Zobrazeno 1 - 10
of 382
pro vyhledávání: '"cell composition"'
Autor:
Krasimira Aleksandrova, Jana Leise, Christoph Priesner, Murat Aktas, Michael Apel, Mario Assenmacher, Iris Bürger, Anne Richter, Pia Altefrohne, Christine Schubert, Astrid Holzinger, Markus Barden, Valerie Bezler, Michael von Bergwelt-Baildon, Peter Borchmann, Lilia Goudeva, Wolfgang Glienke, Lubomir Arseniev, Ruth Esser, Hinrich Abken, Ulrike Koehl
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionPoint-of-care (POC) manufacturing of chimeric antigen receptor (CAR) modified T cell has expanded rapidly over the last decade. In addition to the use of CD19 CAR T cells for hematological diseases, there is a growing interest in targetin
Externí odkaz:
https://doaj.org/article/f6589c518506495e91a9217ebb7da6b4
Publikováno v:
Clinical, Cosmetic and Investigational Dermatology, Vol Volume 16, Pp 3413-3426 (2023)
Chen-Xi Zhao, Shi-Lei Wang, Hai-Xia Li, Xin Li Department of Cosmetology and Dermatology, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, 400021, People’s Republic of ChinaCorrespondence: Xin Li, Department of Cosmetology and Dermato
Externí odkaz:
https://doaj.org/article/121f636dacde430b9bb6ecbfe505e24a
Publikováno v:
BMC Medical Genomics, Vol 16, Iss S2, Pp 1-17 (2023)
Abstract Background Cell composition deconvolution (CCD) is a type of bioinformatic task to estimate the cell fractions from bulk gene expression profiles, such as RNA-seq. Many CCD models were developed to perform linear regression analysis using re
Externí odkaz:
https://doaj.org/article/8c8d6b672d5d4def8b25bab716326e0a
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
As a crucial component of the male reproductive system, the epididymis plays multiple roles, including sperm storage and secretion of nutritive fluids for sperm development and maturation. The acquisition of fertilization capacity by sperm occurs dur
Externí odkaz:
https://doaj.org/article/5d460f37237843f886c3c8c4888ba818
Autor:
Olga V. Burenkova, Oksana Yu. Naumova, Jessica A. Church, Jenifer Juranek, Jack M. Fletcher, Elena L. Grigorenko
Publikováno v:
Comprehensive Psychoneuroendocrinology, Vol 17, Iss , Pp 100223- (2024)
Background: The biological embedding theory posits that early life experiences can lead to enduring physiological and molecular changes impacting various life outcomes, notably academic performance. Studying previously revealed and objective biomarke
Externí odkaz:
https://doaj.org/article/7c6a6609ade34e339a05d31838127d1a
Autor:
Xian Shi, Minghan Qu, Yi Jiang, Ziwei Zhu, Chengguqiu Dai, Minghui Jiang, Lin Ding, Yu Yan, Chaolong Wang, Xiaomin Zhang, Shanshan Cheng, Xingjie Hao
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-11 (2023)
Abstract Background Although immune cells are involved in acute coronary syndrome (ACS), few studies have explored the association of incident ACS with the relative immune cell proportions. We aimed to investigate the association of immune cell propo
Externí odkaz:
https://doaj.org/article/bb42eb4f81bc4d749a7d5f8acb0fb703
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background Variation in cell composition can dramatically impact analyses in bulk tissue samples. A commonly employed approach to mitigate this issue is to adjust statistical models using estimates of cell abundance derived directly from omi
Externí odkaz:
https://doaj.org/article/87c277d2929745d1b8453c534ea2d91b
Autor:
Hui Feng, Tingyin Feng, Yidi Mo, Suli Sun, Lu Wang, Chunbin Lu, Chengli Feng, Ke Xing, Zhijian Su
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Among the artiodactyls, male animals belonging to the Family Moschidae have a unique tissue, the musk gland, with the capability of musk synthesis. However, the genetic basis of musk gland formation and musk production are still poorly understood. He
Externí odkaz:
https://doaj.org/article/26ab09ae037c4016b1c727a6af0d0d85
Autor:
Terri Clister, Rosalyn M. Fey, Zachary R. Garrison, Cristian D. Valenzuela, Anna Bar, Justin J. Leitenberger, Rajan P. Kulkarni
Publikováno v:
Cells, Vol 13, Iss 3, p 266 (2024)
Healthy human skin tissue is often used as a control for comparison to diseased skin in patients with skin pathologies, including skin cancers or other inflammatory conditions such as atopic dermatitis or psoriasis. Although non-affected skin from th
Externí odkaz:
https://doaj.org/article/1fade0e795d8433eaebe867b965f2f5d
Autor:
Rushan Sulimanov, Konstantin Koshelev, Vladimir Makarov, Alexandre Mezentsev, Mikhail Durymanov, Lilian Ismail, Komal Zahid, Yegor Rumyantsev, Ilya Laskov
Publikováno v:
Life, Vol 13, Iss 11, p 2228 (2023)
Mathematical models of non-small-cell lung cancer are powerful tools that use clinical and experimental data to describe various aspects of tumorigenesis. The developed algorithms capture phenotypic changes in the tumor and predict changes in tumor b
Externí odkaz:
https://doaj.org/article/916375df65fc4699ac4b8972e1bd8a5d