Zobrazeno 1 - 10
of 64
pro vyhledávání: '"cell nonautonomous"'
Autor:
Prashant Kumar, Fahad Zadjali, Ying Yao, Daniel Johnson, Brian Siroky, Aristotelis Astrinidis, Peter Vogel, Kenneth W. Gross, John J. Bissler
Publikováno v:
Genes and Diseases, Vol 9, Iss 1, Pp 187-200 (2022)
TSC renal cystic disease is poorly understood and has no approved treatment. In a new principal cell-targeted murine model of Tsc cystic disease, the renal cystic epithelium is mostly composed of type A intercalated cells with an intact Tsc2 gene con
Externí odkaz:
https://doaj.org/article/e9af695b73a243cab858e93e553b7277
Publikováno v:
Frontiers in Aging, Vol 3 (2022)
In multicellular organisms such as Caenorhabditis elegans, cellular stress stimuli and responses are communicated between tissues to promote organismal health- and lifespan. The nervous system is the predominant regulator of cell nonautonomous proteo
Externí odkaz:
https://doaj.org/article/6f14b9fa8dce49edae4d4d294044d308
Autor:
Patricija van Oosten-Hawle
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 251 (2023)
Heat shock protein 90 (Hsp90) is a highly conserved molecular chaperone that assists in the maturation of many client proteins involved in cellular signal transduction. As a regulator of cellular signaling processes, it is vital for the maintenance o
Externí odkaz:
https://doaj.org/article/91fc8439cd8541c49054729e44bde5cf
Autor:
Madhivanan, Kayalvizhi, Greiner, Erin R., Alves-Ferreira, Miguel, Soriano-Castell, David, Rouzbeh, Nirvan, Aguirre, Carlos A., Paulsson, Johan F., Chapman, Justin, Jiang, Xin, Ooi, Felicia K., Lemos, Carolina, Dillin, Andrew, Prahlad, Veena, Kelly, Jeffery W., Encalada, Sandra E.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2018 Aug . 115(33), E7710-E7719.
Externí odkaz:
https://www.jstor.org/stable/26530269
Autor:
Aristotelis Astrinidis, John J. Bissler, Ying Yao, Fahad Zadjali, Daniel L. Johnson, Prashant Kumar, Kenneth W. Gross, Peter Vogel, Brian Siroky
Publikováno v:
Genes and Diseases, Vol 9, Iss 1, Pp 187-200 (2022)
Genes & Diseases
Genes & Diseases
TSC renal cystic disease is poorly understood and has no approved treatment. In a new principal cell-targeted murine model of Tsc cystic disease, the renal cystic epithelium is mostly composed of type A intercalated cells with an intact Tsc2 gene con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30778696e06d508bbfe267757da40013
https://doi.org/10.1016/j.gendis.2021.03.010
https://doi.org/10.1016/j.gendis.2021.03.010
Tese de doutoramento em Ciências da Saúde
O envelhecimento é um fenómeno biológico complexo que no sentido mais lato pode ser definido como uma perda estocástica de funcionalidade dos organismos vivos ao longo do tempo. O envelhecimento po
O envelhecimento é um fenómeno biológico complexo que no sentido mais lato pode ser definido como uma perda estocástica de funcionalidade dos organismos vivos ao longo do tempo. O envelhecimento po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______307::e77f7e7dff949c7329b3732a0b36680a
https://hdl.handle.net/1822/78444
https://hdl.handle.net/1822/78444
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Rebecca C. Taylor, Claudio Hetz
Publikováno v:
Aging Cell
The aging process is characterized by a progressive decline in the function of most tissues, representing the main risk factor in the development of a variety of human diseases. Studies in multiple animal models have demonstrated that interventions t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4a2b0d8ee807a729a8b67d37393f919
https://doi.org/10.1111/acel.13265
https://doi.org/10.1111/acel.13265
Autor:
Elisa Enriquez-Hesles, Margaret B. Wierman, Ryan D. Fine, Sean M. Santos, Daniel L. Smith, Nazif Maqani, James R. Bain, Agata Kalita, Matthew D. Hirschey, Matthew D. Sutcliffe, Jeffrey S. Smith, John L. Hartman, Kevin A. Janes, Michael J. Muehlbauer
Publikováno v:
The Journal of Biological Chemistry
Caloric restriction (CR) improves health span and life span of organisms ranging from yeast to mammals. Understanding the mechanisms involved will uncover future interventions for aging-associated diseases. In budding yeast, Saccharomyces cerevisiae,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86c7c1c9266dc964189fb3241f15bac4
https://pubmed.ncbi.nlm.nih.gov/33243834
https://pubmed.ncbi.nlm.nih.gov/33243834