Výsledky vyhledávání - "cell regulation"

Akademický článek

Mechanistic insights and therapeutic applications of Hinokitiol in Inflammation, Antimicrobial therapy, and Cancer

Autor: Karthik K Karunakar, Binoy Varghese Cheriyan, Ramaiyan Velmurugan, Meenaloshini Gopalakrishnan, Karthikha VS

Publikováno v: Pharmacological Research - Modern Chinese Medicine, Vol 13, Iss , Pp 100527- (2024)

Background: Hinokitiol (β-thujaplicin), a naturally occurring tropolone derivative, exhibits multifaceted pharmacological properties. The aim of this review is to explore the medicinal potential of hinokitiol in different biological systems. Objecti

Externí odkaz: https://doaj.org/article/2d4a9f20f6d44ad59d67c27e4c49e1b9

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Akademický článek

Germline natural killer cell receptors modulating the T cell response

Autor: Laura Mora-Bitria, Becca Asquith

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

In addition to their central role during innate responses, NK cells regulate adaptive immunity through various mechanisms. A wide array of innate receptors has been involved in the NK cell regulatory function. However, the clinical implications of th

Externí odkaz: https://doaj.org/article/3c840ebf4b5e47fb963966a1bb047bd7

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Akademický článek

Abnormal late postprandial glucagon response in type 1 diabetes is a function of differences in stimulated C-peptide concentrations

Autor: Lingyu Zhang, Yao Qin, Yiting Huang, Qizhen Hu, Qian Wu, Xing Wang, Mei Zhang

Publikováno v: Frontiers in Endocrinology, Vol 15 (2024)

BackgroundThe functional changes in alpha cells in patients with type 1 diabetes (T1D) with different residual beta cell functions remain poorly elucidated. The study aimed to investigate the relationship between glucagon secretion and C-peptide leve

Externí odkaz: https://doaj.org/article/2eff49e8b71c49ee884e9ef260b47d5f

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Akademický článek

How aging influences the gut-bone marrow axis and alters hematopoietic stem cell regulation

Autor: Christopher Wells, Tristan Robertson, Prameet Sheth, Sheela Abraham

Publikováno v: Heliyon, Vol 10, Iss 12, Pp e32831- (2024)

The gut microbiome has come to prominence across research disciplines, due to its influence on major biological systems within humans. Recently, a relationship between the gut microbiome and hematopoietic system has been identified and coined the gut

Externí odkaz: https://doaj.org/article/b48eb1f3f78b43b59bfe94dd70e0238e

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Akademický článek

Deciphering the shift from benign to active relapsing-remitting multiple sclerosis: Insights into T regulatory cell dysfunction and apoptosis regulation

Autor: Anat Achiron, Rina Falb, Shay Menascu, David Magalashvili, Mathilda Mandel, Polina Sonis, Michael Gurevich

Publikováno v: Neurobiology of Disease, Vol 194, Iss , Pp 106475- (2024)

Background: Relapsing-remitting multiple sclerosis (RRMS), a common demyelinating disease among young adults, follows a benign course in 10–15% of cases, where patients experience minimal neurological disability for a decade following disease onset

Externí odkaz: https://doaj.org/article/cb619171740a4b848d0ab39a9a155a62

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