Zobrazeno 1 - 10
of 770
pro vyhledávání: '"cell‐based therapies"'
Publikováno v:
Journal of Rare Diseases, Vol 3, Iss 1, Pp 1-12 (2024)
Abstract Background Cystic fibrosis (CF) is a fatal genetic disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, disrupting ion transport. This results in organ damage and reduced life expectancy. Main
Externí odkaz:
https://doaj.org/article/cc996d71d27642d39fded2328e3086c3
Autor:
Linfeng Wang, Changbiao Guan, Tao Zhang, Yongchun Zhou, Yuqian Liu, Jianzhong Hu, Daqi Xu, Hongbin Lu
Publikováno v:
Journal of Orthopaedic Translation, Vol 47, Iss , Pp 87-96 (2024)
Background: Bone marrow mesenchymal stem cells (BMSCs) have immense potential in applications for the enhancement of tendon-bone (T-B) healing. Recently, it has been well-reported that skeletal stem cells (SSCs) could induce bone and cartilage regene
Externí odkaz:
https://doaj.org/article/3c99069b9e644d0a84e82cc883d49fbd
Publikováno v:
The Egyptian Journal of Internal Medicine, Vol 36, Iss 1, Pp 1-12 (2024)
Abstract Background Liver fibrosis results from chronic liver injury and is characterized by excessive deposition of extracellular matrix proteins including collagen. It can progress to cirrhosis and liver failure. Main body of the abstract Multiple
Externí odkaz:
https://doaj.org/article/1123886915d142c59b7ba0717849e41b
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Osteosarcoma, a malignant bone tumor predominantly affecting children and adolescents, presents significant therapeutic challenges, particularly in metastatic or recurrent cases. Conventional surgical and chemotherapeutic approaches have achieved par
Externí odkaz:
https://doaj.org/article/3b56ee6259d84fd08c7115db699649ce
Autor:
Gregor Fischer, Linda Bättig, Martin N. Stienen, Armin Curt, Michael G. Fehlings, Nader Hejrati
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Traumatic spinal cord injuries (SCIs) continue to be a major healthcare concern, with a rising prevalence worldwide. In response to this growing medical challenge, considerable scientific attention has been devoted to developing neuroprotective and n
Externí odkaz:
https://doaj.org/article/414b2631783f4b6ab2e4dfb47da930ae
Publikováno v:
European Cells & Materials, Vol 46, Pp 171-194 (2023)
Adipose tissue is an active endocrine organ that can signal bidirectionally to many tissues and organ systems in the body. With obesity, adipose tissue can serve as a source of low-level inflammation that contributes to various co-morbidities and dam
Externí odkaz:
https://doaj.org/article/4e8da21eb95e489ea0b193004a8fb5eb
Autor:
Ana P. Teixeira, Martin Fussenegger
Publikováno v:
Advanced Science, Vol 11, Iss 8, Pp n/a-n/a (2024)
Abstract Arming human cells with synthetic gene circuits enables to expand their capacity to execute superior sensing and response actions, offering tremendous potential for innovative cellular therapeutics. This can be achieved by assembling compone
Externí odkaz:
https://doaj.org/article/d926896b5279433f8cfd78fb9a93938d
Autor:
Bahareh Sadri, Massoud Vosough
Publikováno v:
Cell Journal, Vol 26, Iss 3, Pp 210-211 (2024)
The rapid development of knowledge on healthy nutrition, and hygiene practices, as well as the advent of antibioticsand vaccines, has led to increased life expectancy in the recent century. The extended lifespan has brought newchallenges for healthca
Externí odkaz:
https://doaj.org/article/96271c2808eb482c97bfa66024d9fb57
Autor:
Cláudia S. Oliveira, Freni K. Tavaria
Publikováno v:
Exploration of Immunology, Vol 3, Iss 3, Pp 233-254 (2023)
Besides trauma, several pathological conditions which directly affect the normal functioning of organs, require new therapeutic strategies to repair damaged or diseased tissues. Tissue regeneration is a complex and spatiotemporal process involving a
Externí odkaz:
https://doaj.org/article/90ee1dd7494b4e6eb020781f13a85a7c
Autor:
Rebeca Kennedy-Batalla, Daniel Acevedo, Yiyi Luo, Ana Esteve-Solé, Alexandru Vlagea, Rafael Correa-Rocha, Ma Elena Seoane-Reula, Laia Alsina
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Regulatory T cells (Treg) are essential for immune balance, preventing overreactive responses and autoimmunity. Although traditionally characterized as CD4+CD25+CD127lowFoxP3hi, recent research has revealed diverse Treg subsets such as Tr1, Tr1-like,
Externí odkaz:
https://doaj.org/article/079e20a6751d489581f5e2b0aa1c5aed