Zobrazeno 1 - 10
of 2 268
pro vyhledávání: '"cell entry"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of Johne’s Disease, a chronic granulomatous enteritis of ruminants. MAP establishes an infection in the host via the small intestine. This requires the bacterium
Externí odkaz:
https://doaj.org/article/79068f4047b7441cab0184a44487cb39
Autor:
Yasuteru Sakurai, Sayaka Okada, Takehiro Ozeki, Rokusuke Yoshikawa, Takaaki Kinoshita, Jiro Yasuda
Publikováno v:
mSphere, Vol 9, Iss 9 (2024)
ABSTRACT The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant exhibits high transmissibility with a strong immune escape ability and causes frequent large-scale global infections by producing predominant subvariants. Here,
Externí odkaz:
https://doaj.org/article/2c21bf4367004375b5731661305a40d6
Autor:
Kathleen Boesze-Battaglia, Gary H. Cohen, Paul F. Bates, Lisa M. Walker, Ali Zekavat, Bruce J. Shenker
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Aggregatibacter actinomycetemcomitans cytolethal distending toxin (Cdt) is capable of intoxicating lymphocytes macrophages, mast cells and epithelial cells. Following Cdt binding to cholesterol, in the region of membrane lipid rafts, the CdtB and Cdt
Externí odkaz:
https://doaj.org/article/b4dc70dc12ab4fc7a84cf22c58d7d983
Publikováno v:
Cell Insight, Vol 3, Iss 1, Pp 100144- (2024)
The global outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) threatened human health and public safety. The development of anti-SARS-CoV-2 therapies have been essential to curb the spread of SARS-CoV-2. Particularly, antivi
Externí odkaz:
https://doaj.org/article/1dbb426afa404669b08fea1d2097000b
Autor:
Endrit Shahini, Antonella Argentiero, Alessandro Andriano, Francesco Losito, Marcello Maida, Antonio Facciorusso, Raffaele Cozzolongo, Erica Villa
Publikováno v:
Medicina, Vol 60, Iss 6, p 998 (2024)
Hepatitis E virus (HEV) infection is typically a self-limiting, acute illness that spreads through the gastrointestinal tract but replicates in the liver. However, chronic infections are possible in immunocompromised individuals. The HEV virion has t
Externí odkaz:
https://doaj.org/article/bf69f86049c5431cb73d7e51cada56bc
Autor:
Lu Zhang, Alexandra Dopfer-Jablonka, Inga Nehlmeier, Amy Kempf, Luise Graichen, Noemí Calderón Hampel, Anne Cossmann, Metodi V. Stankov, Gema Morillas Ramos, Sebastian R. Schulz, Hans-Martin Jäck, Georg M. N. Behrens, Stefan Pöhlmann, Markus Hoffmann
Publikováno v:
Vaccines, Vol 12, Iss 5, p 487 (2024)
Transmissibility and immune evasion of the recently emerged, highly mutated SARS-CoV-2 BA.2.87.1 are unknown. Here, we report that BA.2.87.1 efficiently enters human cells but is more sensitive to antibody-mediated neutralization than the currently d
Externí odkaz:
https://doaj.org/article/cd69a4083c014053bc288930db5d3c65
Autor:
Revansiddha H. Katte, Yuanyun Ao, Wang Xu, Yang Han, Guohua Zhong, Dibya Ghimire, Jon Florence, Torry A. Tucker, Maolin Lu
Publikováno v:
Viruses, Vol 16, Iss 3, p 391 (2024)
The surface spike (S) glycoprotein mediates cell entry of SARS-CoV-2 into the host through fusion at the plasma membrane or endocytosis. Omicron lineages/sublineages have acquired extensive mutations in S to gain transmissibility advantages and alter
Externí odkaz:
https://doaj.org/article/6c133e0c09264f378e3710df8ec91a44
Autor:
Wenfang Spring Tan, Enguang Rong, Inga Dry, Simon Lillico, Andy Law, Paul Digard, Bruce Whitelaw, Robert G. Dalziel
Publikováno v:
Viruses, Vol 16, Iss 2, p 297 (2024)
To identify host factors that affect Bovine Herpes Virus Type 1 (BoHV-1) infection we previously applied a genome wide CRISPR knockout screen targeting all bovine protein coding genes. By doing so we compiled a list of both pro-viral and anti-viral p
Externí odkaz:
https://doaj.org/article/92554c5a6aef4e69a1b87f7073f7b160
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