed K; Borneo Medical and Health Research Centre, Faculty of Medicine and Health Sciences, University of Malaysia Sabah, Kota Kinabalu, Malaysia., Nishizono A; Department of Microbiology, Faculty of Medicine, Oita University, Yufu, Japan.; Division of Pathophysiology, The Research Center for GLOBAL and LOCAL Infectious Diseases (RCGLID), Oita University, Yufu, Japan., Handa H; Department of Nanoparticle Translational Research, Tokyo Medical University, Tokyo, Japan., Morishita K; Division of Tumor and Cellular Biochemistry, Department of Medical Sciences, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.

Publikováno v: Frontiers in oncology [Front Oncol] 2024 Jan 24; Vol. 13, pp. 1272528. Date of Electronic Publication: 2024 Jan 24 (Print Publication: 2023).