Zobrazeno 1 - 10
of 1 700
pro vyhledávání: '"cell-factory"'
Autor:
Zheyi Kuang, Xiaofang Yan, Yanfei Yuan, Ruiqi Wang, Haifan Zhu, Youyang Wang, Jianfeng Li, Jianwen Ye, Haitao Yue, Xiaofeng Yang
Publikováno v:
Synthetic and Systems Biotechnology, Vol 9, Iss 4, Pp 793-808 (2024)
Microorganisms, particularly extremophiles, have evolved multiple adaptation mechanisms to address diverse stress conditions during survival in unique environments. Their responses to environmental coercion decide not only survival in severe conditio
Externí odkaz:
https://doaj.org/article/d694a128eb374db09b0fbbc6c95ff0c9
Publikováno v:
Fungal Biology and Biotechnology, Vol 11, Iss 1, Pp 1-12 (2024)
Abstract Background Aspergillus niger is well-known for its high protein secretion capacity and therefore an important cell factory for homologous and heterologous protein production. The use of a strong promoter and multiple gene copies are commonly
Externí odkaz:
https://doaj.org/article/a09a07198c074f8b85490cb20ecf43c9
Autor:
Jintao Cheng, Zhongji Pu, Jiali Chen, Dingfeng Chen, Baoxian Li, Zhengshun Wen, Yuanxiang Jin, Yanlai Yao, Kan Shao, Xiaosong Gu, Guiling Yang
Publikováno v:
Synthetic and Systems Biotechnology, Vol 10, Iss 1, Pp 120-126 (2025)
(–)-α-Bisabolol is a plant-derived sesquiterpene derived from Eremanthus erythropappus, which can be used as a raw material in cosmetics and has anti-inflammatory function. In this study, we designed six mutation sites of the (–)-α-bisabolol sy
Externí odkaz:
https://doaj.org/article/52eeaf36fb78484ca76bae95c0b02874
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-13 (2024)
Abstract Background Chelerythrine is an important alkaloid used in agriculture and medicine. However, its structural complexity and low abundance in nature hampers either bulk chemical synthesis or extraction from plants. Here, we reconstructed and o
Externí odkaz:
https://doaj.org/article/8b565637b48543a7baea67525bfeb48e
Autor:
Giulia Maria Cattaneo, Ilaria Varotto-Boccazzi, Riccardo Molteni, Federico Ronchetti, Paolo Gabrieli, Jairo Alfonso Mendoza-Roldan, Domenico Otranto, Emanuele Montomoli, Claudio Bandi, Sara Epis
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The development of media for cell culture is a major issue in the biopharmaceutical industry, for the production of therapeutics, immune-modulating molecules and protein antigens. Chemically defined media offer several advantages, as they ar
Externí odkaz:
https://doaj.org/article/c2f19a23ce9d43bf976f7b5c253e91e4
Autor:
Barbara Bourgade, M. Ahsanul Islam
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Thermophilic acetogens are gaining recognition as potent microbial cell factories, leveraging their unique metabolic capabilities to drive the development of sustainable biotechnological processes. These microorganisms, thriving at elevated temperatu
Externí odkaz:
https://doaj.org/article/401b2ec701f442b281d8f3e787e60804
Autor:
Xiang Li, Rongshuai Jiang, Shenghou Wang, Chenyang Li, Yongping Xu, Shuying Li, Qian Li, Liang Wang
Publikováno v:
Frontiers in Chemical Engineering, Vol 6 (2024)
Cordycepin, an adenosine analog, exhibits diverse bioactivities and holds significant potential for applications in healthcare and agriculture. Fungi of the genus Cordyceps, such as Cordyceps militaris, can naturally produce cordycepin. Current sourc
Externí odkaz:
https://doaj.org/article/1a5db0fd80424557b7adb740640d9835
Autor:
Jun-Zhe Zhang, Yu-Zhen Li, Zhi-Ning Xi, Hui-Peng Gao, Quan Zhang, Li-Cheng Liu, Fu-Li Li, Xiao-Qing Ma
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Acetogenic bacteria (acetogens) are a class of microorganisms with conserved Wood-Ljungdahl pathway that can utilize CO and CO2/H2 as carbon source for autotrophic growth and convert these substrates to acetate and ethanol. Acetogens have great poten
Externí odkaz:
https://doaj.org/article/42d52642e7fe47959edeb46866d2347e
Publikováno v:
Biotechnology for Biofuels and Bioproducts, Vol 16, Iss 1, Pp 1-12 (2023)
Abstract Background Microbes have been used as cell factories to synthesize various chemical compounds. Recent advances in synthetic biological technologies have accelerated the increase in the number and capacity of microbial cell factories; the var
Externí odkaz:
https://doaj.org/article/18e17873a9d54683811b09b86ca6d9b7
Autor:
Kai Cao, Fengjie Sun, Zechen Xin, Yujiao Cao, Xiangyu Zhu, Huan Tian, Tong Cao, Jinju Ma, Weidong Mu, Jiankun Sun, Runlong Zhou, Zhengquan Gao, Chunxiao Meng
Publikováno v:
Marine Drugs, Vol 22, Iss 9, p 378 (2024)
Heme, as an essential cofactor and source of iron for cells, holds great promise in various areas, e.g., food and medicine. In this study, the model cyanobacteria Synechocystis sp. PCC6803 was used as a host for heme synthesis. The heme synthesis pat
Externí odkaz:
https://doaj.org/article/1a47bcb711484ce2b58d6192840b6f81