Zobrazeno 1 - 10
of 892
pro vyhledávání: '"cerebellar development"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
In the early cerebellar primordium, there are two progenitor zones, the ventricular zone (VZ) residing atop the IVth ventricle and the rhombic lip (RL) at the lateral edges of the developing cerebellum. These zones give rise to the several cell types
Externí odkaz:
https://doaj.org/article/52539f317ad54371922c8965a6f165ab
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Over the past decade, survival rates for extremely low gestational age neonates (ELGANs;
Externí odkaz:
https://doaj.org/article/05499f46b541495e9d7b2072d81ac7c9
Akademický článek
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Autor:
Ines Serra, Ana Stravs, Catarina Osório, Maria Roa Oyaga, Martijn Schonewille, Christian Tudorache, Aleksandra Badura
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Tuberous sclerosis complex 1 (TSC1) is a tumor suppressor that promotes the inhibition of mechanistic target of rapamycin (mTOR) pathway, and mutations in TSC1 lead to a rare complex disorder of the same name. Despite phenotype heterogeneity, up to 5
Externí odkaz:
https://doaj.org/article/a30af7024210428f9974adf262a2512e
Autor:
Fengjiao Liu, Shen Li, Xin Zhao, Saisai Xue, Hao Li, Guochao Yang, Ying Li, Yan Wu, Lingling Zhu, Liping Chen, Haitao Wu
Publikováno v:
Antioxidants, Vol 12, Iss 4, p 806 (2023)
Purkinje cells (PCs), as a unique type of neurons output from the cerebellar cortex, are essential for the development and physiological function of the cerebellum. However, the intricate mechanisms underlying the maintenance of Purkinje cells are un
Externí odkaz:
https://doaj.org/article/c273fc613f114d63bc4e49d937e8c530
Akademický článek
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Autor:
Richard Hawkes
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
The cerebellar cortex is highly compartmentalized and serves as a remarkable model for pattern formation throughout the brain. In brief, the adult cerebellar cortex is subdivided into five anteroposterior units—transverse zones—and subsequently,
Externí odkaz:
https://doaj.org/article/328e94457c3347e3b0cdb76b4f4b745e
Autor:
Thomas J. Ha, Peter G. Y. Zhang, Remi Robert, Joanna Yeung, Douglas J. Swanson, Anthony Mathelier, Wyeth W. Wasserman, Sujin Im, Masayoshi Itoh, Hideya Kawaji, Timo Lassmann, Carsten O. Daub, Erik Arner, The FANTOM Consortium, Piero Carninci, Yoshihide Hayashizaki, Alistair R. R. Forrest, Daniel Goldowitz
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-17 (2019)
Abstract Background The work of the FANTOM5 Consortium has brought forth a new level of understanding of the regulation of gene transcription and the cellular processes involved in creating diversity of cell types. In this study, we extended the anal
Externí odkaz:
https://doaj.org/article/26886484d3af4071954fe82631526e36
Publikováno v:
Cells, Vol 11, Iss 19, p 3013 (2022)
The cerebellar reserve is defined as the capacity of the cerebellum for compensation and restoration following injury. This unique cerebellar ability is attributed to various forms of synaptic plasticity that incorporate multimodal and redundant cere
Externí odkaz:
https://doaj.org/article/e1a21d9d51374127acb68f4f28157bc0
Autor:
Elijah D Lowenstein, Aleksandra Rusanova, Jonas Stelzer, Marc Hernaiz-Llorens, Adrian E Schroer, Ekaterina Epifanova, Francesca Bladt, Eser Göksu Isik, Sven Buchert, Shiqi Jia, Victor Tarabykin, Luis R Hernandez-Miranda
Publikováno v:
eLife, Vol 10 (2021)
The mature cerebellum controls motor skill precision and participates in other sophisticated brain functions that include learning, cognition, and speech. Different types of GABAergic and glutamatergic cerebellar neurons originate in temporal order f
Externí odkaz:
https://doaj.org/article/24f3885ee81b435fa971001cfc7200d9