Integrated single-cell analysis reveals distinct epigenetic-regulated cancer cell states and a heterogeneity-guided core signature in tamoxifen-resistant breast cancer.

Autor: Fang K; Data Science Institute, MCW Cancer Center and Mellowes Center for Genome Science and Precision Medicine, Medical College of Wisconsin, Milwaukee, WI, 53226, USA., Ohihoin AG; Cell and Developmental Biology PhD Program, Medical College of Wisconsin, Milwaukee, WI, 53226, USA., Liu T; Data Science Institute, MCW Cancer Center and Mellowes Center for Genome Science and Precision Medicine, Medical College of Wisconsin, Milwaukee, WI, 53226, USA., Choppavarapu L; Data Science Institute, MCW Cancer Center and Mellowes Center for Genome Science and Precision Medicine, Medical College of Wisconsin, Milwaukee, WI, 53226, USA., Nosirov B; Department of Cancer Research, Luxembourg Institute of Health, NORLUX Neuro-Oncology Laboratory and Multiomics Data Science Research Group, Strassen, L-1445, Luxembourg., Wang Q; Department of Pathology and Duke Cancer Institute, Duke University, Durham, NC, 27710, USA., Yu XZ; Department of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, WI, 53226, USA., Kamaraju S; Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, 53226, USA., Leone G; Department of Pathology and MCW Cancer Center, Medical College of Wisconsin, Milwaukee, WI, 53226, USA., Jin VX; Data Science Institute, MCW Cancer Center and Mellowes Center for Genome Science and Precision Medicine, Medical College of Wisconsin, Milwaukee, WI, 53226, USA. vjin@mcw.edu.

Publikováno v: Genome medicine [Genome Med] 2024 Nov 18; Vol. 16 (1), pp. 134. Date of Electronic Publication: 2024 Nov 18.

Highly sensitive microfluidic sensor using integrated optical fiber and real-time single-cell Raman spectroscopy for diagnosis of pancreatic cancer.

Autor: Ni R; Health Science Center, Ningbo University, Ningbo, 315211, China., Ge K; Key Laboratory of Photoelectric Materials and Devices of Zhejiang Province, Ningbo University, Ningbo, 315211, China; Engineering Research Center for Advanced Infrared Photoelectric Materials and Devices of Zhejiang Province, Ningbo University, Ningbo, 315211, China., Luo Y; Health Science Center, Ningbo University, Ningbo, 315211, China., Zhu T; Health Science Center, Ningbo University, Ningbo, 315211, China., Hu Z; Health Science Center, Ningbo University, Ningbo, 315211, China., Li M; College of Information Science and Engineering, Ningbo University, Ningbo, 315211, China., Tao P; Key Laboratory of Photoelectric Materials and Devices of Zhejiang Province, Ningbo University, Ningbo, 315211, China; Engineering Research Center for Advanced Infrared Photoelectric Materials and Devices of Zhejiang Province, Ningbo University, Ningbo, 315211, China., Chi J; Health Science Center, Ningbo University, Ningbo, 315211, China., Li G; Health Science Center, Ningbo University, Ningbo, 315211, China; The First Affiliated Hospital of Ningbo University, Ningbo, 315020, China., Yuan H; College of Information Science and Engineering, Ningbo University, Ningbo, 315211, China., Pang Q; Health Science Center, Ningbo University, Ningbo, 315211, China., Gao W; College of Information Science and Engineering, Ningbo University, Ningbo, 315211, China. Electronic address: gaowanlei@nbu.edu.cn., Zhang P; Key Laboratory of Photoelectric Materials and Devices of Zhejiang Province, Ningbo University, Ningbo, 315211, China; Engineering Research Center for Advanced Infrared Photoelectric Materials and Devices of Zhejiang Province, Ningbo University, Ningbo, 315211, China. Electronic address: zhangpeiqing@nbu.edu.cn., Zhu Y; Health Science Center, Ningbo University, Ningbo, 315211, China. Electronic address: zhuyabin@nbu.edu.cn.

Publikováno v: Biosensors & bioelectronics [Biosens Bioelectron] 2024 Nov 15; Vol. 264, pp. 116616. Date of Electronic Publication: 2024 Aug 03.

Integrated bulk and single-cell profiling characterize sphingolipid metabolism in pancreatic cancer.

