Zobrazeno 1 - 10
of 18 065
pro vyhledávání: '"cell-based"'
Autor:
Gaetan Gavazzi, Marc Paccalin, Quentin Berkovitch, Henri Leleu, Romain Moreau, Emanuele Ciglia, Nansa Burlet, Joaquin Mould-Quevedo
Publikováno v:
Expert Review of Vaccines, Vol 23, Iss 1, Pp 1020-1028 (2024)
Objectives Annually in France, influenza results in over one million GP consultations, around 20,000 hospitalizations, and approximately 9,000 deaths. This study assesses the cost-effectiveness of cell-based quadrivalent influenza vaccine (QIVc) for
Externí odkaz:
https://doaj.org/article/267f95cecd4f4db8b181a4587d0b5693
Publikováno v:
Regenerative Therapy, Vol 27, Iss , Pp 230-233 (2024)
Introduction: Endotoxin is a typical pyrogen derived from the outer membrane of Gram-negative bacteria. In fabricating cell-based medicinal products, it is necessary to control endotoxin in the process and the products. In the quality control tests o
Externí odkaz:
https://doaj.org/article/622e68cd732d42868a3973a33c13c086
Publikováno v:
Expert Review of Vaccines, Vol 23, Iss 1, Pp 371-379 (2024)
Background Cell-based quadrivalent inactivated influenza vaccines (IIV4c) avoid egg-adaptive mutations found in egg-based production, improving vaccine effectiveness (VE). Studies demonstrate improved VE for IIV4c relative to egg-based quadrivalent i
Externí odkaz:
https://doaj.org/article/807c4c3d596840628d18191334031f74
Publikováno v:
Expert Review of Vaccines, Vol 23, Iss 1, Pp 82-87 (2024)
Background Cell-based quadrivalent influenza vaccines (QIVc) can increase effectiveness against seasonal influenza by avoiding mismatch from egg adaption of vaccine viruses. This study evaluates the population-level cost-effectiveness and impacts on
Externí odkaz:
https://doaj.org/article/75c97e014fc449a4872f595eb165ee12
Autor:
Zihao Zhou, Jiarong Zheng, Ye Lu, Zizhao Mai, Yunfan Lin, Pei Lin, Yucheng Zheng, Xu Chen, Rongwei Xu, Xinyuan Zhao, Li Cui
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-21 (2024)
Abstract CD8+ T cells are integral to the effective management of cancer and infectious diseases due to their cytotoxic functions. The efficacy of these cells is profoundly influenced by their metabolic state, which regulates their activation, differ
Externí odkaz:
https://doaj.org/article/bf49ad5f6f5c4284b1e249956fd8cfa5
Establishment of goat mammary organoid cultures modeling the mammary gland development and lactation
Autor:
Lei Jia, Wenying Zhang, Tao Luo, Yongtao Li, Jianhong Shu, Julie Strand, Yuan Yue, Stig Purup, Jianxin Liu, Hengbo Shi
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Background Although several cell culture systems have been developed to investigate the function of the mammary gland in dairy livestock, they have potential limitations, such as the loss of alveolar structure or genetic and phenotypic diffe
Externí odkaz:
https://doaj.org/article/22ad6e048fea46678394a885dd1db017
Autor:
Takumi Saito, Ryo Takatsuji, Goh Murayama, Yu Yamaji, Yukitomo Hagiwara, Yujin Nishioka, Taiga Kuga, Tomoko Miyashita, Makio Kusaoi, Naoto Tamura, Ken Yamaji
Publikováno v:
Immunological Medicine, Vol 47, Iss 4, Pp 264-274 (2024)
Type I interferons (IFN-Is) play a significant role in systemic lupus erythematosus (SLE) pathogenesis. Double-filtration plasmapheresis (DFPP) is a treatment option for SLE; however, its effect on IFN-Is remains unclear. Therefore, we investigated t
Externí odkaz:
https://doaj.org/article/f27e8e2e68fc4fa0ad5b2806c3934536
Autor:
Masatoshi Murayama, Simon K. Chow, Max L. Lee, Bill Young, Yasemin S. Ergul, Issei Shinohara, Yosuke Susuki, Masakazu Toya, Qi Gao, Stuart B. Goodman
Publikováno v:
Bone & Joint Research, Vol 13, Iss 9, Pp 462-473 (2024)
Bone regeneration and repair are crucial to ambulation and quality of life. Factors such as poor general health, serious medical comorbidities, chronic inflammation, and ageing can lead to delayed healing and nonunion of fractures, and persistent bon
Externí odkaz:
https://doaj.org/article/7e07d74a61e74f8081ab24fb0cb29b67
Autor:
N. K. Ossina, L. T. Volova, P. A. Lebedev, I. A. Shafieva, E. I. Pugachev, S. A. Goncharenko, S. I. Kuznetsov, O. A. Gusyakova, G. N. Svetlova
Publikováno v:
Медицинская иммунология, Vol 26, Iss 5, Pp 897-904 (2024)
Currently, gouty arthritis is considered as a polygenic multifactorial autoinflammatory disease caused by activation of the NOD (nucleotide-binding domain) -like protein receptor 3 inflammasome NLRP3. The two cytokines IL-1β and IL-18 are considered
Externí odkaz:
https://doaj.org/article/3b0c34c471cf4bb68546721cdedfce49
Publikováno v:
Journal of Rare Diseases, Vol 3, Iss 1, Pp 1-12 (2024)
Abstract Background Cystic fibrosis (CF) is a fatal genetic disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, disrupting ion transport. This results in organ damage and reduced life expectancy. Main
Externí odkaz:
https://doaj.org/article/cc996d71d27642d39fded2328e3086c3