Zobrazeno 1 - 10
of 20
pro vyhledávání: '"cellular radiation Response"'
Autor:
Christine E. Hellweg, Luis F. Spitta, Kristina Koch, Arif A. Chishti, Bernd Henschenmacher, Sebastian Diegeler, Bikash Konda, Sebastian Feles, Claudia Schmitz, Thomas Berger, Christa Baumstark-Khan
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 8, p 2220 (2018)
Astronauts are exposed to considerable doses of space radiation during long-term space missions. As complete shielding of the highly energetic particles is impracticable, the cellular response to space-relevant radiation qualities has to be understoo
Externí odkaz:
https://doaj.org/article/184b6552ce794beab9447bb3a5dca54a
Autor:
Hellweg, Christine E., Spitta, Luis, Koch, Kristina, Chishti, Arif Ali, Henschenmacher, Bernd, Diegeler, Sebastian, Konda, Bikash, Feles, Sebastian, Schmitz, Claudia, Berger, Thomas, Baumstark-Khan, Christa
Publikováno v:
International Journal of Molecular Sciences
Volume 19
Issue 8
International Journal of Molecular Sciences, Vol 19, Iss 8, p 2220 (2018)
Volume 19
Issue 8
International Journal of Molecular Sciences, Vol 19, Iss 8, p 2220 (2018)
Astronauts are exposed to considerable doses of space radiation during long-term space missions. As complete shielding of the highly energetic particles is impracticable, the cellular response to space-relevant radiation qualities has to be understoo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::cc6791eaeefe2d31f21d120262f20b3c
Publikováno v:
The FASEB Journal. 32
The overall response to tumor radiation therapy results from direct radiation damage and indirect bystander effects (RIBE) mediated by secreted molecules and paracrine transfer of short-lived mediators. RIBE can have both detrimental and protective a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c10035f64abe1876fce20e9e1afc3f49
https://doi.org/10.1096/fasebj.2018.32.1_supplement.533.6
https://doi.org/10.1096/fasebj.2018.32.1_supplement.533.6
Publikováno v:
Cancers
Cancers, Vol 10, Iss 3, p 78 (2018)
Cancers, Vol 10, Iss 3, p 78 (2018)
Genetic alterations driving aberrant activation of the survival kinase Protein Kinase B (Akt) are observed with high frequency during malignant transformation and cancer progression. Oncogenic gene mutations coding for the upstream regulators or Akt,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::650091938df91dd6f75d00e80c483f3a
http://europepmc.org/articles/PMC5876653
http://europepmc.org/articles/PMC5876653
Protective signaling pathways in the cellular radiation response: Nuclear Factor κB (NF-κB) and Nrf2
Autor:
Henschenmacher, B., Crellin, A. J., Enyong, E., Chishti, A. A., Diegeler, S., Spitta, L. F., Koch, K., Konda, B., Feles, S., Schmitz, C., Baumstark, C., Hellweg, Christine E.
As a prerequisite for developing appropriate countermeasures to mitigate acute effects and late risks of ionizing radiation exposure, the role of protective pathways in the cellular radiation response needs to be better understood. The Nuclear Factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1640::ba2f79a785cf5567d147f8fd9195fd55
https://elib.dlr.de/112412/
https://elib.dlr.de/112412/
Autor:
Chishti, A.A., Koch, K., Spitta, L.F., Henschenmacher, B., Diegeler, S., Konda, B., Baumstark-Khan, C., Feles, S., Schmitz, C., Hellweg, C.E.
Introduction: As a prerequisite for developing appropriate countermeasures to mitigate acute effects and late radiation risks for the astronaut and thereby enabling long-term human space flight, the cellular radiation response to densely ionizing rad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1640::72db842c16b09e5f89d213d466bbc33e
https://elib.dlr.de/106182/
https://elib.dlr.de/106182/
Autor:
Christine E. Hellweg
Exposure to ionizing radiation modulates immune responses in a complex dose-dependent pattern, with possible anti-inflammatory effects in the low dose range, expression of pro-inflammatory cytokines at moderate doses and immunosuppression after expos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0dc2c4cf2dee5aa9506dae0fe505bde
https://elib.dlr.de/95586/
https://elib.dlr.de/95586/
Autor:
Koch, Kristina
Radiation is currently one of the most important limiting factors for manned space flight. During such missions, there is a constant exposure to low doses of galactic cosmic radiation and in particular high-energy heavy ions. Together this is associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f196369774cc24c433f0009b200ec5c9
https://kups.ub.uni-koeln.de/5128/
https://kups.ub.uni-koeln.de/5128/
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