Dérégulations épigénétiques suivant une perte temporaire de l'enzyme DNMT1

Autor: Lemieux, Anthony

Au cours du développement précoce de l'embryon, une importante vague de reprogrammation épigénétique efface et rétablit les profils de méthylation d’ADN (metADN) à travers le génome. Cependant, des régions spécifiques telles que les gèn

Externí odkaz: http://hdl.handle.net/1866/27146
https://orcid.org/0000-0002-0194-608X

Allele-specific RNA-seq expression profiling of imprinted genes in mouse isogenic pluripotent states

Autor: Andras Dinnyes, René A.M. Dirks, Alice Jouneau, Hindrik H. D. Kerstens, Julien Maruotti, Roger A. Pedersen, István Bock, Hendrik Marks, Martijn A. Huynen, Guido van Mierlo, Andreia S. Bernardo, Julianna Kobolák

Publikováno v: Epigenetics and Chromatin
Epigenetics and Chromatin, BioMed Central, 2019, 12 (1), pp.1-21. ⟨10.1186/s13072-019-0259-8⟩
Epigenetics & Chromatin
Epigenetics and Chromatin 1 (12), 1-21. (2019)
Epigenetics & Chromatin, 12, pp. 1-21
Epigenetics and Chromatin, 12(1)
Epigenetics and Chromatin 12 (2019) 1
Epigenetics & Chromatin, Vol 12, Iss 1, Pp 1-21 (2019)
Epigenetics and Chromatin, 2019, 12 (1), pp.1-21. ⟨10.1186/s13072-019-0259-8⟩
Epigenetics & Chromatin, 12, 1-21

Background Genomic imprinting, resulting in parent-of-origin specific gene expression, plays a critical role in mammalian development. Here, we apply allele-specific RNA-seq on isogenic B6D2F1 mice to assay imprinted genes in tissues from early embry

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6953769f564d0de22461f32cd5ece1
https://zenodo.org/record/2567638

NANOG Is Required for the Long-Term Establishment of Avian Somatic Reprogrammed Cells

Autor: Sylvie Rival-Gervier, Bertrand Pain, Clémence Kress, Pauline Aubel, Guillaume Montillet, Aurélie Fuet, Christian Jean

Publikováno v: Current Stem Cell Reports
Current Stem Cell Reports, Springer, 2018, 11 (5), pp.1272-1286. ⟨10.1016/j.stemcr.2018.09.005⟩
Stem Cell Reports, Vol 11, Iss 5, Pp 1272-1286 (2018)
Stem Cell Reports 5 (11), 1272-1286. (2018)
Stem Cell Reports

Summary Somatic reprogramming, which was first identified in rodents, remains poorly described in non-mammalian species. Here, we generated avian reprogrammed cells by reprogramming of chicken and duck primary embryonic fibroblasts. The efficient gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a8ae40d90d2cc355d7e491b7a56ce82
https://hal.archives-ouvertes.fr/hal-02517395

Mammalian embryo comparison identifies novel pluripotency genes associated with the naïve or primed state

Autor: Gregory Parsonage, Martijn A. Huynen, Anita Fehér, Giovanna Lazzari, István Bock, Andreia S. Bernardo, Hendrik Marks, Hendrik G. Stunnenberg, Philip R. Kensche, Zsuzsanna Polgar, Camille Bouissou, Kaveh Mashayekhi, James C. Smith, Roger A. Pedersen, Chiara Sartori, Hindrik H. D. Kerstens, Alice Jouneau, Julianna Kobolak, Vanessa Jane Hall, Kristine K. Freude, Poul Hyttel, Tiago Faial, Claire Louet, Andras Dinnyes

Publikováno v: Biology Open
Biology Open, Royal Society, 2018, ⟨10.1242/bio.033282⟩
Biology Open, 7, 1-17
Biology Open, Vol 7, Iss 8 (2018)
Bernardo, A S, Jouneau, A, Marks, H, Kensche, P, Kobolak, J, Freude, K, Hall, V, Feher, A, Polgar, Z, Sartori, C, Bock, I, Louet, C, Faial, T, Kerstens, H H D, Bouissou, C, Parsonage, G, Mashayekhi, K, Smith, J C, Lazzari, G, Hyttel, P, Stunnenberg, H G, Huynen, M, Pedersen, R A & Dinnyes, A 2018, ' Mammalian embryo comparison identifies novel pluripotency genes associated with the naive or primed state ', Biology Open, vol. 7, no. 8, bio033282 . https://doi.org/10.1242/bio.033282
Biology Open, . (2018)
Biology open, vol. 7, no. 8, pp. 1
Biology Open, 7, 8, pp. 1-17

During early mammalian development, transient pools of pluripotent cells emerge that can be immortalised upon stem cell derivation. The pluripotent state, ‘naïve’ or ‘primed’, depends on the embryonic stage and derivation conditions used. He

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e85fa4df31d6445d87d4d23ba1eec5
https://hal.inrae.fr/hal-02623684

Transcriptome analysis of chicken ES, blastodermal and germ cells reveals that chick ES cells are equivalent to mouse ES cells rather than EpiSC

Autor: Jean, Christian, Oliveira, Nidia M.M., Intarapat, Sittipon, Fuet, Aurélie, Mazoyer, Clément, De Almeida, Irene, Trevers, Katherine, Boast, Sharon, Aubel, Pauline, Bertocchini, Federica, Stern, Claudio, Pain, Bertrand

Publikováno v: Stem Cell Research, Vol 14, Iss 1, Pp 54-67 (2015)
Stem Cell Research
Stem Cell Research, Elsevier, 2015, 14 (1), pp.54-67. ⟨10.1016/j.scr.2014.11.005⟩
Stem cell research
Stem cell research, Elsevier, 2015, 14 (1), pp.54-67. ⟨10.1016/j.scr.2014.11.005⟩
Stem Cell Research, 2015, 14 (1), pp.54-67. ⟨10.1016/j.scr.2014.11.005⟩
Stem Cell Research 1 (14), 54-67. (2015)

Pluripotent Embryonic Stem cell (ESC) lines can be derived from a variety of sources. Mouse lines derived from the early blastocyst and from primordial germ cells (PGCs) can contribute to all somatic lineages and to the germ line, whereas cells from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::09c8a16c53946720916b7f7dfc789a2b