Zobrazeno 1 - 10
of 1 444
pro vyhledávání: '"cd103"'
Autor:
Sayaka Suzuki, Kazuma Komiya, Shogo Tsuda, Miya Yoshino, Tsuneyasu Kaisho, P. Leif Bergsagel, Koji Kawamura, Tetsuya Fukuda, Koji Tokoyoda
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
PurposeType I conventional dendritic cells (cDC1s) play a key role in priming anti-tumor cytotoxic T cells and inducing immune tolerance for self-antigens and tumor antigens. However, it remains unclear whether cDC1 has a protective or pathogenic rol
Externí odkaz:
https://doaj.org/article/cd1dbfd2299c40218accf543c2c70207
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundLeukemia is a prevalent pediatric life-threatening hematologic malignancy with a poor prognosis. Targeting immune checkpoints (ICs) to reverse T cell exhaustion is a potentially effective treatment for leukemia. Tissue resident memory T (TR
Externí odkaz:
https://doaj.org/article/be6fc5d6b8e548439fd93cc285e6e06e
Publikováno v:
Autoimmunity, Vol 57, Iss 1 (2024)
Lupus nephritis (LN) is a highly prevalent complication of systemic lupus erythematosus (SLE). Long non-coding RNAs (lncRNAs) are essential modulators in multiple types of human diseases, including LN. In the current study, we searched on online GEO
Externí odkaz:
https://doaj.org/article/e0a2325bc2f64c16beaf902626ae39e7
Autor:
Guanqun Yang, Siqi Cai, Mengyu Hu, Chaozhuo Li, Liying Yang, Wei Zhang, Jujie Sun, Fenghao Sun, Ligang Xing, Xiaorong Sun
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Tissue-resident memory T (TRM) cells can reside in the tumor microenvironment and are considered the primary response cells to immunotherapy. Heterogeneity in functional status and spatial distribution may contribute to the contro
Externí odkaz:
https://doaj.org/article/650a2c14e9d84836ad6446d0e4a08fa8
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Background Immune checkpoint inhibitors (ICIs) have made significant progress in oncotherapy improving survival of patients. However, the benefits are limited to only a small subgroup of patients who could achieve durable responses. Early pr
Externí odkaz:
https://doaj.org/article/2766395661714f37a72f12e6bba44659
Akademický článek
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Autor:
Xiaoyu Fan, Marta A. Ważyńska, Arjan Kol, Noemi Perujo Holland, Bruna Fernandes, Sander M. J. van Duijnhoven, Annechien Plat, Hans van Eenennaam, Philip H. Elsinga, Hans W. Nijman, Marco de Bruyn
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Background CD103 is an integrin specifically expressed on the surface of cancer-reactive T cells. The number of CD103+ T cells significantly increases during successful immunotherapy and might therefore be an attractive biomarker for noninva
Externí odkaz:
https://doaj.org/article/42504525a87d43f6acda5c05efb66f5a
Autor:
Seiji Natsuki, Hiroaki Tanaka, Masaki Nishiyama, Sota Deguchi, Yuichiro Miki, Mami Yoshii, Tatsuro Tamura, Takahiro Toyokawa, Shigeru Lee, Kiyoshi Maeda
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Immune checkpoint inhibitors (ICIs), including nivolumab, have been approved to treat esophageal cancer. However, these remedies are not fit for all patients with esophageal cancer; therefore, a predictive surrogate marker is need
Externí odkaz:
https://doaj.org/article/027c74f6d3c1470ba9b25ebfa95cf6d5
Autor:
Siqi Ren, Tianjun Lan, Fan Wu, Suling Chen, Xue Jiang, Chuying Huo, Zitian Li, Shule Xie, Donghui Wu, Ruixin Wang, Yanyan Li, Lin Qiu, Guoxin Huang, Shurui Li, Xiaojuan Wang, Meifeng Cen, Tingting Cai, Zhaoyu Lin, Jinsong Li, Bowen Li
Publikováno v:
Cancer Communications, Vol 43, Iss 10, Pp 1143-1163 (2023)
Abstract Background Immune cell heterogenicity is known to determine the therapeutic response to cancer progression. Neoadjuvant chemoimmunotherapy (NACI) has shown clinical benefits in some patients with advanced head and neck squamous cell carcinom
Externí odkaz:
https://doaj.org/article/ebc376bd34f840ac8e1da1d27dc3d371