Zobrazeno 1 - 10
of 2 198
pro vyhledávání: '"cell‐based assay"'
Autor:
N. K. Ossina, L. T. Volova, P. A. Lebedev, I. A. Shafieva, E. I. Pugachev, S. A. Goncharenko, S. I. Kuznetsov, O. A. Gusyakova, G. N. Svetlova
Publikováno v:
Медицинская иммунология, Vol 26, Iss 5, Pp 897-904 (2024)
Currently, gouty arthritis is considered as a polygenic multifactorial autoinflammatory disease caused by activation of the NOD (nucleotide-binding domain) -like protein receptor 3 inflammasome NLRP3. The two cytokines IL-1β and IL-18 are considered
Externí odkaz:
https://doaj.org/article/3b0c34c471cf4bb68546721cdedfce49
Autor:
Blaž Andlovic, Alexander Wolf, Malgorzata Hiltmann, Bert M. Klebl, Jan Eickhoff, Christian Ottmann
Publikováno v:
SLAS Discovery, Vol 29, Iss 8, Pp 100191- (2024)
The Hippo pathway plays an important role in organ size control and tissue homeostasis. Dysregulation is involved in many pathologies, including cancer, which has attracted interest in targeting the Hippo pathway. Since the upstream components are bo
Externí odkaz:
https://doaj.org/article/25b43e58e9044192aebb9c5e2cea5ea3
Autor:
John R White, Sammina Ahmed, Jan Amstrup, Petra Bennington, Zhijie Jey Cheng, Peter Day, Keneshia K Haenssen, Adi Kozminsky-Atias, Eva Martinez, Esther HQ Ong, Isam Qahwash, Elaine SE Stokes, Jenny Wang
Publikováno v:
BioTechniques, Vol 76, Iss 4, Pp 135-144 (2024)
The BioPhorum Development Group is an industry collaboration enabling the sharing of common practices for the development of biopharmaceuticals. Bioassays are an important part of an analytical control system. Utilization of ready-to-use cells can in
Externí odkaz:
https://doaj.org/article/906e6b3860584bce95f046732311ad20
Autor:
Paulina Duhita Anindita, Yuka Otsuka, Simon Lattmann, Khac Huy Ngo, Chong Wai Liew, CongBao Kang, Reuben S. Harris, Louis Scampavia, Timothy P. Spicer, Dahai Luo
Publikováno v:
SLAS Discovery, Vol 29, Iss 5, Pp 100164- (2024)
Zika virus (ZIKV) continues to pose a significant global public health threat, with recurring regional outbreaks and potential for pandemic spread. Despite often being asymptomatic, ZIKV infections can have severe consequences, including neurological
Externí odkaz:
https://doaj.org/article/08f9bcf98354450598cb5479a707e904
Autor:
Nikola Panic, Marco Marino, Goran Hauser, Silvia Jacobsen, Francesco Curcio, Francesco Meroi, Adriana Cifù, Eleonora Castagnaviz, Cinzia Pistis, Giovanni Terrosu, Milutin Bulajic, Salvatore Francesco Vadalà di Prampero, Dino Tarabar, Irena Krznaric-Zrnic, Gordana Kovacevic, Ivan Ranković, Martina Fabris
Publikováno v:
Gastrointestinal Disorders, Vol 6, Iss 1, Pp 152-163 (2024)
The serological support for early diagnosis and differential diagnosis of inflammatory bowel diseases (IBDs) is actually very limited. In this study, we evaluated the performance of a promising multiparametric method including either well-established
Externí odkaz:
https://doaj.org/article/e5a3273392a845e38f03cebc8ac31cdb
Autor:
Shan He, Jia He, Siying Ma, Kunyu Wei, Fengchang Wu, Jian Xu, Xiaowei Jin, Yuanhui Zhao, Christopher J. Martyniuk
Publikováno v:
Environment International, Vol 188, Iss , Pp 108747- (2024)
Liquid crystal monomers (LCMs) are the raw material for liquid crystal displays, and their use is steadily increasing in electronic products. Recently, LCMs have been reported to be novel endocrine disrupting chemicals, however, the mechanisms underl
Externí odkaz:
https://doaj.org/article/e14212b7aa694f99a0bce605f93458fb
Autor:
Masaki Iizuka, Naomi Nagata, Naomi Kanazawa, Tomomi Iwami, Makoto Nagashima, Masaaki Nakamura, Juntaro Kaneko, Eiji Kitamura, Kazutoshi Nishiyama, Noritaka Mamorita, Takahiro Iizuka
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAnti-NMDA receptor encephalitis is an autoimmune disorder caused by autoantibodies (abs) against the conformational epitope on GluN1 subunits. GluN1-abs have been determined with cell-based assay (CBA) co-expressing GluN1/GluN2 subunits.
Externí odkaz:
https://doaj.org/article/5359f3b475dc46739f635abff26adda4
Autor:
Marieke Hoonakker, Afshin Zariri, Lisette de Brouwer, Dionne David, Anouska Borgman, Arjen Sloots
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionVeterinary vaccines against Clostridium perfringens type C need to be tested for absence of toxicity, as mandated by pharmacopoeias worldwide. This toxicity testing is required at multiple manufacturing steps and relies on outdated mouse
Externí odkaz:
https://doaj.org/article/2eaa5964b3c24348a59f7e8709fb8d23
Autor:
Trivedi, Ritu R. a, Archambault, Angela S. a, Pavlak, Clarice a, Gastaldi, Matteo b, Cantoni, Claudia a, Ghezzi, Laura a, 1, Cross, Anne H. a, Miller, Timothy M. a, Wu, Gregory F. a, c, d, ⁎
Publikováno v:
In Journal of the Neurological Sciences 15 June 2024 461
Publikováno v:
Toxins, Vol 16, Iss 7, p 325 (2024)
Shiga toxin-producing Escherichia coli (STEC) causes a wide spectrum of diseases including hemorrhagic colitis and hemolytic uremic syndrome (HUS). Previously, we developed a rapid, sensitive, and potentially portable assay that identified STEC by de
Externí odkaz:
https://doaj.org/article/9548506e1b9041438cc2c22b5126f9d0