Zobrazeno 1 - 10
of 6 460
pro vyhledávání: '"caveolin-1"'
Autor:
Chika Asai, Naoko Takamura, Tomoya Watanabe, Miho Asami, Noriko Ikeda, Charles F. Reese, Stanley Hoffman, Yukie Yamaguchi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The plasma membrane protein caveolin-1 (CAV-1) regulates signaling by inhibiting a wide range of kinases and other enzymes. Our previous study demonstrated that the downregulation of CAV-1 in psoriatic epidermal cells contributes to inflamma
Externí odkaz:
https://doaj.org/article/50b06ae0e3d641a0b9317dcdb509a433
Publikováno v:
Archives of Medical Science, Vol 20, Iss 3, Pp 887-908 (2024)
Introduction The study was designed to explore how cinobufagin (CB) regulates the development of non-small cell lung cancer (NSCLC) cells through lipid rafts. Material and methods The effects of CB at gradient concentrations (0, 0.5, 1 and 2 µM) on
Externí odkaz:
https://doaj.org/article/2df9d574647646af8ad37b89f852d840
Autor:
Dongsheng Bai, Chen Zhou, Jiaying Du, Jiawei Zhao, Chunyang Gu, YuXiang Wang, Lulu Zhang, Na Lu, Yue Zhao
Publikováno v:
Redox Biology, Vol 75, Iss , Pp 103277- (2024)
Sepsis is a common complication of infections that significantly impacts the survival of critically patients. Currently, effective pharmacological treatment strategies are lacking. Auranofin, known as an inhibitor of Thioredoxin reductase (TrxR), exh
Externí odkaz:
https://doaj.org/article/ffcf4808492c4988af195fd4e3a03c9f
Autor:
Christopher Godina, Mattias Belting, Johan Vallon-Christersson, Karolin Isaksson, Ana Bosch, Helena Jernström
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Combining information from the tumor microenvironment (TME) with PAM50 Risk of Recurrence (ROR) score could improve breast cancer prognostication. Caveolin-1 (CAV1) is a marker of an active TME. CAV1 is a membrane protein involved in cell si
Externí odkaz:
https://doaj.org/article/97f3d582073e472a88a489644135df4a
Publikováno v:
BMC Molecular and Cell Biology, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background Hypertension-induced mechanical stress on vascular smooth muscle cells (VSMCs) is a known risk factor for vascular remodeling, including vascular calcification. Caveolin-1 (Cav-1), an integral structural component of plasma membra
Externí odkaz:
https://doaj.org/article/d3049e26385641fba3a71b51b8fd9349
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 1451-1467 (2024)
Yiyang Li,1,* Jiali Chen,1,* Xingping Quan,1 Ying Chen,2 Yan Han,1 Jinfen Chen,1 Li Yang,1 Youhua Xu,3 Xu Shen,4 Ruibing Wang,1,5 Yonghua Zhao1,5 1Institute of Chinese Medical Sciences, State Key Laboratory of Quality Research in Chinese Medi
Externí odkaz:
https://doaj.org/article/866138c5a6ce4803ba366057f27ce139
Akademický článek
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Autor:
Wuyang Shi, Shibo Sun, Haowen Liu, Yao Meng, Kangshuai Ren, Guoying Wang, Minghui Liu, Jiaqi Wu, Yue Zhang, Huang Huang, Meiyun Shi, Weiping Xu, Qiang Ma, Bingbing Sun, Jianqiang Xu
Publikováno v:
Redox Biology, Vol 70, Iss , Pp 103050- (2024)
Thioredoxin reductase (TXNRD) is a selenoprotein that plays a crucial role in cellular antioxidant defense. Previously, a distinctive guiding bar motif was identified in TXNRD1, which influences the transfer of electrons. In this study, utilizing sin
Externí odkaz:
https://doaj.org/article/a794bd0d20ef4b188abb9772e7ef29ce
Autor:
Pengde Lu, Jinfen Chen, Ying Chen, Xingping Quan, Jiayue Liu, Yan Han, Yiyang Li, Li Yang, Jian‐Bo Wan, Yonghua Zhao
Publikováno v:
Food Frontiers, Vol 4, Iss 4, Pp 2081-2096 (2023)
Abstract Ulcerative colitis (UC) is a digestive disease with a high incidence and is difficult to be cured due to its complex etiology. It has evidenced that intestinal barrier dysfunction plays a predominant role in UC. 20(S)‐protopanaxadiol sapon
Externí odkaz:
https://doaj.org/article/1b8b6d241af54306b270ebe9464dae90
Autor:
Wenxin Tang, Chaoying Yan, Shuxuan He, Mengyu Du, Bo Cheng, Bin Deng, Shan Zhu, Yansong Li, Qiang Wang
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Type 2 diabetes mellitus (T2DM) induced diabetes-associated cognitive dysfunction (DACD) that seriously affects the self-management of T2DM patients, is currently one of the most severe T2DM-associated complications, but the mecha
Externí odkaz:
https://doaj.org/article/d976068debee47cca6ea7eb27f10d8ec