Apical contacts stemming from incomplete delamination guide progenitor cell allocation through a dragging mechanism

Autor: Eduardo Pulgar, Cornelia Schwayer, Néstor Guerrero, Loreto López, Susana Márquez, Steffen Härtel, Rodrigo Soto, Carl-Philipp Heisenberg, Miguel L Concha

Publikováno v: eLife, Vol 10 (2021)

The developmental strategies used by progenitor cells to allow a safe journey from their induction place towards the site of terminal differentiation are still poorly understood. Here, we uncovered a mechanism of progenitor cell allocation that stems

Externí odkaz: https://doaj.org/article/14e379a718f14f0eab4658e1ac491154

Mutations in the Drosophila tricellular junction protein M6 synergize with Ras V12 to induce apical cell delamination and invasion

Autor: Dunn, Brandon S., Rush, Lindsay, Lu, Jin-Yu, Xu, Tian

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2018 Aug . 115(33), 8358-8363.

Externí odkaz: https://www.jstor.org/stable/26530243

Twist1 interacts with beta/delta-Catenins during neural tube development and regulates fate transition in cranial neural crest cells

Autor: Jessica W. Bertol, Shelby Johnston, Rabia Ahmed, Victoria K. Xie, Kelsea M. Hubka, Lissette Cruz, Larissa Nitschke, Marta Stetsiv, Jeremy P. Goering, Paul Nistor, Sally Lowell, Hanne Hoskens, Peter Claes, Seth M. Weinberg, Irfan Saadi, Mary C. Farach-Carson, Walid D. Fakhouri

Publikováno v: Bertol, J W, Johnston, S, Ahmed, R, Xie, V K, Hubka, K M, Cruz, L, Nitschke, L, Stetsiv, M, Goering, J P, Nistor, P, Lowell, S, Hoskens, H, Claes, P, Weinberg, S M, Saadi, I, Farach-Carson, M C & Fakhouri, W D 2022, ' Twist1 interacts with beta/delta-Catenins during neural tube development and regulates fate transition in cranial neural crest cells ', Development, vol. 149, no. 15, dev200068 . https://doi.org/10.1242/dev.200068

Cell fate determination is a necessary and tightly regulated process for producing different cell types and structures during development. Cranial neural crest cells (CNCCs) are unique to vertebrate embryos and emerge from the neural plate borders in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4231605d112a6519e68db0c128687524
https://www.pure.ed.ac.uk/ws/files/288868363/dev200068.pdf

Apical contacts stemming from incomplete delamination guide progenitor cell allocation through a dragging mechanism

Autor: Rodrigo Soto, Eduardo Pulgar, Susana Márquez, Loreto López, Steffen Härtel, Cornelia Schwayer, Miguel L. Concha, Carl-Philipp Heisenberg, Néstor Guerrero

Publikováno v: eLife, Vol 10 (2021)

The developmental strategies used by progenitor cells to endure a safe journey from their induction place towards the site of terminal differentiation are still poorly understood. Here we uncovered a progenitor cell allocation mechanism that stems fr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45534c1a714ea547e2885e24fc6e01ac
https://elifesciences.org/articles/66483

Neogenin-loss in neural crest cells results in persistent hyperplastic primary vitreous formation

Autor: Sen Lin, Lin Mei, Wei Liu, Lei Li, Jian Ye, Chun-Lin Chen, Dong Sun, Jin-Xia Hu, Wen Cheng Xiong

Publikováno v: Journal of Molecular Cell Biology

Neogenin is a transmembrane receptor critical for multiple cellular processes, including neurogenesis, astrogliogenesis, endochondral bone formation, and iron homeostasis. Here we present evidence that loss of neogenin contributes to pathogenesis of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef250f4affd936c993a8cc7daa1c1d9c
https://doi.org/10.1093/jmcb/mjz076