Autor: Zhang B; Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China., Zhang B; Department of Visceral, Vascular and Endocrine Surgery, Martin-Luther-University Halle- Wittenberg, University Medical Center Halle, Halle, Germany., Wang T; Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.; Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, Liaoning, China., Huang B; Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.; Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, Liaoning, China., Cen L; Department of Transfusion Medicine, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, China. 810509659@qq.com.; Key Laboratory of Molecular Pathology in Tumors of Guangxi, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, China. 810509659@qq.com., Wang Z; Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China. wangzhizhou@dmu.edu.cn.

Publikováno v: BMC cancer [BMC Cancer] 2024 Nov 01; Vol. 24 (1), pp. 1347. Date of Electronic Publication: 2024 Nov 01.

Single-cell transcriptomic analysis reveals that the APP-CD74 axis promotes immunosuppression and progression of testicular tumors.

Autor: Chen G; Department of Urology/Pelvic Floor and Andrology, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, PR China., Wang W; Laboratory of Reconstructive Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, PR China., Wei X; Laboratory of Reconstructive Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, PR China., Chen Y; Laboratory of Stem Cell Biology, West China Hospital, West China School of Medicine, Sichuan University, Chengdu, PR China., Peng L; Laboratory of Reconstructive Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, PR China., Qu R; Department of Urology/Pelvic Floor and Andrology, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, PR China., Luo Y; Laboratory of Reconstructive Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, PR China., He S; Department of Urology/Pelvic Floor and Andrology, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, PR China., Liu Y; Department of Urology/Pelvic Floor and Andrology, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, PR China., Du J; Department of Urology/Pelvic Floor and Andrology, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, PR China., Lu R; Laboratory of Stem Cell Biology, West China Hospital, West China School of Medicine, Sichuan University, Chengdu, PR China., Li S; Laboratory of Stem Cell Biology, West China Hospital, West China School of Medicine, Sichuan University, Chengdu, PR China., Fan C; Laboratory of Stem Cell Biology, West China Hospital, West China School of Medicine, Sichuan University, Chengdu, PR China.; Department of Gastrointestinal, Bariatric and Metabolic Surgery, Research Center for Nutrition, Metabolism & Food Safety, West China-PUMC C.C. Chen Institute of Health, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, PR China.; Department of Oncology and Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden., Chen S; Department of Urology/Pelvic Floor and Andrology, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, PR China., Dai Y; Department of Urology/Pelvic Floor and Andrology, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, PR China., Yang L; Department of Urology/Pelvic Floor and Andrology, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, PR China.

Publikováno v: The Journal of pathology [J Pathol] 2024 Nov; Vol. 264 (3), pp. 250-269. Date of Electronic Publication: 2024 Aug 19.

A cost-effective protocol for single-cell RNA sequencing of human skin.

Autor: Khoshbakht S; Graduate School of Health Sciences, Koç University, Istanbul, Türkiye., Albayrak Ö; Koç University Research Center for Translational Medicine, Koç University, Istanbul, Türkiye., Tiryaki E; Graduate School of Health Sciences, Koç University, Istanbul, Türkiye., Ağcaoğlu O; Department of Surgery, Koç University School of Medicine, Istanbul, Türkiye., Öktem A; Department of Dermatology, Ankara University Faculty of Medicine, Ankara, Türkiye., Pınar Sun G; Department of Dermatology, Başakşehir Çam ve Sakura Şehir Hastanesi, Istanbul, Türkiye., Er Gülbezer E; Department of Rheumatology, Koç University School of Medicine, Istanbul, Türkiye., Seda Ertekin S; Department of Dermatology, Koç University School of Medicine, Istanbul, Türkiye., Boyvat A; Department of Dermatology, Ankara University Faculty of Medicine, Ankara, Türkiye., Vural A; Koç University Research Center for Translational Medicine, Koç University, Istanbul, Türkiye.; Department of Neurology, Koç University School of Medicine, Istanbul, Türkiye., Vural S; Koç University Research Center for Translational Medicine, Koç University, Istanbul, Türkiye.; Department of Dermatology, Koç University School of Medicine, Istanbul, Türkiye.

Publikováno v: Frontiers in immunology [Front Immunol] 2024 Oct 30; Vol. 15, pp. 1393017. Date of Electronic Publication: 2024 Oct 30 (Print Publication: 2024).