Zobrazeno 1 - 10
of 193
pro vyhledávání: '"cck1"'
Autor:
Zong Jie Cui, Yuan Li
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 3763, p 3763 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 3763, p 3763 (2020)
In contrast to reversible activation by agonist, cholecystokinin 1 receptor (CCK1R) is permanently activated by singlet oxygen generated in photodynamic action, with sulphonated aluminium phthalocyanine or genetically encoded mini singlet oxygen gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66bffcf7a5cc13f3d09d6930eb94d800
http://europepmc.org/articles/PMC7313028
http://europepmc.org/articles/PMC7313028
Akademický článek
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Publikováno v:
BMC Neuroscience, Vol 13, Iss 1, p 63 (2012)
Abstract Background Cholecystokinin octapeptide (CCK-8), the most potent endogenous anti-opioid peptide, has been shown to regulate the processes of morphine dependence. In our previous study, we found that exogenous CCK-8 attenuated naloxone induced
Externí odkaz:
https://doaj.org/article/0b5daf42742c46c4a26371d0b3812d1b
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
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Autor:
Kyoko Miyasaka, Akihiro Funakoshi, Hiromi Takahashi-Iwanaga, Kohtarou Konno, Toshihiko Iwanaga, Motokazu Uchigashima, Masahiko Watanabe
Publikováno v:
Histochemistry and Cell Biology. 143:301-312
Information concerning the cellular localization of cholecystokinin (CCK)-1 receptors has been discrepant and remained scanty at ultrastructural levels. The present immunohistochemical study at light and electron microscopic levels revealed the disti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eb3d786e6469e31a75852724d501824
https://doi.org/10.1007/s00418-014-1281-3
https://doi.org/10.1007/s00418-014-1281-3
Autor:
H-P Hsu
Publikováno v:
Acta Endocrinologica (Bucharest). 10:373-382
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4671c875aa7243ad02a6777d5e97ace8
https://doi.org/10.4183/aeb.2014.373
https://doi.org/10.4183/aeb.2014.373
Publikováno v:
Journal of Neurogastroenterology and Motility
Background/Aims Prolactin (PRL) is essential for the lactating mammals, while cholecystokinin (CCK) does inhibit gastric emptying (GE). Present study attempted to determine whether both peptides interacted on the male rat GE, particularly the role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5103f3238ddd4e5bc96d20fc14586d27
https://doi.org/10.5056/jnm.2012.18.4.385
https://doi.org/10.5056/jnm.2012.18.4.385
Autor:
Melissa L. Gillaspy, Diane M. Hargrove, Mary E. Lame, Paul Da Silva Jardine, Dennis O. Scott, Catherine E. Trebino, Yingxin Zhang, Kimberly O. Cameron, Richard L. Elliott, Kelly A. Martin, Janice E. Chin, Elena E. Beretta, Swick Andrew Gordon, Jeffrey S. Dubins, Janet A. LaFlamme, Dexue Sun, Tristan S. Maurer, Nancy A. Nardone, Amit S. Kalgutkar, Jeremy A. Bartlett, Robert M. Oliver, Yue Chen
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:6797-6801
We describe the design, synthesis, and structure-activity relationships of triazolobenzodiazepinone CCK1 receptor agonists. Analogs in this series demonstrate potent agonist activity as measured by in vitro and in vivo assays for CCK1 agonism. Our ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeaaaf4e60123f7f9fd8e609d714c16d
https://doi.org/10.1016/j.bmcl.2010.08.115
https://doi.org/10.1016/j.bmcl.2010.08.115
Autor:
Neelakandha S. Mani, Sudip Basu, Josef Moravek, Laurent Gomez, Jiejun Wu, J. Guy Breitenbucher
Publikováno v:
Tetrahedron Letters. 51:1110-1113
Attempts to prepare JNJ 26273364, a highly functionalized pyrazole-based CCK1 receptor antagonist, using a carboxylation reaction led to a series of unexpected results. This work demonstrated the unique reactivity and stability of the highly function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0a1ac034eb0ea43283c05ab6c73b95f
https://doi.org/10.1016/j.tetlet.2009.12.112
https://doi.org/10.1016/j.tetlet.2009.12.112