Zobrazeno 1 - 10
of 395 481
pro vyhledávání: '"cellular and molecular"'
Autor:
Melanie Loix, Sam Vanherle, Marta Turri, Stephan Kemp, Karl J. L. Fernandes, Jerome J. A. Hendriks, Jeroen F. J. Bogie
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-15 (2024)
Abstract Disturbances in the fatty acid lipidome are increasingly recognized as key drivers in the progression of various brain disorders. In this review article, we delve into the impact of Δ9 fatty acid desaturases, with a particular focus on stea
Externí odkaz:
https://doaj.org/article/d0cd345d6a534169b3d87a3b0071d96d
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 11, Pp 11906-11926 (2024)
Schistosomiasis is a parasitic disease that poses a serious threat to human health. However, the pathogenic mechanism during the progression of Schistosoma japonicum infection remains unclear. In order to elucidate this mechanism, we used single-cell
Externí odkaz:
https://doaj.org/article/016b4a0d3d71497ba72c873129900830
Autor:
Lin Wang, Shihang Wang, Hao Yang, Shiwei Li, Xinyu Wang, Yongqi Zhou, Siyuan Tian, Lu Liu, Fang Bai
Publikováno v:
Advanced Science, Vol 11, Iss 40, Pp n/a-n/a (2024)
Abstract The molecular representation model is a neural network that converts molecular representations (SMILES, Graph) into feature vectors, and is an essential module applied across a wide range of artificial intelligence‐driven drug discovery sc
Externí odkaz:
https://doaj.org/article/1fc7fa2285024aa69258be311993ed1d
Publikováno v:
The Egyptian Journal of Internal Medicine, Vol 36, Iss 1, Pp 1-9 (2024)
Abstract Bilirubin is a metabolic product of heme, and an increase in its level may be toxic to the body. It may be conjugated or unconjugated. Encephalopathy is caused by unconjugated bilirubin has the ability to pass through the blood-brain barrier
Externí odkaz:
https://doaj.org/article/8a2b05bbcba94be7b4d3eea930ddcd94
Autor:
Luigi Sansone, Federica Barreca, Manuel Belli, Michele Aventaggiato, Andrea Russo, Giulietta A. Perrone, Matteo A. Russo, Marco Tafani, Andrea Frustaci
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/d390c9eecca3425893ce2e956abb79d7
Autor:
Nora Bloise, Marialaura Giannaccari, Giuseppe Guagliano, Emanuela Peluso, Elisa Restivo, Silvia Strada, Cristina Volpini, Paola Petrini, Livia Visai
Publikováno v:
Cells, Vol 13, Iss 12, p 1054 (2024)
Over the past decade, the development of three-dimensional (3D) models has increased exponentially, facilitating the unravelling of fundamental and essential cellular mechanisms by which cells communicate with each other, assemble into tissues and or
Externí odkaz:
https://doaj.org/article/86e2d87f63fb49ec9cebbfadb5242f9f
Autor:
Luigi Sansone, Federica Barreca, Manuel Belli, Michele Aventaggiato, Andrea Russo, Giulietta A. Perrone, Matteo A. Russo, Marco Tafani, Andrea Frustaci
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionFabry’s disease (FD) is a genetic X-linked systemic and progressive rare disease characterized by the accumulation of globotriaosylceramide (GB3) into the lysosomes of many tissues. FD is due to loss-of-function mutations of α-galactos
Externí odkaz:
https://doaj.org/article/60b1bf9d8cb343589aee61222b849e32
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/c9f9669f17ee4656864438c3d4f5a2e7
Publikováno v:
Bulletin of the National Research Centre, Vol 47, Iss 1, Pp 1-16 (2023)
Abstract Background Parkinson's disease is a neurodegenerative disorder of the central nervous system that is one of the mental disorders that cause tremors, rigidity, and bradykinesia. Many factors determine the development of disease. A comprehensi
Externí odkaz:
https://doaj.org/article/8c0fc344028a44c4814481791cf7f309