Zobrazeno 1 - 10
of 9 177
pro vyhledávání: '"central sensitization"'
Autor:
Caterina Maria Leone, Andrea Truini
Publikováno v:
Journal of Anesthesia, Analgesia and Critical Care, Vol 4, Iss 1, Pp 1-9 (2024)
Abstract Neuropathic pain, arising from lesions of the somatosensory nervous system, presents with diverse symptoms including ongoing pain, paroxysmal pain, and provoked pain, usually accompanied by sensory deficits. Understanding the pathophysiologi
Externí odkaz:
https://doaj.org/article/57fa6a00dfca4a64b356feadf38ddd92
Autor:
Daisuke Danno, Noboru Imai, Shigekazu Kitamura, Kumiko Ishizaki, Shoji Kikui, Takao Takeshima
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Galcanezumab, a monoclonal antibody targeting the calcitonin gene-related peptide pathway (CGRP mAb), acts peripherally due to its large size. However, recent studies have suggested that CGRP mAbs may also have a central mode of action. This
Externí odkaz:
https://doaj.org/article/d0bb4eb582c842919f9ca919cd04f52e
Publikováno v:
Journal of Joint Surgery and Research, Vol 2, Iss 4, Pp 168-172 (2024)
Purpose: Exacerbations of osteoarthritis (OA) pain significantly impair activities of daily living and walking, thereby reducing quality of life. Despite various treatments, persistent pain remains a challenge, particularly in patients with hip OA, w
Externí odkaz:
https://doaj.org/article/70e00bc28e164687b936ea801c854cd2
Publikováno v:
Brain Stimulation, Vol 17, Iss 4, Pp 911-924 (2024)
Background: The insula and dorsal anterior cingulate cortex (dACC) are core brain regions involved in pain processing and central sensitization, a shared mechanism across various chronic pain conditions. Methods to modulate these regions may serve to
Externí odkaz:
https://doaj.org/article/2fb6e0ed95c748b587bfb5e9fd854a74
Autor:
Julia Jessen, Oliver Höffken, Peter Schwenkreis, Martin Tegenthoff, Özüm Simal Özgül, Elena Enax-Krumova
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Posttraumatic headache (PTH) is common following traumatic brain injury and impacts quality of life. We investigated descending pain modulation as one possible mechanism for PTH and correlated it to clinical measures. Pain-related evoked pot
Externí odkaz:
https://doaj.org/article/87bfa6a9dd0743df96b5ce3d33a94b69
Publikováno v:
Annals of Indian Academy of Neurology, Vol 27, Iss 3, Pp 282-288 (2024)
Objectives: To investigate the presence and severity of central sensitization (CS) and its associations with clinical measures and quality of life (QoL) in individuals with a history of paralytic poliomyelitis with and without post-polio syndrome (PP
Externí odkaz:
https://doaj.org/article/40b0243e9dff4d29835e5c96ffb17b03
Autor:
Shahla Chaichian, Abolfazl Mehdizadehkashi, Ameneh Haghgoo, Marziyeh Ajdary, Roya Derakhshan, Samaneh Rokhgireh, Saeedeh Sarhadi, Banafsheh Nikfar
Publikováno v:
BMC Women's Health, Vol 24, Iss 1, Pp 1-7 (2024)
Abstract Background Endometriosis affects 10–15% of women of reproductive age and is considered a critical gynecological problem. Endometriosis causes pain and infertility, both of which can impair the patient’s quality of life. Sleep disorders a
Externí odkaz:
https://doaj.org/article/d25690516c66491582d79908f9ad213f
Publikováno v:
PeerJ, Vol 12, p e18251 (2024)
Background The Central Sensitization Inventory (CSI) is a patient-reported screening instrument that can be used to identify and assess central sensitization (CS)/Central Sensitization Syndrome (CSS)-related symptoms. Objective The aim was to transla
Externí odkaz:
https://doaj.org/article/6f0958453f8b4b91872d36fbc9ac95bd
Autor:
Anastasia A. Bialik, Andrey E. Karateev, Maxim A. Makarov, Vadim A. Nesterenko, Valerii E. Bialik
Publikováno v:
Научно-практическая ревматология, Vol 62, Iss 4 (2024)
The aim of the study – to identify the factors associated with the development of chronic post-traumatic pain (CPTP) in patients with knee joint (KJ) injury.Materials and methods. The study group consisted of 136 patients (51.5% women, age 38.7±12
Externí odkaz:
https://doaj.org/article/3323aa3794584ae1bf9bfc75f4f00b42
Autor:
Mario García-Domínguez
Publikováno v:
Frontiers in Aging, Vol 5 (2024)
Chronic pain is a debilitating condition frequently observed in the elderly, involving numerous pathological mechanisms within the nervous system. Diminished local blood flow, nerve degeneration, variations in fiber composition, alterations in ion ch
Externí odkaz:
https://doaj.org/article/9deb63e170e643fcafb2597ebd062136