Zobrazeno 1 - 10
of 1 822
pro vyhledávání: '"cell homeostasis"'
Autor:
Dohnke, Sebastian, Moehser, Stephanie, Surnov, Alexey, Kurth, Thomas, Jessberger, Rolf, Kretschmer, Karsten, Garbe, Annette I.
In T cells, processes such as migration and immunological synapse formation are accompanied by the dynamic reorganization of the actin cytoskeleton, which has been suggested to be mediated by regulators of RhoGTPases and by F-actin bundlers. SWAP-70
Externí odkaz:
https://tud.qucosa.de/id/qucosa%3A91929
https://tud.qucosa.de/api/qucosa%3A91929/attachment/ATT-0/
https://tud.qucosa.de/api/qucosa%3A91929/attachment/ATT-0/
Autor:
Nannan Sun, Mengmeng Zhang, Jingjing Kong, Jin Li, Yong Dong, Xiaoqian Wang, Liyan Fu, Yiwei Zhou, Yaoyao Chen, Yingmei Li, Xianlei Sun, Rongqun Guo
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35775- (2024)
Aplastic anemia (AA) is an autoimmune hematopoietic disease mediated by autoreactive T cells leading to bone marrow failure. However, the precise role of autoreactive T cells in the development of AA is not fully understood, hindering the advancement
Externí odkaz:
https://doaj.org/article/cc3cc2523b4c4587be54684cb3e6c172
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionIn vivo T cell migration has been of interest to scientists for the past 60 years. T cell kinetics are important in the understanding of the immune response to infectious agents. More recently, adoptive T cell therapies have proven to be
Externí odkaz:
https://doaj.org/article/104efaa5aded44e295627f1eaa31bc94
Autor:
Rosanna Culurciello, Ilaria Di Nardo, Andrea Bosso, Francesca Tortora, Romualdo Troisi, Filomena Sica, Angela Arciello, Eugenio Notomista, Elio Pizzo
Publikováno v:
Heliyon, Vol 10, Iss 3, Pp e24556- (2024)
Human angiogenin (hANG) is the most studied stress-induced ribonuclease (RNase). In physiological conditions it performs its main functions in nucleoli, promoting cell proliferation by rDNA transcription, whereas it is strongly limited by its inhibit
Externí odkaz:
https://doaj.org/article/b23113ca23a04c4199aeae3934dd997b
Autor:
José M. Benito, Daniel Jiménez-Carretero, Clara Restrepo, José M. Ligos, Jaime Valentín-Quiroga, Ignacio Mahillo, Alfonso Cabello, Eduardo López-Collazo, Fátima Sánchez-Cabo, Miguel Górgolas, Vicente Estrada, Norma Rallón
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5937 (2024)
Elite controllers (ECs) are people living with HIV (PLWH) able to control HIV replication without antiretroviral therapy and have been proposed as a model of a functional HIV cure. Much evidence suggests that this spontaneous control of HIV has a cos
Externí odkaz:
https://doaj.org/article/a51c172248724682b4805792705b6363
Publikováno v:
Cells, Vol 13, Iss 7, p 576 (2024)
Blood cells in Drosophila serve primarily innate immune responses. Various stressors influence blood cell homeostasis regarding both numbers and the proportion of blood cell types. The principle molecular mechanisms governing hematopoiesis are conser
Externí odkaz:
https://doaj.org/article/e1fd3c4944bc4f37a55079230916b087
Publikováno v:
Autophagy Reports, Vol 1, Iss 1, Pp 381-384 (2022)
Aberrant production of reactive oxygen species (ROS) from dysfunctional mitochondria leads to oxidative stress and DNA damage, which induces the cellular senescence stress response pathway. This, while exerting strong beneficial suppressive effects o
Externí odkaz:
https://doaj.org/article/a0b54d8f5cba41188b29de16b455bc8b
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/c4f2941d35cc4e7e8376c01636600f6f
Autor:
Jia Song, Xin Zhang, Yue Yin, Mengfan Guo, Xuyang Zhao, Likun Wang, Caixia Ren, Yuxin Yin, Xuehui Zhang, Xuliang Deng, Dan Lu
Publikováno v:
Advanced Science, Vol 10, Iss 11, Pp n/a-n/a (2023)
Abstract The peripheral T cell pool is maintained at dynamic homeostasis through fine‐tuning of thymic output and self‐renewal of naïve T cells. Lymphopenia or reduced lymphocyte number is implicated in autoimmune diseases, yet little is known a
Externí odkaz:
https://doaj.org/article/2189e4ea77284ef3a45bba4a60833168
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