Zobrazeno 1 - 10
of 166
pro vyhledávání: '"cell lineage tracing"'
Autor:
Toshihide Mizoguchi
Publikováno v:
Japanese Dental Science Review, Vol 60, Iss , Pp 109-119 (2024)
Bone tissue provides structural support for our bodies, with the inner bone marrow (BM) acting as a hematopoietic organ. Within the BM tissue, two types of stem cells play crucial roles: mesenchymal stem cells (MSCs) (or skeletal stem cells) and hema
Externí odkaz:
https://doaj.org/article/cb6b5dfa805441a6ba35a2adcc717353
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-14 (2022)
Abstract Background DCLEAR is an R package used for single cell lineage reconstruction. The advances of CRISPR-based gene editing technologies have enabled the prediction of cell lineage trees based on observed edited barcodes from each cell. However
Externí odkaz:
https://doaj.org/article/689f5a5067d742eb825770955795380d
Autor:
Ida Larsson, Erika Dalmo, Ramy Elgendy, Mia Niklasson, Milena Doroszko, Anna Segerman, Rebecka Jörnsten, Bengt Westermark, Sven Nelander
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 9, Pp 1-19 (2021)
Abstract Tumor cell heterogeneity is a crucial characteristic of malignant brain tumors and underpins phenomena such as therapy resistance and tumor recurrence. Advances in single‐cell analysis have enabled the delineation of distinct cellular stat
Externí odkaz:
https://doaj.org/article/65c2adc5f7ff4fcfb10d205bdc3d16b7
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 4, Pp 1-24 (2021)
Abstract Elucidating the chromatin dynamics that orchestrate embryogenesis is a fundamental question in developmental biology. Here, we exploit position effects on expression as an indicator of chromatin activity and infer the chromatin activity land
Externí odkaz:
https://doaj.org/article/5c6c424453944d598d638ac5b22ec142
Publikováno v:
Frontiers in Surgery, Vol 9 (2022)
Cell lineage tracing and single-cell sequencing have been widely applied in development biology and oncology to reveal the molecular mechanisms in multiple basic biological processes and the differentiation of stem cells, as well as quantify the diff
Externí odkaz:
https://doaj.org/article/b8bae09083244bafabb79bf335d26a29
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Michael Fenlon, Celia Short, Jiabo Xu, Nicolas Malkoff, Elaa Mahdi, Michelle Hough, Alison Glazier, Calvin Lee, Kinji Asahina, Kasper S. Wang
Publikováno v:
Physiological Reports, Vol 8, Iss 14, Pp n/a-n/a (2020)
Abstract Cholestatic liver injury is associated with intrahepatic biliary fibrosis, which can progress to cirrhosis. Resident hepatic progenitor cells (HPCs) expressing Prominin‐1 (Prom1 or CD133) become activated and participate in the expansion o
Externí odkaz:
https://doaj.org/article/53d2a788a1054b1bbc240ff50eae74e2
Publikováno v:
Cells, Vol 11, Iss 4, p 722 (2022)
Adult neural stem cells (aNSCs) are the source for the continuous production of new neurons throughout life. This so-called adult neurogenesis has been extensively studied; the intermediate cellular stages are well documented. Recent discoveries have
Externí odkaz:
https://doaj.org/article/6aaa02b123fc48a691d16c97d77d7af9