Zobrazeno 1 - 10
of 194
pro vyhledávání: '"cell intrinsic"'
Autor:
Zinat Sharmin, Kehua Jin, Ai-Yu Gong, Silu Deng, Chansorena Pok, Marion L. Graham, Shuhong Wang, Nicholas W. Mathy, Annemarie Shibata, Xian-Ming Chen
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Intestinal epithelial cells possess the requisite molecular machinery to initiate cell-intrinsic defensive responses against intracellular pathogens, including intracellular parasites. Interferons(IFNs) have been identified as cornerstones of epithel
Externí odkaz:
https://doaj.org/article/08639b7b6277458cbbca556868d87ac1
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Metabolic shifts can occur in cells of the innate immune system in response to microbial infection. Whether these metabolic shifts benefit host defense and propagation of an immune response appears to be context dependent. In an arms race, host-adapt
Externí odkaz:
https://doaj.org/article/e7daf09d049c4970b6b3c9a3b39ddb4b
Autor:
Tian-You Cheng, Ya-Juan Liu, Hong Yan, Yi-Bo Xi, Li-Qiang Duan, Yang Wang, Tian-Tian Zhang, Yin-Min Gu, Xiao-Dong Wang, Chang-Xin Wu, Shan Gao
Publikováno v:
Cells, Vol 11, Iss 24, p 4021 (2022)
B and T lymphocyte attenuator (BTLA) is an immune checkpoint molecule that mediates the escape of tumor cells from immunosurveillance. Consequently, BTLA and its ligand herpesvirus entry mediator (HVEM) are potentially immunotherapeutic targets. Howe
Externí odkaz:
https://doaj.org/article/0456426b906b4e199c54fce582c50cf5
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
In the absence of effective vaccines and treatments, annual outbreaks of severe human haemorrhagic fever caused by arenaviruses, such as Lassa virus, continue to pose a significant human health threat. Understanding the balance of cellular factors th
Externí odkaz:
https://doaj.org/article/91a8243280c1497695da0220a5cd1aa4
Autor:
Yanmei Wang, Jihan Lyu, Xiaoqing Qian, Binjun Chen, Haojie Sun, Wenwei Luo, Fanglu Chi, Hongzhe Li, Dongdong Ren
Publikováno v:
Biology, Vol 12, Iss 4, p 625 (2023)
Dentin matrix protein 1 (Dmp1) is a highly phosphorylated, extracellular matrix protein that is extensively expressed in bone and teeth but also found in soft tissues, including brain and muscle. However, the functions of Dmp1 in the mice cochlea are
Externí odkaz:
https://doaj.org/article/08f8289d4f1d4b018aecff7390b88e33
Akademický článek
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Autor:
Tao Peng, Khamsone Phasouk, Catherine N. Sodroski, Sijie Sun, Yon Hwangbo, Erik D. Layton, Lei Jin, Alexis Klock, Kurt Diem, Amalia S. Magaret, Lichen Jing, Kerry Laing, Alvason Li, Meei-Li Huang, Max Mertens, Christine Johnston, Keith R. Jerome, David M. Koelle, Anna Wald, David M. Knipe, Lawrence Corey, Jia Zhu
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Tissue-resident-memory T cells (TRM) populate the body’s barrier surfaces, functioning as frontline responders against reencountered pathogens. Understanding of the mechanisms by which CD8TRM achieve effective immune protection remains incomplete i
Externí odkaz:
https://doaj.org/article/8a1eece0c94043338e4530333d1db25a
Publikováno v:
Molecular & Cellular Oncology, Vol 6, Iss 2, Pp 1-4 (2019)
Loss of excision repair cross-complementation group 1 (ERCC1), frequently found in lung cancer, and mutations in breast cancer type 1/2 susceptibility genes (BRCA1/2), often found in ovarian, breast and prostate cancers, confer sensitivity to poly-(A
Externí odkaz:
https://doaj.org/article/d47bb605b76545a88a86206288006b5b
Akademický článek
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Akademický článek
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