Zobrazeno 1 - 10
of 36
pro vyhledávání: '"ceramide synthase 5"'
Akademický článek
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Akademický článek
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Autor:
Wei Zhang, Yubao Lu, Ruoqi Shen, Yingjie Wu, Chenrui Liu, Xingxing Fang, Liangming Zhang, Bin Liu, Limin Rong
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 10, Pp 2955-2968 (2025)
Microglia, the resident monocyte of the central nervous system, play a crucial role in the response to spinal cord injury. However, the precise mechanism remains unclear. To investigate the molecular mechanisms by which microglia regulate the neuroin
Externí odkaz:
https://doaj.org/article/23586777397b430bbd18620401c398bf
Autor:
Anthony S. Don, Shubiao Zhang, Xin Tracy Liu, Yang Zhao, Chanlu Xie, Felcia Lai, Long Hoa Chung, Yanfei Qi, I Gusti Md Gde Surya C Trapika, Jinbiao Chen, Collin Tran, George Q. Li, Qian Wang, Shaohui Cui, Jane R. Hanrahan
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology
Frontiers in Oncology
Prostate cancer is the second most prevalent malignancy worldwide. In the early stages, the development of prostate cancer is dependent on androgens. Over time with androgen deprivation therapy, 20% of prostate cancers progress to a castration-resist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d185725ddb8d405cad9cfa2e2d5c6a58
https://www.frontiersin.org/articles/10.3389/fonc.2021.738078/full
https://www.frontiersin.org/articles/10.3389/fonc.2021.738078/full
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Autor:
Debora Collotta, Massimo Collino, Katrien H.J. Gaens, Raffaella Mastrocola, Kristiaan Wouters, Claudio Medana, Alessia Sofia Cento, Federica Dal Bello, Casper G. Schalkwijk, Manuela Aragno
Publikováno v:
Free Radical Biology and Medicine, 169, 425-435. Elsevier Science
High plasma levels of the sphingolipid intermediates ceramide (Cer) and sphingosine-1-phosphate (S1P) are suggested to be involved in the development of insulin resistance (IR). Recent evidence indicates that advanced glycation endproducts (AGEs) can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85e87d9efce8ae908986be86381dfd7d
http://hdl.handle.net/2318/1789498
http://hdl.handle.net/2318/1789498
Autor:
Khadija El-Hindi, Kerstin Birod, Sabine Grösch, Jennifer Christina Hartel, Stephanie Oertel, Sebastian Brachtendorf, Andreas Weigert, Dominique Thomas, Thomas Ulshöfer, Martin Krönke, Olaf Utermöhlen, Sandra Trautmann
Publikováno v:
Cancers
Volume 12
Issue 7
Cancers, Vol 12, Iss 1753, p 1753 (2020)
Volume 12
Issue 7
Cancers, Vol 12, Iss 1753, p 1753 (2020)
Ceramide synthase 5 is one of six enzymes that catalyze the production of ceramides from sphingosine or sphinganine. Ceramides are important components of cell membranes and act as signaling molecules. Previously it has been shown that ceramide synth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5178df8a461e1c524032fb3f9933c55
http://europepmc.org/articles/PMC7409364
http://europepmc.org/articles/PMC7409364
Autor:
Sabine Grösch, Kerstin Birod, Dominique Thomas, Marthe-Susanna Wegner, Sandra Trautmann, Bernhard Brüne, Sebastian Brachtendorf, Ruth Anna Wanger, Gerd Geisslinger, Dominik C. Fuhrmann
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1863:1214-1227
Resistance against chemotherapy is a life-threatening complication in colon cancer therapy. To increase response rate, new additional targets that contribute to chemoresistance are still needed to be explored. Ceramides, which belong to the group of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40da9e16b2e2331aecbf709583100e02
https://doi.org/10.1016/j.bbalip.2018.07.011
https://doi.org/10.1016/j.bbalip.2018.07.011
Autor:
Mariana Nikolova-Karakashian, Zhihui Zhu, Erhard Bieberich, Xue Jiang, Liansheng Zhong, Ahmed Elsherbini, Hsuan-Pei Lin, Silvia Leanhart, Stefka D. Spassieva, Michael B. Dinkins, Ji Na Kong, Guanghu Wang, Rebecca Wang, Haiyan Qin
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 5, Pp 795-804 (2018)
Sphingolipids are key signaling lipids in cancer. Genome-wide studies have identified neutral SMase-2 (nSMase2), an enzyme generating ceramide from SM, as a potential repressor for hepatocellular carcinoma. However, little is known about the sphingol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4052e449bd2445e01af45cdf6a110fd5
https://doi.org/10.1194/jlr.m080879
https://doi.org/10.1194/jlr.m080879
Autor:
Daniel Houle, Danuta Radzioch, Juan B. De Sanctis, Shanon Cupri, John W. Hanrahan, Elias Matouk, Dušan Garić, Gabriella Wojewodka, Marian Hajduch, Asmahan Abu-Arish
Publikováno v:
Journal of Molecular Medicine. 95:1053-1064
Cystic fibrosis is the most common genetic disease, in which symptoms may be alleviated but not fully eliminated. Ceramides have long been implicated in the inflammatory etiology of cystic fibrosis, with contradicting reports with regards to their ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeec33d3b0a8f4c1c3cb7fa94115aaf5
https://doi.org/10.1007/s00109-017-1564-y
https://doi.org/10.1007/s00109-017-1564-y