Zobrazeno 1 - 10
of 37
pro vyhledávání: '"ccRCC, clear cell renal cell carcinoma"'
Autor:
Yihui Yang, Xiangjin Zheng, Sha Li, Jinyi Liu, Wan Li, Jie Yi, Weiqi Fu, Jinhua Wang, Guanhua Du, Liwen Ren
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2783-2797 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Exosomes are cell-derived nanovesicles with diameters from 30 to 150 nm, released upon fusion of multivesicular bodies with the cell surface. They can transport nucleic acids, proteins, and lipids for intercellular communication and activate signalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dfeee0d62636797c4da5264a84ca925
https://doi.org/10.1016/j.apsb.2021.01.001
https://doi.org/10.1016/j.apsb.2021.01.001
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 910-928 (2021)
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 910-928 (2021)
Graphical abstract
Circular RNAs (circRNAs) are a very interesting class of conserved single-stranded RNA molecules derived from exonic or intronic sequences by precursor mRNA back-splicing. Unlike canonical linear RNAs, circRNAs form covalently
Circular RNAs (circRNAs) are a very interesting class of conserved single-stranded RNA molecules derived from exonic or intronic sequences by precursor mRNA back-splicing. Unlike canonical linear RNAs, circRNAs form covalently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08d700dc693b3eae73dc74ae3cdbbdf6
http://europepmc.org/articles/PMC7851342
http://europepmc.org/articles/PMC7851342
Autor:
In Young Park, Cheryl Walker, Michael A. Cianfrocco, Kristen J. Verhey, Sarah Kearns, Frank M. Mason, W. Kimryn Rathmell
Publikováno v:
The Journal of Biological Chemistry
Post-translational modifications to tubulin are important for many microtubule-based functions inside cells. It was recently shown that methylation of tubulin by the histone methyltransferase SETD2 occurs on mitotic spindle microtubules during cell d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b681d14b08f07ae028e8392aaaf0e3
http://europepmc.org/articles/PMC8294582
http://europepmc.org/articles/PMC8294582
Autor:
Adam Pennycuick, Neelam Kumar, Xidan Zhang, Mary Falzon, Krishna K. Kolluri, Ersilia Nigro, Yuki Ishii, Doraid Alrifai, Khalid Shah, Elaine Borg, Sam M. Janes
Publikováno v:
The Journal of Biological Chemistry
Malignant pleural mesothelioma (MPM) is a rare, aggressive, and incurable cancer arising from the mesothelial lining of the pleura, with few available treatment options. We recently reported that loss of function of the nuclear deubiquitinase BRCA1-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b29ae2da35ab58c009cd489419063c2
https://pubmed.ncbi.nlm.nih.gov/34597666
https://pubmed.ncbi.nlm.nih.gov/34597666
Publikováno v:
Translational Oncology
Translational Oncology, Vol 14, Iss 7, Pp 101078-(2021)
Translational Oncology, Vol 14, Iss 7, Pp 101078-(2021)
Highlights • Radiomics profile of clear cell renal cell carcinoma is heterogeneity. • Multi-scale Radiogenomics could link molecular features and images. • Radiomic subtypes could be used for risk stratification.
Background To identify rad
Background To identify rad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a727a4fa3538e24b01ed1c6393ce92c
http://europepmc.org/articles/PMC8065300
http://europepmc.org/articles/PMC8065300
Autor:
Zarema Albakova, Dmitriy Yu. Ryazantsev, Rustam H. Ziganshin, Alexander M. Sapozhnikov, Pradeep Kumar Sacitharan, Mohammad Kawsar Sharif Siam
Publikováno v:
Translational Oncology
Translational Oncology, Vol 14, Iss 2, Pp 100995-(2021)
Translational Oncology, Vol 14, Iss 2, Pp 100995-(2021)
Highlights • High expression of extracellular heat shock proteins (HSPs) indicates highly aggressive tumors. • HSP profiling of extracellular vesicles (EVs) derived from various biological fluids and released by immune cells may open new perspect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d34e1bac419d6e7475ae813521821df
https://pubmed.ncbi.nlm.nih.gov/33338880
https://pubmed.ncbi.nlm.nih.gov/33338880
Autor:
Qiming Zheng, Gonghui Li, Liya Wang, Zeyi Lu, Minxiao Jiang, Danyang Shen, Lifeng Ding, Liqun Xia, Huan Wang, Ruyue Wang
Publikováno v:
Translational Oncology
Translational Oncology, Vol 14, Iss 1, Pp 100974-(2021)
Translational Oncology, Vol 14, Iss 1, Pp 100974-(2021)
Highlights • SncRNAs contribute to the progress of renal cell carcinoma. • SncRNAs are promising biomarkers for diagnosis and prognosis of renal cell carcinoma. • Despite the potential of sncRNA-based cancer therapy, some obstacles remain, incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f5022f3bd3ba544f8e273708c00f90
https://pubmed.ncbi.nlm.nih.gov/33395751
https://pubmed.ncbi.nlm.nih.gov/33395751
Autor:
Geiszler, Daniel J., Kong, Andy T., Avtonomov, Dmitry M., Yu, Fengchao, Leprevost, Felipe V., Nesvizhskii, Alexey I.
Publikováno v:
Molecular & Cellular Proteomics : MCP
Open searching has proven to be an effective strategy for identifying both known and unknown modifications in shotgun proteomics experiments. Rather than being limited to a small set of user-specified modifications, open searches identify peptides wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adaab954dae3eb538974a83cbaf67519
https://pubmed.ncbi.nlm.nih.gov/33568339
https://pubmed.ncbi.nlm.nih.gov/33568339
Autor:
Jee Soo Park, Hyo Jung Lee, Jongchan Kim, Won Sik Ham, Nam Hoon Cho, Won Sik Jang, Ji Eun Heo
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 17, Iss, Pp 371-377 (2019)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Some early-stage clear cell renal cell carcinomas (ccRCCs) of ≤7 cm are associated with a poor clinical outcome. In this study, we investigated molecular biomarkers associated with aggressive clinical T1 stage ccRCCs of ≤7 cm, which were used to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce87778aa5cc8292b92e02d82688531c
https://doi.org/10.1016/j.csbj.2019.03.005
https://doi.org/10.1016/j.csbj.2019.03.005
Autor:
Xiaoxia Liu, Qian Wang, Daici Chen, Yichen Li, Shaoyong Peng, Huaiming Wang, Wanjun Liu, Qianxin Luo, Si Chen
Publikováno v:
Translational Oncology
Translational Oncology, Vol 14, Iss 10, Pp 101171-(2021)
Translational Oncology, Vol 14, Iss 10, Pp 101171-(2021)
Highlights • The association between ORMDL1 expression and clinipathological characteristic in colorectal cancer (CRC) has not been reported before, which is addressed in this study. • Although ORMDL1 is generally upregulated in CRC, high express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05003a7483e84092acde62e356a23bb6
https://doi.org/10.1016/j.tranon.2021.101171
https://doi.org/10.1016/j.tranon.2021.101171