Zobrazeno 1 - 10
of 1 149
pro vyhledávání: '"cellular mechanism"'
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-37 (2024)
Abstract PD-1/PD-L1 blockade therapies have displayed extraordinary clinical efficacy for melanoma, renal, bladder and lung cancer; however, only a minority of colorectal cancer (CRC) patients benefit from these treatments. The efficacy of PD-1/PD-L1
Externí odkaz:
https://doaj.org/article/75b7d016520743e0bde80f8c51b15e62
Publikováno v:
Guoji Yanke Zazhi, Vol 24, Iss 8, Pp 1266-1269 (2024)
Diabetic retinopathy(DR)is one of the most common retinal complications of diabetes could cause irreversible loss of central vision in the working-age population. Current studies showed that systemic risk factors, inflammatory response, and oxidative
Externí odkaz:
https://doaj.org/article/055f131d22684e03887ef211c8f7a435
Autor:
Qiaoyan Chen
Publikováno v:
Experimental Gerontology, Vol 196, Iss , Pp 112550- (2024)
Aging is an unavoidable process marked by numerous physiological and psychological changes that profoundly impact overall health and quality of life. As the global population ages, there is a growing interest in non-pharmacological therapies that can
Externí odkaz:
https://doaj.org/article/e01bd8bc45cf4c56ba444bee8dffe3ee
Autor:
Weronika Kruczkowska, Karol Kamil Kłosiński, Katarzyna Helena Grabowska, Julia Gałęziewska, Piotr Gromek, Mateusz Kciuk, Żaneta Kałuzińska-Kołat, Damian Kołat, Radosław A. Wach
Publikováno v:
Molecules, Vol 29, Iss 18, p 4360 (2024)
Carboxymethyl chitosan (CMCS) hydrogels have been investigated in biomedical research because of their versatile properties that make them suitable for various medical applications. Key properties that are especially valuable for biomedical use inclu
Externí odkaz:
https://doaj.org/article/1da1fd302516458894843ac382b0aacc
Publikováno v:
Animals, Vol 14, Iss 15, p 2207 (2024)
The melanocortin 4 receptor (MC4R) gene plays a central role in regulating energy homeostasis and food intake in livestock, thereby affecting their economic worth and growth. In a previous study, the p.T117M mutation in the sheep MC4R gene, which lea
Externí odkaz:
https://doaj.org/article/c277207a85764349b30955ea341c590e
Publikováno v:
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 29 (2023)
Abstract Venomous animals and their venom have always been of human interest because, despite species differences, coevolution has made them capable of targeting key physiological components of our bodies. Respiratory failure from lung injury is one
Externí odkaz:
https://doaj.org/article/bc917c9af3fd4427aeecb060e90d4639
Autor:
Fang-tian Bu, Peng-cheng Jia, Yan Zhu, Ya-ru Yang, Hong-wu Meng, Yi-hui Bi, Cheng Huang, Jun Li
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 26, Iss , Pp 191-206 (2022)
Liver fibrosis is a wound-healing response that results from various chronic damages. If the causes of damage are not removed or effective treatments are not given in a timely manner, it will progress to cirrhosis, even liver cancer. Currently, there
Externí odkaz:
https://doaj.org/article/ab0d40bbd2ac431cbecded088514156f
Publikováno v:
Cells, Vol 13, Iss 1, p 99 (2024)
Amyotrophic Lateral Sclerosis (ALS) is a debilitating neurodegenerative condition characterized by the progressive degeneration of motor neurons. Despite extensive research in various model animals, the cellular signal mechanisms of ALS remain elusiv
Externí odkaz:
https://doaj.org/article/d2bce71faae643c495546b3fd706e0d9
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Akademický článek
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